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Panic results in unique molecular and network changes in the amygdala that facilitate fear responses
Autor:
A.R. Abreu, Stephanie D. Fitz, Amy D. Dietrich, L. Ver Donck, M Ceusters, Izabela F Caliman, Anantha Shekhar, Philip L. Johnson, Erik T. Dustrude, Jodi L. Lukkes, Andrei I. Molosh, J M Kent, William A. Truitt
Publikováno v:
Molecular psychiatry
Recurrent panic attacks (PAs) are a common feature of panic disorder (PD) and post-traumatic stress disorder (PTSD). Several distinct brain regions are involved in the regulation of panic responses, such as perifornical hypothalamus (PeF), periaquedu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c606ff3fc529b5f8d6e04fbc6dcec
https://pubmed.ncbi.nlm.nih.gov/30108314
https://pubmed.ncbi.nlm.nih.gov/30108314
Autor:
Pieter J. Klein, Athanasios Metaxas, Josée E. Leysen, Roland Willems, B.N.M. van Berckel, V.A. Renjaän, Albert D. Windhorst, Esther J.M. Kooijman, L. Ver Donck
Publikováno v:
Journal of Neuroscience Research. 92:1599-1607
Although both the onset of schizophrenia and human phencyclidine (PCP) abuse typically present within the interval from adolescence to early adulthood, the majority of preclinical research employing the PCP model of schizophrenia has been conducted o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f3eb2d7d171bed84b3aeef8152639f
https://doi.org/10.1002/jnr.23433
https://doi.org/10.1002/jnr.23433
Autor:
J. Van Audekerke, Jelle Veraart, Jan Sijbers, Claire Mackie, Elisabeth Jonckers, Roland Willems, Michele Giugliano, Koen Wuyts, Marleen Verhoye, L. Ver Donck, João Couto, Thomas Steckler, A. Van der Linden, S. Sekar, Stefanie Dedeurwaerdere
Publikováno v:
Psychopharmacology
Psychopharmacology; Vol 227
Psychopharmacology; Vol 227
Background An effective NMDA antagonist imaging modelmay find key utility in advancing schizophrenia drug discoveryresearch. We investigated effects ofsubchronictreatmentwith the NMDA antagonist memantine by usingbehavioural observation and multimoda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf57340ee8849c6a6c06e2e39af20bd
Autor:
Ana María Gómez, Marcel A.G. van der Heyden, Sridharan Rajamani, Peter Oosterhoff, Luiz Belardinelli, Sylvain Richard, Patricia Neco, Nico J. M. Attevelt, Jet D.M. Beekman, L. Ver Donck, Avram Oros, M. Houtman, M A Vos, Gudrun Antoons
Publikováno v:
British Journal of Pharmacology. 161:162-175
BACKGROUND AND PURPOSE The high predisposition to Torsade de Pointes (TdP) in dogs with chronic AV-block (CAVB) is well documented. The anti-arrhythmic efficacy and mode of action of Ca2+ channel antagonists, flunarizine and verapamil against TdP wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d17cdd7d4645908824d8184a4997d3b
https://doi.org/10.1111/j.1476-5381.2010.00883.x
https://doi.org/10.1111/j.1476-5381.2010.00883.x
Autor:
C. Nolten, Wilhelmus Drinkenburg, H. De Bosschere, L. Ver Donck, A. van Hemelrijck, Piet Deprez, Sara Torfs, Laurence Lefère, P. Claes, Romain Lefebvre, G. Van de Walle, Catherine Delesalle
Publikováno v:
Equine Veterinary Journal. 40:326-331
Summary Reasons for performing study: Increased plasma (5-HT) concentrations are reported in horses predisposed to develop laminitis and after i.v. infusion of endotoxins. In the equine jejunum contractile 5-HT1A-like receptors show tachyphylaxia upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40aa7be65c9020a9435ac0e7148b39c4
https://doi.org/10.2746/042516408x293583
https://doi.org/10.2746/042516408x293583
Publikováno v:
British Journal of Pharmacology. 153:1550-1557
Background and purpose: The finding that obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's stimulatory effect on food intake and gastric emptying has been questioned. The effect of obestatin has been mostly investigated in fasted ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f5d7455e9d35c7deb080d6ca56a19af
https://doi.org/10.1038/sj.bjp.0707683
https://doi.org/10.1038/sj.bjp.0707683
Publikováno v:
European Journal of Pharmacology. 568:234-241
Muscarinic agonists are known to enhance small intestinal contractions. A similar effect was also seen in pilot experiments with a nucleoside transport inhibitor. However, there is no information on their effects on the spatial pattern of action pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e431523c019a84f8e83bb5bda4015c01
https://doi.org/10.1016/j.ejphar.2007.03.059
https://doi.org/10.1016/j.ejphar.2007.03.059
Publikováno v:
Neurogastroenterology and Motility. 18:569-577
There is limited data available on the electrical activity of the rectum. An in vivo canine model was developed to record 240 extracellular electrograms simultaneously from the serosal surface of the rectum thereby enabling an off-line reconstruction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed6411f093d77af358063d0970df172
https://doi.org/10.1111/j.1365-2982.2006.00791.x
https://doi.org/10.1111/j.1365-2982.2006.00791.x
Autor:
A, Metaxas, R, Willems, E J M, Kooijman, V A, Renjaän, P J, Klein, A D, Windhorst, L Ver, Donck, J E, Leysen, B N M van, Berckel
Publikováno v:
Journal of neuroscience research. 92(11)
Although both the onset of schizophrenia and human phencyclidine (PCP) abuse typically present within the interval from adolescence to early adulthood, the majority of preclinical research employing the PCP model of schizophrenia has been conducted o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c721a07b75a7e771bc25ed680801c3c
https://pubmed.ncbi.nlm.nih.gov/24953757
https://pubmed.ncbi.nlm.nih.gov/24953757