Zobrazeno 1 - 10
of 75
pro vyhledávání: '"L V Topchieva"'
Publikováno v:
Терапевтический архив, Vol 91, Iss 4, Pp 21-27 (2019)
Aim. A comparative analysis of the complex of clinical and laboratory indicators (including the content of cytokines in blood plasma and the level of expression of TNF and IL6 genes in peripheral leukocytes, as well as the level of biochemical and mo
Externí odkaz:
https://doaj.org/article/63c09ea3fc934c2f8a3f0307d7a9f064
Publikováno v:
Терапевтический архив, Vol 90, Iss 5, Pp 72-75 (2018)
The aim of this research was studying the level of DROSHA and DICER genes expression in peripheral mononuclear blood cells (PBMC) in rheumatoid arthritis (RA) patients under methotrexate therapy. Materials and methods. 82 people (from 45 to 70 years)
Externí odkaz:
https://doaj.org/article/8d07ff1b9eb9427eb86e62e3ef2b3d0e
Publikováno v:
Терапевтический архив, Vol 89, Iss 12, Pp 64-67 (2017)
Aim. To investigate the association of the polymorphic marker -3279 C>A of the FOXP3 gene with the risk of pulmonary sarcoidosis (PS) and to estimate the transcription level of this gene in the carriers of different genotypes of this polymorphic mark
Externí odkaz:
https://doaj.org/article/b12f65581e334ccb8ca3aaab141cdf87
Publikováno v:
Терапевтический архив, Vol 89, Iss 3, Pp 61-64 (2017)
Aim. To analyze an association of TNF –308G>A polymorphism with a risk for pulmonary sarcoidosis (PS) in the Russian population of the Republic of Karelia Subjects and methods. 84 patients with persistent PS and 96 donors without clinical manifesta
Externí odkaz:
https://doaj.org/article/21b9a28d58e244cdb89146aa2ba3e0d1
Publikováno v:
Туберкулез и болезни лёгких, Vol 100, Iss 9, Pp 16-20 (2022)
The objective: to analyze the association of the Asp299Gln (rs 4986790) and Thr399Ile(rs 4986791) polymorphisms of the TLR4 gene with the risk of pulmonary sarcoidosis in the Russian population of the Republic of Karelia.Subjects and Methods. 253 peo
Externí odkaz:
https://doaj.org/article/fee7e12e81ef46ec9f8c0a116edced6a
Publikováno v:
Медицинская иммунология, Vol 24, Iss 4, Pp 849-852 (2022)
Genetic factors play an important role in the development and progression of many disorders including lung sarcoidosis which is a systemic inflammatory granulomatous disease of unknown etiology, characterized by the formation of epithelioid cell gran
Externí odkaz:
https://doaj.org/article/ae6653bb71f145979919c946f6076610
Publikováno v:
Медицинская иммунология, Vol 24, Iss 2, Pp 273-282 (2022)
Impaired balance of T regulatory and T effector lymphocytes has recently been considered as an important pathogenetic link in arterial hypertension (AH). There are, however, contradictory literature data about contents of these cells in the patients
Externí odkaz:
https://doaj.org/article/a4afa794f400419a82d40e8aa819f73c
Publikováno v:
Медицинская иммунология, Vol 23, Iss 1, Pp 7-16 (2021)
Sarcoidosis is a systemic inflammatory disease of unknown etiology, characterized by the formation of epithelioid cell granulomas, multisystem lesions with a certain frequency of involvement of various organs, mainly the lungs (up to 90% of cases). O
Externí odkaz:
https://doaj.org/article/d304e54c0aa94b6fb8b386fe60e8a4e2
Publikováno v:
Научно-практическая ревматология, Vol 58, Iss 3, Pp 281-285 (2020)
Objective: to analyze the association of the polymorphic marker rs4537545 (C>T) in the IL6R gene with the development of rheumatoid arthritis (RA) in the population of the Republic of Karelia. Subjects and methods. The investigation included 190 samp
Externí odkaz:
https://doaj.org/article/1a99d673bea74347aab3da443f000dff
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 24, Iss 1, Pp 96-101 (2020)
The levels of plasma interleukin 6 and its soluble receptors were found to be elevated in subjects with cardiovascular diseases, which points to amplification of the IL-6-mediated trans-signaling pathway in cells and the development of chronic inflam
Externí odkaz:
https://doaj.org/article/9a49eab5a1b642ad9ad83db76fc9901b