Zobrazeno 1 - 10 of 25 pro vyhledávání: '"L W Kanja"'
1
Prediction of dose-dependent in vivo acetylcholinesterase inhibition by profenofos in rats and humans using physiologically based kinetic (PBK) modeling-facilitated reverse dosimetry
Autor: Isaac Omwenga, Hans G.J. Mol, Jochem Louisse, L W Kanja, Ivonne M.C.M. Rietjens, Shensheng Zhao
Publikováno v: Archives of Toxicology
Archives of Toxicology, 95(4), 1287-1301
Archives of Toxicology 95 (2021) 4
Organophosphate pesticides (OPs) are known to inhibit acetylcholine esterase (AChE), a critical effect used to establish health-based guidance values. This study developed a combined in vitro–in silico approach to predict AChE inhibition by the OP
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af41e6157aa8ed605593b2ae183a530e
https://doi.org/10.1007/s00204-021-03004-4
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2
Acute Toxicity, Phytochemical Screening, Analgesic, and Anti-Inflammatory Activities of Aqueous and Methanol Root Extracts of Maerua triphylla A. Rich. (Capparaceae)
Autor: Brian Muyukani Wangusi, Jared Misonge Onyancha, L W Kanja, Isaac Mpapuluu Ole-Mapenay
Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)
Maerua triphylla root extracts are used by Maasai and Kikuyu communities in Kenya to manage headaches, stomachaches, migraines, and rheumatism. However, scientific data on their safety and efficacy are limited. The current study aims to investigate t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0504a66bbc04208a125726c2c88aaf
https://doaj.org/article/37f7921ef1264818bf40cd7526d577fe
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3
Organophosphate and carbamate pesticide residues and accompanying risks in commonly consumed vegetables in Kenya
Autor: L W Kanja, Hans G.J. Mol, Paul Zomer, Ivonne M.C.M. Rietjens, Isaac Omwenga, Jochem Louisse
Publikováno v: Food Additives and Contaminants: Part B Surveillance 14 (2021) 1
Food Additives and Contaminants: Part B Surveillance, 14(1), 48-58
The current study was conducted to assess the levels of organophosphates and carbamates in vegetables in Kenya and to examine potential consumer health risks. A total of 90 samples were analysed by liquid chromatography/high-resolution tandem mass sp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95f2d0c8fb088862c3cb667ad2d42b
https://research.wur.nl/en/publications/organophosphate-and-carbamate-pesticide-residues-and-accompanying
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4
Effects of the Use of Good Agricultural Practices on Aflatoxin Levels in Maize Grown in Nandi County, Kenya
Autor: James M. Mbaria, L W Kanja, Penina Afwande Ateku, Vesa Joutsjoki, Grace Nkirote Marete, Mitchel Otieno Okumu, Hannu Korhonen
Publikováno v: Sci, Vol 2, Iss 85, p 85 (2020)
Sci
Volume 1
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Volume 2
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Aflatoxin contaminated maize is of public health concern in Kenya. Training farmers on good agricultural practice (GAP) has been touted as a mitigative measure. Little is known of the effect of such training on aflatoxin levels in maize grown in Keny
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c14887542ac77486e7bca3ff9dbb06c
https://www.mdpi.com/2413-4155/2/4/85
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5
Mitigative effects of Moringa oleifera against liver injury induced by artesunate-amodiaquine antimalarial combination in wistar rats
Autor: Daniel Waweru Gakuya, James M. Mbaria, Francis Okumu Ochola, Alice Wairimu Kinyua, P.O. Okumu, L W Kanja, Mitchel Otieno Okumu, Stephen G. Kiama
Publikováno v: Clinical Phytoscience, Vol 3, Iss 1, Pp 1-8 (2017)
Background Artesunate-amodiaquine (AS-AQ) is an antimalarial drug. It is associated with improved cure rates, accelerated response to therapy and delayed development of resistance. However, liver damage, neurotoxicity and agranulocytosis have been re
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65cfdfd9290293bcb1a45280bf082e
http://link.springer.com/article/10.1186/s40816-017-0052-9
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6
Acute toxicity of the aqueous-methanolic Moringa oleifera (Lam) leaf extract on female Wistar albino rats
Autor: P.O. Okumu, L W Kanja, Mitchel Otieno Okumu, Stephen G. Kiama, James M. Mbaria, Francis Okumu Ochola, Daniel Waweru Gakuya
Publikováno v: International Journal of Basic and Clinical Pharmacology. :1856-1861
Background: Herbal preparations are widely assumed to be safe on oral administration and therefore the documentation of the toxic potential of some herbal concoctions used as medicine and nutrients is limited. Moringa oleifera ( MO ) is a plant that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b025835b5179895236e7c26644a99a24
https://doi.org/10.18203/2319-2003.ijbcp20163153
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7
The legislative and regulatory framework governing herbal medicine use and practice in Kenya: a review
Autor: James M. Mbaria, Allan Odhiambo Onyango, Daniel Waweru Gakuya, L W Kanja, Mitchel Otieno Okumu, Stephen G. Kiama, Mary Atieno Onyango, Francis Okumu Ochola
Publikováno v: Pan African Medical Journal; Vol 28, No 1 (2017)
The Pan African Medical Journal
Complementary and alternative medicine is an integral component of primary healthcare in Kenya. This is because the infrastructural health setup in the country is inadequate in catering for all the medical needs of the population. This particularly h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076a82991ed16dcd59f09be3dc9fbe10
https://doi.org/10.11604/pamj.2017.28.232.12585
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8
Assessment of lead and cadmium residues in farmed fish in Machakos and Kiambu counties, Kenya
Autor: Joseph Mwanzia Nguta, L W Kanja, James M. Mbaria, Isaac Omwenga, Patrick Irungu
Publikováno v: Toxicological & Environmental Chemistry. 96:58-67
Lead (Pb) and cadmium (Cd) concentrations were determined in muscle, gonad, liver and brain of tilapia fish caught from fish ponds in Machakos and Kiambu counties in Kenya. A total of 217 fish samples were randomly sampled from the two counties. Acid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42b6f647da99b835499c72a7a4add536
https://doi.org/10.1080/02772248.2014.911541
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9
Acute and sub-acute toxicity study of the root extracts of Fagaropsis hildebrandtii in mice and evaluation of their antimicrobial effects
Autor: Nduhiu Gitahi, L W Kanja, Mitchel Otieno Okumu, P.O. Okumu, Beatrice Mwende Muia, James M. Mbaria
Publikováno v: F1000Research. 8:1444
Background: Among the Kamba community of Kenya, roots of Fagaropsis hildebrandtii (FH) are boiled and used in managing cough, fertility problems, and microbial infections. The safety of this plant in oral administration and the validity of the ethnom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce34fae1ecf043e31ab9ec0fa33164f
https://doi.org/10.12688/f1000research.19915.1
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10
EFFICACY OF ANTIMICROBIAL ACTIVITY OF GARLIC EXTRACTS ON BACTERIAL PATHOGENS COMMONLY FOUND TO CONTAMINATE MEAT
Autor: L, Njue, L W, Kanja, J N, Ombui, J G, Nduhiu, D, Obiero
Publikováno v: East African medical journal. 91(12)
Meat is amajor source of food and raw materials for a number of industries, yet a lot of meat is wasted each year due to deterioration as a result of spoilage by microorganisms such as Pseudomonas, Acinetobacter, Moraxella, Bacillus, Campylobacter, E
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::609233beebd8f3cd5ec8b557a3a6b4fc
https://pubmed.ncbi.nlm.nih.gov/26859012
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