Zobrazeno 1 - 10
of 279
pro vyhledávání: '"L de Leij"'
Publikováno v:
Clinical and Developmental Immunology, Vol 6, Iss 3-4, Pp 261-271 (1998)
Externí odkaz:
https://doaj.org/article/186980cafed946858215ceaa2e1d5f8f
Publikováno v:
Molecular Genetics and Metabolism. 92:299-307
Pompe disease is a rare autosomal recessive lysosomal storage disease caused by deficiency of acid-alpha-glucosidase (GAA). This deficiency results in glycogen accumulation in the lysosomes, leading to lysosomal swelling, cellular damage and organ dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8526158955a1278fe3f9f7efd7128165
https://doi.org/10.1016/j.ymgme.2007.07.009
https://doi.org/10.1016/j.ymgme.2007.07.009
Publikováno v:
Antiviral Research, 69(2), 124-127. ELSEVIER SCIENCE BV
The human cytomegalovirus has found smart ways to exploit the chemokine network in order to subvert immune attack. Chemokines trigger the arrest and firm adhesion of inflammatory cells to the vascular wall. Scavenging of chemokines by viral decoy rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc38fef9354ea19861f1480cd55dd6b
https://doi.org/10.1016/j.antiviral.2005.11.003
https://doi.org/10.1016/j.antiviral.2005.11.003
Autor:
M.A. de Jong, J van Zanten, L. de Leij, Geke A. P. Hospers, Nanno Mulder, A. Setroikromo, M. Elias
Publikováno v:
Journal of clinical apheresis, 20(4), 197-207. Wiley
Dendritic cells (DC) used for clinical trials should be processed oil a large scale conforming to current good manufacturing practice (cGM P) guidelines. The aim of this study was to develop a protocol for clinical grade generation of immature DC in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318000be37e6c1f5c2f5d96311f7ac9f
https://research.rug.nl/en/publications/5af97536-ab89-43bd-b61a-d0efdd788dbb
https://research.rug.nl/en/publications/5af97536-ab89-43bd-b61a-d0efdd788dbb
Publikováno v:
Cell and Tissue Research, 317(3), 289-298. SPRINGER
Extracellular nucleotides have been identified as important signaling molecules. These nucleotides act on the P2 family of receptors that respond by either forming an ion-channel or by activation of a signal transduction cascade, both of which enable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec8f3d3958eb7a0e46e0d9eb2e773a5
https://doi.org/10.1007/s00441-004-0939-x
https://doi.org/10.1007/s00441-004-0939-x
Autor:
René A. Tio, P.B. van Wachem, Josee A. Plantinga, M.J.A. van Luyn, X. J. Gallego y van Seijen, L. de Leij, M.J.L DeJongste
Publikováno v:
Biomaterials. 23:4793-4801
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac tissue engineering by use of a temporary bioscaffold and cardiomyocytes may help to find answers for future treatments in heart failure. For that purp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7398c507a96ab1a5a25e3657d1fe09fa
https://doi.org/10.1016/s0142-9612(02)00230-2
https://doi.org/10.1016/s0142-9612(02)00230-2
Autor:
BJ Kroesen, A Calogero, Alja J Stel, Sebo Withoff, L. de Leij, L Delahaye, M N A Bijman, M. W. A. de Jonge
Publikováno v:
British Jounal of Cancer, 84(8), 1115-1121. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
This paper describes a bi-specific antibody, which was called BIS20x3. It retargets CD3ɛ-positive cells (T-cells) to CD20-positive cells and was obtained by hybrid–hybridoma fusion. BIS20x3 could be isolated readily from quadroma culture supernata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbea5ef34b48cbfb02c5bd970c49fad
https://research.rug.nl/en/publications/ca0c84a5-7299-4b3f-b792-792e491242ad
https://research.rug.nl/en/publications/ca0c84a5-7299-4b3f-b792-792e491242ad
Autor:
P.B. van Wachem, I. M. S. L. Khouw, Josee A. Plantinga, M.J.A. van Luyn, L. de Leij, Bart L. Haagmans
Publikováno v:
Journal of Biomedical Materials Research. 50:259-266
This study was performed to gain more insight into the role of interferon-gamma (IFN-gamma), a potent macrophage activator, in the foreign-body reaction to hexamethylenediisocyanate-crosslinked dermal sheep collagen (HDSC). Because the results of ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e1ec274272afcf8a3a14daea00346c1
https://doi.org/10.1002/(sici)1097-4636(200005)50:2<259::aid-jbm21>3.0.co
https://doi.org/10.1002/(sici)1097-4636(200005)50:2<259::aid-jbm21>3.0.co
Publikováno v:
Journal of Biomedical Materials Research, 54(2), 234-240. Wiley
Subcutaneous implantation of biodegradable hexamethylenediisocyanate crosslinked dermal sheep collagen (HDSC) elicited little foreign-body reaction in mice in contrast to rats. If the factor(s) resulting in this minor foreign-body reaction are better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ea04d5867b24acc77bef3426ec34d2
https://doi.org/10.1002/1097-4636(200102)54:2<234::aid-jbm10>3.0.co
https://doi.org/10.1002/1097-4636(200102)54:2<234::aid-jbm10>3.0.co
Publikováno v:
Journal of Biomedical Materials Research. 41:202-210
Biomaterials are increasingly used for clinical applications. However, loss of function may occur owing to tissue reactions, which are mainly caused by a variety of inflammatory reactions. Recently, we demonstrated that macrophages (MO) and T cells p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a28882e220415325f72a009b6a4528
https://doi.org/10.1002/(sici)1097-4636(199808)41:2<202::aid-jbm4>3.0.co
https://doi.org/10.1002/(sici)1097-4636(199808)41:2<202::aid-jbm4>3.0.co