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Transmammary delivery of firocoxib to piglets reduces stress and improves average daily gain after castration, tail docking, and teeth clipping1

Autor: Katie E. Kleinhenz, Majid Jaberi-Douraki, Teresa Schieber, L. W. Wulf, Jon Seagen, Pritam K. Sidhu, Vickie L. Cooper, Reza Mazloom, Kelly Lechtenberg, Johann F. Coetzee, Michael D. Kleinhenz

Publikováno v: Journal of Animal Science. 97:2750-2768

Painful processing procedures in piglets such as tail docking, castration, and teeth clipping are an emerging animal welfare concern. We hypothesized that transmammary delivery of a nonsteroidal anti-inflammatory drug, firocoxib, would reduce pain as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b72677516220aceebc1ea1d58fa1cd8
https://doi.org/10.1093/jas/skz143

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Randomized controlled trial comparison of analgesic drugs for control of pain associated with induced lameness in lactating dairy cattle

Autor: Johann F. Coetzee, Jennifer A. Schleining, R. Warner, Patrick J. Gorden, L. W. Wulf, Michael D. Kleinhenz, J.A. Ydstie

Publikováno v: Journal of dairy science. 104(2)

Both the economic loss and welfare implications of lameness affect the dairy industry. Currently no analgesic drugs are approved to alleviate lameness-associated pain in lactating dairy cattle in the United States. In this randomized controlled trial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbb12af51e676eb7924c0c7e1d70a85
https://pubmed.ncbi.nlm.nih.gov/33309349

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Pharmacokinetics and pharmacodynamics after oral administration of tapentadol hydrochloride in dogs

Autor: L. W. Wulf, Jonathan Dyce, Johann F. Coetzee, Phillip Lerche, Turi K. Aarnes, James Howard, Jeffrey Lakritz

Publikováno v: American Journal of Veterinary Research. 79:367-375

OBJECTIVE To evaluate pharmacokinetic and pharmacodynamic characteristics of 3 doses of tapentadol hydrochloride orally administered in dogs. ANIMALS 6 healthy adult mixed-breed dogs. PROCEDURES In a prospective, randomized crossover study, dogs were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d80273d4c7fbfe4e7bcea3e5308cb8
https://doi.org/10.2460/ajvr.79.4.367

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Variation in water disappearance, daily dose, and synovial fluid concentrations of tylvalosin and 3-O-acetyltylosin in commerical pigs during five day water medication with tylvalosin under field conditions

Autor: Phillip C. Gauger, Johann F. Coetzee, C. Wang, Kristin Skoland, Locke A. Karriker, Paisley Canning, Jessica L. Bates, Suzanne M. Rajewski, L. W. Wulf, Alejandro Ramirez

Publikováno v: Journal of Veterinary Pharmacology and Therapeutics. 41:632-636

Tylvalosin (TVN) is a water soluble macrolide used in swine production to treat enteric, respiratory, and arthritic pathogens. There is limited data on its distribution to synovial fluid beyond gavage studies, which do not represent field conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a191798b5af3a3c7c0e0c9257c91a2
https://doi.org/10.1111/jvp.12503

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Pharmacokinetics and tissue concentrations of firocoxib in sows following oral administration

Autor: Yuntao Zhang, Johann F. Coetzee, Michael D. Kleinhenz, Pritam K. Sidhu, L. W. Wulf, Carissa Odland, Todd E. Williams, Alyson H. Fitzgerald

Publikováno v: Journal of veterinary pharmacology and therapeuticsREFERENCES. 43(5)

The objectives of this study were to describe the pharmacokinetics of firocoxib following oral (PO) dosing and intravenous (IV) injection in sows. Seven healthy sows were administered 0.5 mg firocoxib/kg IV. Following a 23-d washout period, sows were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41553e986614d45f84c85a94ff05453
https://pubmed.ncbi.nlm.nih.gov/32266983

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PSI-4 Comparison of analgesics for control of lameness-associated pain in lactating dairy cattle

Autor: Johann F. Coetzee, J.A. Ydstie, Jennifer A. Schleining, L. W. Wulf, Patrick J. Gorden, Rochelle Warner, Michael D. Kleinhenz

Publikováno v: J Anim Sci

Both the economic loss and welfare implications of lameness vastly impact the dairy industry. There is a need for effective modalities of analgesia to minimize welfare concerns regarding lameness associated pain in lactating dairy cattle. To date, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9600f5fcad12669f512f1df841aada3d
https://europepmc.org/articles/PMC6666973/

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Tear Fluid Pharmacokinetics Following Oral Prednisone Administration in Dogs With and Without Conjunctivitis

Autor: Lionel Sebbag, Yuqi Yan, Rachel A. Allbaugh, L. W. Wulf, Joe S. Smith, Jonathan P. Mochel

Publikováno v: Journal of Ocular Pharmacology and Therapeutics

Purpose: To describe the pharmacokinetics (PK) of prednisone and prednisolone in tear fluid of dogs receiving oral prednisone at anti-inflammatory to immunosuppressive doses and to assess the impact of induced conjunctivitis on lacrimal drug levels.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc8ae668b7bba52301eb4bf073d7d0
https://pubmed.ncbi.nlm.nih.gov/31070497

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Impact of carprofen administration on stress and nociception responses of calves to cautery dehorning1

Autor: Johann F. Coetzee, L. Labeur, L. A. Barth, N. K. Van Engen, Ronette Gehring, L. W. Wulf, E. A. Voris, C. Wang, Suzanne T. Millman, Matthew L. Stock, Walter H. Hsu

Publikováno v: Journal of Animal Science. 94:542-555

The objective of this study was to investigate the effects of carprofen administered immediately before cautery dehorning on nociception and stress. Forty Holstein calves aged approximately 6 to 8 wk old were either placebo treated and sham dehorned

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d232b9d027870579976666c81864cee3
https://doi.org/10.2527/jas.2015-9510

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An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows

Autor: Locke A. Karriker, Johann F. Coetzee, Dongping Zeng, Christine Mainquist-Whigham, Zhoumeng Lin, Miao Li, Ronette Gehring, L. W. Wulf, Jim E. Riviere

Publikováno v: Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461. Blackwell Publishing Ltd

Penicillin G is widely used in food-producing animals at extralabel doses and is one of the most frequently identified violative drug residues in animal-derived food products. In this study, the plasma pharmacokinetics and tissue residue depletion of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674b7fd0b330a76e006e65e585f0a74a
https://pubmed.ncbi.nlm.nih.gov/31012501

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Pneumatic dart delivery of tulathromycin in calves results in lower antimicrobial concentrations and increased biomarkers of stress and injection site inflammation compared with subcutaneous injection

Autor: Johann F. Coetzee, Butch KuKanich, Joe S. Smith, Michael D. Kleinhenz, Drew R. Magstadt, L. W. Wulf, Patrick J. Gorden, Nicholas K Van Engen, Vickie L. Cooper, Nathan Rand

Publikováno v: Journal of animal science. 96(8)

Remote drug delivery (RDD) using pneumatic darts has become more prevalent in situations where cattle handling facilities are not available. The objective of this study was to compare the effect of pneumatic dart delivery and subcutaneous injection o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f513cfdc8be14d54425a8e742cf1427
https://pubmed.ncbi.nlm.nih.gov/29873747

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