Dynamic landscape of the intracellular termini of acid-sensing ion channel 1a

Autor: Megan M Cullinan, Robert C Klipp, Abigail Camenisch, John R Bankston

Publikováno v: eLife, Vol 12 (2023)

Acid-sensing ion channels (ASICs) are trimeric proton-gated sodium channels. Recent work has shown that these channels play a role in necroptosis following prolonged acidic exposure like occurs in stroke. The C-terminus of ASIC1a is thought to mediat

Externí odkaz: https://doaj.org/article/217688c146a2459fb987c3950f921eef

Dynamic landscape of the intracellular termini of acid-sensing ion channel 1a.

Autor: Cullinan MM; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Klipp RC; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Camenisch A; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Bankston JR; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 19. Date of Electronic Publication: 2023 Sep 19.