Zobrazeno 1 - 10
of 5 430
pro vyhledávání: '"L-Asparaginase"'
Publikováno v:
Electronic Journal of Biotechnology, Vol 71, Iss , Pp 10-18 (2024)
Background: L-asparaginase (L-ASNase) is an essential enzyme used to treat acute lymphoblastic leukemia (ALL) by depleting L-asparagine, a vital nutrient for leukemia cells. However, its clinical use is challenged by adverse effects linked to its bac
Externí odkaz:
https://doaj.org/article/de710d68f1464e18b936a8f45fe53291
Autor:
Shiyuan Wang, Jun Li, Ying Li, Xiaoming Liu, Lixian Chang, Beibei Zhao, Li Zhang, Yao Zou, Min Ruan, Xiaofan Zhu
Publikováno v:
Global Medical Genetics, Vol 11, Iss 03, Pp 214-219 (2024)
Cerebral venous sinus thrombosis (CVST) and hyperlipidemia are severe complications of L-Asparaginase (L-Asp) during the treatment of B-cell acute lymphoblastic leukemia (B-ALL). Herein, we reported a 9-year-old B-ALL boy who underwent abnormal hyper
Externí odkaz:
https://doaj.org/article/06015c21da73438fb6f8b624df18fedd
Autor:
Jesús Alonso Gándara-Mireles, Ismael Lares-Asseff, Elio Aarón Reyes Espinoza, Verónica Loera Castañeda, Lourdes Patricia Córdova Hurtado, Flor de María Reyes Gutiérrez, Antonio Sandoval-Cabrera, Ignacio Villanueva Fierro, Julio Cesar Grijalva Ávila, Claudia Castro Arreola, Leslie Patrón-Romero, Horacio Almanza Reyes
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionL-Asparaginase (L-Asp) is a key drug in the treatment of acute lymphoblastic leukemia (ALL); however, it is commonly associated with the occurrence of adverse events (AE). Risk factors such as age, sex, nutritional status, and some single
Externí odkaz:
https://doaj.org/article/efdad68448de442eb3d12b3bbfe44f4e
Publikováno v:
AMB Express, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract L-asparaginase is an important therapeutic enzyme that is frequently utilized in the chemotherapy regimens of adults as well as pediatric patients with acute lymphoblastic leukemia. However, a high rate of hypersensitivity with prolonged use
Externí odkaz:
https://doaj.org/article/112bb2c31bf94ef2867170d16072d48c
Autor:
T. T. Valiev, E. V. Kumirova, V. M. Rozinov, T. R. Panferova, I. N. Khvorostov, K. L. Kondratchik, O. Yu. Fuks, P. A. Kerimov, N. V. Matinyan, A. V. Belyaeva, A. M. Efremenkov, A. A. Bystrova, A. P. Kurkin, V. V. Gorev
Publikováno v:
Онкогематология, Vol 19, Iss 2, Pp 141-146 (2024)
L-asparaginase is one of the most effective drugs in pediatric and adult acute lymphoblastic leukemia treatment. But drug side effects are an important problem. pancreatitis and pancreatic necrosis are not common (2–18 %) complication, but high cha
Externí odkaz:
https://doaj.org/article/cfcc39454ebc4d23aac4afd015bc97bd
Autor:
Christina Salvador, Robert Salvador, Gabriele Kropshofer, Bernhard Meister, Marie Rock, Petra Obexer, Benjamin Hetzer, Evelyn Rabensteiner, Roman Crazzolara
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background Thromboembolic complications are well known in the treatment of childhood acute lymphoblastic leukemia. Over the years it has not been possible to reach a consensus on a possible prophylaxis of thromboembolic events during intensi
Externí odkaz:
https://doaj.org/article/97aee1d3077a412ba722b64122000e9e
Autor:
Xenia Vázquez, Pilar Lumbreras-Iglesias, M. Rosario Rodicio, Javier Fernández, Teresa Bernal, Ainhoa Fernández Moreno, Paula López de Ugarriza, Ana Fernández-Verdugo, Abelardo Margolles, Carlos Sabater
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract A dataset comprising metagenomes of outpatients (n = 28) with acute leukemia (AL) and healthy controls (n = 14) was analysed to investigate the associations between gut microbiota composition and metabolic activity and AL. According to the r
Externí odkaz:
https://doaj.org/article/80c568889c834176be8139089e0970d7
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