Zobrazeno 1 - 10
of 46
pro vyhledávání: '"L T, Archer"'
Autor:
J Y, Rao, R E, Hurst, W D, Bales, P L, Jones, R A, Bass, L T, Archer, P B, Bell, G P, Hemstreet
Publikováno v:
Cancer research. 50(8)
Transformation is associated with profound structural and quantitative changes in the cytoskeleton. Herein we report studies using F-actin, a major cytoskeletal protein, as a quantitative marker for transformation cells, focusing on separating the ef
Publikováno v:
American Journal of Physiology-Legacy Content. 231:872-879
The roles of renal gluconeogenesis and glucose utilization in control, hemorrhaged, and endotoxin-injected animals were investigated using anesthetized, eviscerated, nonnephrectomized and nephrectomized dogs. Results demonstrate an increased glucose
Publikováno v:
American Journal of Physiology-Legacy Content. 228:365-368
Changes in myocardial substrate utilization were studied after experimental coronary hypotension in the isolated dog heart perfused with the blood of a large donor animal. After a control period (100 mmHg) the afterload of the isolated heart was adju
Publikováno v:
Medical Microbiology and Immunology. 175:221-227
Treatment efficacy with netilmicin sulphate/methylprednisolone sodium succinate in a severe septic shock baboon model, using an LD100 of live Escherichia coli, was evaluated. All the animals treated with both netilmicin and methylprednisolone were pe
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 23:361-365
This study was designed to document the early responses of the baboon to LD100 E. coli infusion with an emphasis on cardiovascular, respiratory, and metabolic alterations. Adult baboons were anesthetized, catheterized aseptically to monitor cardiopul
Publikováno v:
Experimental Biology and Medicine. 137:1217-1224
The question of the precise role of the heart in shock has been largely unresolved. Previous separate reports have shown that both excitatory and depressant actions on the myocardium after endotoxin are observed. The purpose of the present study was
Publikováno v:
Circulatory shock. 7(4)
Recent reports have suggested that anesthesia may weaken host defense mechanisms during shock and depress the activities of circulating leukocytes. The purpose of this study was to assay the effects of sodium pentobarbital anesthesia on glucose uptak
Publikováno v:
Advances in shock research. 10
We have documented the effectiveness of methylprednisolone sodium succinate (MPSS) and gentamicin sulfate (GS) therapy for LD100 E coli-induced shock in the baboon. We sequentially delayed initiation of MPSS infusion from 30 to 120 min and then to 24
Publikováno v:
Circulatory shock. 6(3)
The purpose of this study was to determine the effect of an extracorporeal nonanticoagulated perfusion system on survival from endotoxin shock in anesthetized closed-chest dogs. Dogs weighing approximately 18 kg were perfused four hours or used as no
Autor:
L T, Archer
Publikováno v:
Circulatory shock. 15(4)
Experimental studies have documented that myocardial dysfunction is precipitated between 3 and 6 hr after endotoxin or E. coli. This finding has now been confirmed in human septic shock. A "Hinshaw-modified" isolated working left ventricle preparatio