Výsledky vyhledávání - "L V, Dergunova"

The Role of Coding and Regulatory RNAs during Acute Stress

Autor: Ivan B. Filippenkov, L. V. Dergunova

Publikováno v: Molecular Genetics, Microbiology and Virology. 35:129-133

In the modern world, various forms of stressful conditions are an important problem for human health. The prolonged stress experienced by residents of large cities can lead to a decrease in cognitive functions and cause the development of anxiety dis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40036a0a0657c3ea92a5ab3ddcbeffb4
https://doi.org/10.3103/s0891416820030027

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Neuroprotective Effects of Peptides in the Brain: Transcriptome Approach

Autor: N. F. Myasoedov, L. V. Dergunova, Ivan B. Filippenkov, Svetlana A. Limborska

Publikováno v: Biochemistry (Moscow). 85:279-287

The importance of studying the action mechanisms of drugs based on natural regulatory peptides is commonly recognized. Particular attention is paid to the peptide drugs that contribute to the restoration of brain functions after acute cerebrovascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42ab2ca9fc19fc373ace2b218f80171
https://doi.org/10.1134/s0006297920030037

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Significance of Cholesterol-Binding Motifs in ABCA1, ABCG1, and SR-B1 Structure

Autor: L. V. Dergunova, Alexander D. Dergunov, Eugeny V. Savushkin, Dmitry Litvinov

Publikováno v: The Journal of Membrane Biology. 252:41-60

ABCA1, ABCG1 transporters, and SR-B1 receptor are the major proteins involved in cholesterol efflux from cells. We superposed in silico the location of putative cholesterol (Chol)-binding motifs CRAC/CARC and CCM in human ABCA1, ABCG1, and SR-B1 with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec219a637833f603d4e0566c5baddec
https://doi.org/10.1007/s00232-018-0056-5

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HDL cholesterol is associated with PBMC expression of genes involved in HDL metabolism and atherogenesis

Autor: Svetlana A. Limborska, Ekaterina V. Bazaeva, Alexandra V. Rozhkova, Veronika G. Dmitrieva, L. V. Dergunova, Elena V. Nosova, Alexander D Dergunov

Publikováno v: J Med Biochem
Journal of Medical Biochemistry, Vol 39, Iss 3, Pp 372-383 (2020)

To reveal the association of plasma level of high density lipoprotein cholesterol (HDL-C) level with the transcript level of annotated genes in peripheral blood mononuclear cells (PBMC) and involved in HDL metabolism and atherogenesis at the absence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deef19798e8bfc13f4811b6f2ac6e761
https://europepmc.org/articles/PMC7682810/

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[The Peptide Drug ACTH(4-7)PGP (Semax) Suppresses mRNA Transcripts Encoding Proinflammatory Mediators Induced by Reversible Ischemia of the Rat Brain]

Autor: L V, Dergunova, V G, Dmitrieva, I B, Filippenkov, V V, Stavchansky, A E, Denisova, V V, Yuzhakov, L E, Sevan'kaeva, L V, Valieva, O Y, Sudarkina, L V, Gubsky, N F, Myasoedov, S A, Limborska

Publikováno v: Molekuliarnaia biologiia. 55(3)

Due to its nootropic, neuroprotective, and immunomodulatory effects, the peptide Semax is utilized in the treatment of ischemic stroke. Our earlier RNA-Seq analysis of the transcriptome in an ischemic model of transient occlusion of the middle cerebr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5d37e1625b4dd5882d5a0d2b19f62d8
https://pubmed.ncbi.nlm.nih.gov/34097675

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Denaturation of human plasma high-density lipoproteins by urea studied by apolipoprotein A-I dissociation

Autor: L. V. Dergunova, Veronika B. Baserova, Dmitry Litvinov, Alexander D. Dergunov, Elena V. Nosova, Artem A. Malkov

Publikováno v: Biochimica et biophysica acta. Molecular and cell biology of lipids. 1866(1)

We studied the mechanism of HDL denaturation with concomitant apoA-I dissociation with HDL preparations from 48 patients with a wide range of plasma HDL-C and evaluated the contribution of lipid-free apoA-I into cholesterol efflux from macrophage, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359859e99c144815bba388234fadce7f
https://pubmed.ncbi.nlm.nih.gov/32961276

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The Protective Effect of Semax in a Model of Stress-Induced Impairment of Memory and Behavior in White Rats

Autor: L. V. Dergunova, N.G. Levitskaya, N. F. Myasoedov, D. M. Manchenko, N. Yu. Glazova, E. A. Sebentsova, Svetlana A. Limborska, L. A. Andreeva

Publikováno v: Biology Bulletin. 45:394-399

The effect of acute restrained stress on cognitive functions and anxiety-like behavior in white rats has been studied; furthermore, the influence of the fragment ACTH(4–10) analog Semax on the stress effects was evaluated. It was shown that stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb217f9f5f64d9a2f69f4db0efc1e61d
https://doi.org/10.1134/s1062359018040040

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Experimental Cerebral Ischemia Affects the Expression of Circular RNA Genes of Metabotropic Glutamate Receptors mGluR3 and mGluR5 in Rat Brain

Autor: Svetlana A. Limborska, L. V. Dergunova, Vasily V. Stavchansky, Alina E. Denisova, Ivan B. Filippenkov, K. A. Ivanova

Publikováno v: Russian Journal of Bioorganic Chemistry. 44:302-309

Circular RNAs (circRNAs) are a new RNA type that show predominantly brain-specific expression pattern in mammals. Their individual representatives, acting as competitive endogenous RNAs, can bind microRNAs and contribute to the protection of function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e39597b10f9e780724bb88b792058b6f
https://doi.org/10.1134/s1068162018030044

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