Výsledky vyhledávání - "L V, Konevega"

Dynamics of Intracellular Superoxide and NO Content in Human Endotheliocytes and Carcinoma Cells after Treatment with NO Synthase Inhibitors

Autor: L. A. Noskin, L. V. Konevega, Giliano Ny

Publikováno v: Bulletin of Experimental Biology and Medicine. 149:78-81

The dynamics of intracellular levels of superoxide and NO after cell treatment with NO synthase inhibitors were studied in human cells expressing various NOS isoforms: endotheliocytes and ECV-304 (eNOS) and carcinoma cells and HeLa-G63 (iNOS). Cytome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1b012418566b98dce77d528dce2a46
https://doi.org/10.1007/s10517-010-0880-9

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Characteristics of spontaneously transformed human endothelial ECV304 cell line: II. Functional responses of ECV304 cells

Autor: E. G. Semenova, N. Ya. Gil’yano, Fedortseva Rf, L. V. Konevega

Publikováno v: Cell and Tissue Biology. 3:274-282

The functional peculiarities of spontaneously transformed human endothelial ECV304 cell line were studied to estimate its adequacy as an endothelial cell model for studying angiogenesis and signal transduction. The dependence of the proliferative act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bee0da6807f33d19b609426dee499bc3
https://doi.org/10.1134/s1990519x09030092

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[Possible mechanism of the selective action of the inhibitors of glycolysis in the endothelial cells and the human carcinoma cells in the culture]

Autor: N Y, Giliano, G N, Bondarev, L V, Konevega, L A, Noskin, E V, Zhurishkina, I B, Alchinova

Publikováno v: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (4)

It is known that the production of energy and synthesis of macromolecules in cancer cells depend on the glucose metabolism to a greater extent than in non-tumor. In this paper we carry out a comparative study of the effectiveness of the two modifiers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::608af10aef8ab327cf04aa2fe4463295
https://pubmed.ncbi.nlm.nih.gov/25980231

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[Assessing of the role superoxide, nitric oxide and redox metals in cytotoxic effect of the H2O2 and amyloid-beta-protein]

Autor: N Ya, Giliano, S I, Stepanov, L A, Noskin, E N, Arkhipova, L V, Konevega

Publikováno v: Patologicheskaia fiziologiia i eksperimental'naia terapiia. (3)

On the cells of neuroendocrine tumor of rats (line PC12) in culture was estimating of the governing mechanisms of the cytotoxicity of the oxidative stress and the role of the amyloids in increasing this stress. Using flowcytometric assessment of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c82ff342114cdec90ac6a9ee4066ea0
https://pubmed.ncbi.nlm.nih.gov/24340618

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Changes in nitric oxide and superoxide levels in human endotheliocytes and carcinoma cells after exposure to low-dose ionizing radiation

Autor: L. V. Konevega, N. Ya. Giliano, L. A. Noskin

Publikováno v: Bulletin of experimental biology and medicine. 153(4)

The exposure of HeLa G63 and ECV-304 cells to γ-rays of 137Cs as well as β-particles of 3H2O and 3H-thymidine induced changes in redox status of not only irradiated cells, but also their progeny. Increased intracellular levels of nitric oxide (NO)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7158adea289dfbee4b4f7f1b57a95d65
https://pubmed.ncbi.nlm.nih.gov/22977854

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[Immediate and delayed effects of low doses of beta-radiation in mammalian cells in culture]

Autor: N Iu, Gil'iano, L V, Konevega, L A, Noskin

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 51(6)

We have carried out the comparative examination into the efficacy of induction of NO and superoxide anion by incorporated and unincorporated sources of ionizing radiation in endotheliocytes (line ECV 304) and carcinoma cells (line HeLa G63) expressin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c81a8bffcd6fdc474aa74b5ab1e6e635
https://pubmed.ncbi.nlm.nih.gov/22384716

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[Characteristics of the spontaneously transformed human endothelial cell line ECV304. II. Functional responses of the ECV304 cells]

Autor: N Ia, Gil'iano, E G, Semenova, R F, Fedortseva, L V, Konevega

Publikováno v: Tsitologiia. 50(7)

Functional responses of the spontaneously transformed human endothelial cell line ECV304 were studied in order to asses its applicability as an endothelial cell model for studying angiogenesis and signal transduction. The dependence of proliferation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6169d904f2fc504af0101f0cd2d3ae3d
https://pubmed.ncbi.nlm.nih.gov/18771171

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[The blocking of the proliferation of the human endothelial cells in culture by beta-irradiation from internal and external sources of the radiation. S-block is induced by the 3H2O beta-particles]

Autor: N Ia, Gil'iano, L V, Konevega, S I, Stepanov, E G, Semenova, L A, Noskin

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 47(2)

Recently we shown that low doses (0.12-0.46 Gy) of (methyl-3H)-thymidine incorporated into human endothelial cells induce the accumulation cells in G2-phase of the cell cycle. The temperate doses of (1-6 Gy) gamma-rays 137Cs were less effective in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5474c67cde263b0b5f502eeb1904d970
https://pubmed.ncbi.nlm.nih.gov/17571723

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[Internal and external sources of the radiation induce the blocking of the proliferation of the human endothelial cells in culture. G2-block is induced by beta-particle 3H-thymidine and gamma-rays 137Cs]

Autor: N Ia, Gil'iano, L V, Konevega, S I, Stepanov, E G, Semenova, L A, Noskin

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 47(1)

We found that low doses (0.12-0.46Gy) of (methyl-) 3H-thymidine incorporated into human endothelial cells induce the accumulation cells in G2-phase of the cell cycle. Temperate doses of (1-6 Gy) gamma-rays 137Cs were less effective in the G2-block es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4541cb61255552d5b997bed46dfb27ef
https://pubmed.ncbi.nlm.nih.gov/17388002

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[Modification of cellular radiosensitivity by NO-synthase inhibitors]

Autor: N Ia, Gil'iano, G N, Bondarev, L V, Konevega, E G, Semenova, L A, Noskin

Publikováno v: Radiatsionnaia biologiia, radioecologiia. 45(1)

We recently reported that the treatment of V-79 and HeLa cells with nitric oxide synthase (NOS) inhibitor N-nitro-L-arginine methyl ester (L-NAME) significantly reduced the level of the radiation-induced unstable chromosome aberrations. The stereoiso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55058c41d715ff3b2b050ed841d15d63
https://pubmed.ncbi.nlm.nih.gov/15810524

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