Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L W, Fornwald"'
Autor:
G, Ramakrishna, A, Bialkowska, C, Perella, L, Birely, L W, Fornwald, B A, Diwan, Y H, Shiao, L M, Anderson
Publikováno v:
Molecular carcinogenesis. 28(3)
Codon 12 mutations are frequent in the Ki-ras oncogene in human lung adenocarcinomas, but the effects of these alterations have not been well characterized in lung epithelial cells. Murine primary lung tumors derived from peripheral epithelial cells
Autor:
P V, Nerurkar, H A, Schut, L M, Anderson, C W, Riggs, L W, Fornwald, C D, Davis, E G, Snyderwine, S S, Thorgeirsson, W W, Weber, J M, Rice, G N, Levy
Publikováno v:
Molecular pharmacology. 49(5)
The potent food mutagen/carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) undergoes metabolic N-hydroxylation by cytochromes P450, including cytochrome P450 1A2, followed by generation of an unstable ester catalyzed by acetyltransferases; promu
Publikováno v:
Cancer research. 55(21)
To investigate the hypothesis that tumor promotion by chlorinated aromatic hydrocarbons involves Ah receptor occupation and subsequent induction of cytochromes P-450 1a-1, effects of Aroclor 1254 or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were exa