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Spontaneous interictal-like activity originates in multiple areas of the CA2-CA3 region of hippocampal slices

Autor: L. V. Colom, P. Saggau

Publikováno v: Journal of Neurophysiology. 71:1574-1585

1. The sites of origin of spontaneous interictal-like epileptiform activity in hippocampal slices from guinea pig, mouse, and rat were determined. A multisite fast optical recording technique using voltage-sensitive dyes and an array of 100 photodiod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01bf14622bca5e5ede3d05a052028c2
https://doi.org/10.1152/jn.1994.71.4.1574

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Potassium (K+) channel expression in basal forebrain cholinergic neurons

Autor: L, Betancourt, L V, Colom

Publikováno v: Journal of neuroscience research. 61(6)

Basal forebrain cholinergic neurons (BFCN) are depleted early in the course of Alzheimer's disease (AD). BFCN voltage-gated K(+) channels regulate acetylcholine release and may play a role in BFCN neurodegeneration. Neuronal voltage-gated K(+) channe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::873805b8bfe975557ef23d7fa0dc0fae
https://pubmed.ncbi.nlm.nih.gov/10972961

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Increased intracellular calcium triggered by immune mechanisms in amyotrophic lateral sclerosis

Autor: S H, Appel, R G, Smith, M, Alexianu, L, Siklos, J, Engelhardt, L V, Colom, E, Stefani

Publikováno v: Clinical neuroscience (New York, N.Y.). 3(6)

Although the causes of motor neuron degeneration and death in amyotrophic lateral sclerosis (ALS) is unknown, recent evidence suggests a prominent role for increased intracellular calcium, possibly triggered by autoimmune mechanisms. The presence in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0c505a54b21c1eac60e48c3b66fbe3c1
https://pubmed.ncbi.nlm.nih.gov/9021258

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