Zobrazeno 1 - 10
of 38
pro vyhledávání: '"L V Krepkova"'
Autor:
G. V. Adamov, O. L. Saybel, A. N. Babenko, E. S. Melnikov, A. I. Radimich, O. Yu. Kulyak, L. V. Krepkova
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 126-137 (2024)
Introduction. The development and registration of antiviral drugs is an urgent task. Flavonoids, in particular, luteolin-7-glycoside (cinaroside, luteolin-7-O-glycoside) demonstrate high broad-spectrum antiviral activity in vitro, and the industrial
Externí odkaz:
https://doaj.org/article/575addec5020478cb344cfad64f53309
Autor:
V. V. Karabaeva, L. V. Krepkova, A. N. Babenko, V. V. Bortnikova, T. V. Fateeva, P. G. Mizina, N. S. Mikheeva, O. N. Karabaeva
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 4, Pp 169-176 (2021)
Introduction. Viral hepatitis (HV) by its socio-economic significance occupies one of the leading places in human infectious pathology, therefore, the development of fundamentally new methods of prevention, diagnosis and treatment, as well as the cre
Externí odkaz:
https://doaj.org/article/13b31762b73b46ea9ead0ecd807846e0
Autor:
V. V. Bortnikova, V. V. Karabaeva, L. V. Krepkova, P. G. Mizina, A. N. Babenko, N. S. Mikheeva, O. N. Karabaeva
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 10, Iss 3, Pp 100-104 (2021)
Introduction. The medicine "Flakozid" with hepatoprotective effect has been developed at the VILAR. The drug is presented in dosage form-tablets of 0.1 g for oral drug administrationAim. To analyze the clinical efficacy and safety of "Flakozid" thera
Externí odkaz:
https://doaj.org/article/3515b5b14288413c9ecbdf999e6216a5
Publikováno v:
Innovations and Food Safety. :58-67
Medicinal plants are a source of biologically active substances of various chemical natures. Based on the Federal state budgetary scientific institution All-Russian Scientific Research Institute of Medicinal and Aromatic Plants (FSBSI RSRIMAR), the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5366e62977a68884299811d0f2a809
https://doi.org/10.31677/2311-0651-2022-38-4-58-67
https://doi.org/10.31677/2311-0651-2022-38-4-58-67
Publikováno v:
RUDN Journal of Medicine, Vol 0, Iss 4, Pp 5-9 (2008)
The soft medicinal forms antiviral and antimicrobic action (a cream and liniment of giporamin and evkalimin 0,5% of concentration) had been elaborated. Research of chronic toxicity of a giporamin cream and evkalimin liniment is lead on rabbits of bre
Externí odkaz:
https://doaj.org/article/a80ea2b71d864f7f87141fd4f13c3882
Publikováno v:
Bulletin of Experimental Biology and Medicine. 167:479-481
Antiviral activity of a Russian drug flakozid towards infection caused by a cytopathogenic variant of hepatitis C virus in SPEV cells is studied. Flakozid is an individual natural flavonoid glycoside 7-O-β-D-glucopyranoside-8-(methyl-but)-2-enyl)-5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0dd70256c16ad35c41d69563681a708
https://doi.org/10.1007/s10517-019-04554-5
https://doi.org/10.1007/s10517-019-04554-5
Publikováno v:
Problems Of Biological, Medical And Pharmaceutical Chemistry. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5df7b2fd8b683f1c2e0bafd779ece4
https://doi.org/10.29296/25877313-2018-04-07
https://doi.org/10.29296/25877313-2018-04-07
Autor:
L. V. Krepkova, T. A. Sokol’skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 41:536-539
A preclinical study of two complex phytopreparations based on Saint-Mary thistle (Silybum marianum) extract — sibektan (possessing hepatoprotective properties) and kamadol (producing antiinflammatory action) — has been carried out on various labo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3a4964497f26786f04077c6848d6c9
https://doi.org/10.1007/s11094-008-0010-4
https://doi.org/10.1007/s11094-008-0010-4
Autor:
L. V. Krepkova, T. A. Sokol'skaya
Publikováno v:
Pharmaceutical Chemistry Journal. 41:486-488
A preclinical study of the safety of silymar, a new phytopreparation from Saint-Mary thistle (Silybum marianum) fruits possessing hepatoprotector properties, has been carried out. The parent substance exhibited low general toxicity upon a single intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25b15fe12b71cd41381146711cab554
https://doi.org/10.1007/s11094-007-0108-0
https://doi.org/10.1007/s11094-007-0108-0
Publikováno v:
Pharmaceutical Chemistry Journal. 43
New soft medicinal forms (0.5% gel and liniment) of the antiviral phytodrug hiporamin have been developed on the basis of arespol. Experimental toxicological characterization of the new preparations was carried out on Chincilla rabbits by means of ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c9f8daa25b2b4c66a2324a030ddebdf
https://doi.org/10.1007/s11094-009-0290-3
https://doi.org/10.1007/s11094-009-0290-3