Zobrazeno 1 - 10 of 24 pro vyhledávání: '"L W Klassen"'
2
The chemistry and biological effects of malondialdehyde-acetaldehyde adducts
Autor: G M, Thiele, S, Worrall, D J, Tuma, L W, Klassen, T A, Wyatt, N, Nagata
Publikováno v: Alcoholism, clinical and experimental research. 25(5 Suppl)
This article represents the proceedings of a workshop at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Geoffrey M. Thiele and Simon Worrall. The presentations were (1) The chemistry of malondialdehyde-acetaldehyde (MAA) adducts, by Dean
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fff28719265eabb1e2cd8cc7f3ff9f7d
https://pubmed.ncbi.nlm.nih.gov/11391074
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3
Treatment of early seropositive rheumatoid arthritis with minocycline: four-year followup of a double-blind, placebo-controlled trial
Autor: J R, O'Dell, G, Paulsen, C E, Haire, K, Blakely, W, Palmer, S, Wees, P J, Eckhoff, L W, Klassen, M, Churchill, D, Doud, A, Weaver, G F, Moore
Publikováno v: Arthritis and rheumatism. 42(8)
Rheumatoid arthritis (RA) causes substantial morbidity and mortality, and current treatments are suboptimal. Recent studies have demonstrated the short-term efficacy of minocycline in the treatment of patients with early RA. This study was undertaken
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dcc2b495af0ba75c0161f40edd3282b8
https://pubmed.ncbi.nlm.nih.gov/10446869
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4
Conversion of acetaldehyde-protein adduct epitopes from a nonreduced to a reduced phenotype by antigen processing cells
Autor: L W, Klassen, B L, Jones, M F, Sorrell, D J, Tuma, G M, Thiele
Publikováno v: Alcoholism, clinical and experimental research. 23(4)
Many investigators have suggested that an immune reaction to acetaldehyde-protein adducts may be involved in the development and/or progression of alcohol liver disease. The most often reported acetaldehyde adduct is the reduced adduct prepared in vi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3fa4cc84b90daf03c77cc7992c9c343f
https://pubmed.ncbi.nlm.nih.gov/10235301
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5
Soluble proteins modified with acetaldehyde and malondialdehyde are immunogenic in the absence of adjuvant
Autor: G M, Thiele, D J, Tuma, M S, Willis, J A, Miller, T L, McDonald, M F, Sorrell, L W, Klassen
Publikováno v: Alcoholism, clinical and experimental research. 22(8)
Recent studies have shown that the alcohol metabolites malondialdehyde and acetaldehyde can combine to form a stable adduct (MAA) on proteins. This adduct has been detected in the livers of rats chronically consuming ethanol, and serum antibodies to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::324f945af150c695509f86538889d862
https://pubmed.ncbi.nlm.nih.gov/9835288
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6
The use of outcome measures to evaluate clinical rheumatology curriculum changes
Autor: J R, O'Dell, L W, Klassen, G F, Moore
Publikováno v: The Journal of rheumatology. 20(6)
Five years ago we sought to change the comprehensive educational program of our rheumatology clinical training period for internal medicine residents and develop a model to measure the outcome of the curriculum change.During the month-long clinical t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af26b0694de6faa695dc39d9937c386d
https://pubmed.ncbi.nlm.nih.gov/8350310
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8
Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes
Autor: H T Petrie, L W Klassen, H D Kay
Publikováno v: The Journal of Immunology. 134:230-234
Peripheral blood granulocytes from normal healthy donors were found to reproducibly inhibit the cytolytic effector function of specifically sensitized cytotoxic T lymphocytes in vitro when co-incubated with these effector cells and target cells in 8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ba9066be590cb59527294dd6b7e9b5e
https://doi.org/10.4049/jimmunol.134.1.230
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9
Inhibition of human cytotoxic T lymphocyte activity in vitro by autologous peripheral blood granulocytes
Autor: H T, Petrie, L W, Klassen, H D, Kay
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 134(1)
Peripheral blood granulocytes from normal healthy donors were found to reproducibly inhibit the cytolytic effector function of specifically sensitized cytotoxic T lymphocytes in vitro when co-incubated with these effector cells and target cells in 8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::419f25adf27818add7ff82840c8947c4
https://pubmed.ncbi.nlm.nih.gov/3871101
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10
Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants
Autor: J W, Kugler, J O, Armitage, C M, Helms, L W, Klassen, N E, Goeken, G B, Ahmann, R D, Gingrich, W, Johnson, M J, Gilchrist
Publikováno v: The American journal of medicine. 74(2)
Nosocomial pneumonia caused by Legionella pneumophila serogroup 1 occurred in five patients after bone marrow transplantation for hematologic malignancies. Two patients died as a result of the infection despite treatment with erythromycin. Serologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87ca430e6c87e297483c91cf6f3fe5c6
https://pubmed.ncbi.nlm.nih.gov/6337488
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