Zobrazeno 1 - 10
of 23
pro vyhledávání: '"L Y Sakai"'
Autor:
Takako Sasaki, Satoshi Amano, Kuniko Kadoya, K. Matsuzaki, Norio Kumagai, Günter Kostka, Rupert Timpl, Toshio Nishiyama, L. Y. Sakai
Publikováno v:
British Journal of Dermatology. 153:607-612
Summary Background Fibulin-5 was recently found as a secreted extracellular matrix protein that functions as a scaffold for elastic fibres. However, the distribution of fibulin-5 in human skin and its changes during the ageing process are not known.
Publikováno v:
Cornea. 17:309-314
Purpose To characterize the expression of fibrillins, microfibril components, in human corneas with pseudophakic/aphakic (PBK/ABK) bullous keratopathy. Methods Normal and PBK/ABK corneas were stained by immunofluorescence for fibrillin-1 and -2. The
Publikováno v:
Nature. 352:334-337
FIBRILLIN is a large (relative molecular mass 350,000) glyco-protein which can be isolated from fibroblast cell cultures and is a component of the microfibrils that are ubiquitous in the connective tissue space1. The microfibrils of the suspensory li
Publikováno v:
Journal of musculoskeletalneuronal interactions. 6(4)
Autor:
K, Kadoya, T, Sasaki, G, Kostka, R, Timpl, K, Matsuzaki, N, Kumagai, L Y, Sakai, T, Nishiyama, S, Amano
Publikováno v:
The British journal of dermatology. 153(3)
Fibulin-5 was recently found as a secreted extracellular matrix protein that functions as a scaffold for elastic fibres. However, the distribution of fibulin-5 in human skin and its changes during the ageing process are not known.To explore the invol
Publikováno v:
The Journal of biological chemistry. 275(16)
Most extracellular proteins consist of various modules with distinct functions. Mutations in one common type, the calcium-binding epidermal growth factor-like module (cbEGF), can lead to a variety of genetic disorders. Here, we describe as a model sy
Publikováno v:
The Journal of biological chemistry. 275(3)
Fibrillins are the major constituents of extracellular microfibrils. How fibrillin molecules assemble into microfibrils is not known. Sequential extractions and pulse-chase labeling of organ cultures of embryonic chick aortae revealed rapid formation
Publikováno v:
Cornea. 17(3)
To characterize the expression of fibrillins, microfibril components, in human corneas with pseudophakic/aphakic (PBK/ABK) bullous keratopathy.Normal and PBK/ABK corneas were stained by immunofluorescence for fibrillin-1 and -2. The expression of fib
Publikováno v:
Investigative ophthalmologyvisual science. 38(5)
To localize the distribution of fibrillin-containing microfibrils in normal human anterior segment tissues and to characterize the role of fibrillin in the pathogenesis of pseudoexfoliation syndrome.Anterior segment tissues were obtained from 10 eyes
Publikováno v:
Ciba Foundation symposium. 192
Fibrillin is a very large molecule whose primary structure is now known from the cloning and sequencing of 10 kb of cDNA. Immunohistochemical results suggest that one of the functions of fibrillin molecules is to contribute to the structure of the mi