Zobrazeno 1 - 10
of 165
pro vyhledávání: '"L Steinhauser"'
Publikováno v:
Veterinární Medicína, Vol 66, Iss 9, Pp 369-375 (2021)
The aim of this paper was to evaluate the cadmium concentrations in the muscles, liver, and kidney of three age categories (≤ 8 months; ≤ 2 years; ≥ 2 years) of cattle during the period of years 2014-2019 and to determine the age limit at which
Externí odkaz:
https://doaj.org/article/5fc73a89296d4bf09413e09e97e29c43
Autor:
Ewa K Bomba-Warczak, Karen M Velez, Luhan T Zhou, Christelle Guillermier, Seby Edassery, Matthew L Steinhauser, Jeffrey N Savas, Francesca E Duncan
Publikováno v:
eLife, Vol 13 (2024)
The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor. We elucidated exceptionally stable proteins, structures, and macromolecules that pers
Externí odkaz:
https://doaj.org/article/6aa92de16b3c4bd9af87d1fb9f1b6b64
Autor:
Ronan C. Bracken, Lindsay M. Davison, Dennis P. Buehler, Maci E. Fulton, Emily E. Carson, Quanhu Sheng, Lindsey K. Stolze, Christelle Guillermier, Matthew L. Steinhauser, Jonathan D. Brown
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110011- (2024)
Summary: Combinatorial signaling by proinflammatory cytokines synergizes to exacerbate toxicity to cells and tissue injury during acute infections. To explore synergism at the gene-regulatory level, we investigated the dynamics of transcription and c
Externí odkaz:
https://doaj.org/article/968e40391d4f4f4f936e241935d0f84b
Autor:
Niyatie Ammanamanchi, Jessie Yester, Anita P Bargaje, Dawn Thomas, Kathryn C Little, Shannon Janzef, Kimberly Francis, Jacqueline Weinberg, Jennifer Johnson, Thomas Seery, Tyler Hutchinson Harris, Bryan J Funari, Kirsten Rose-Felker, Matthew Zinn, Susan A Miller, Shawn C West, Brian Feingold, Hairu Zhou, Matthew L Steinhauser, Timothy Csernica, Robert Michener, Bernhard Kühn
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0295651 (2024)
BackgroundWe have developed a new clinical research approach for the quantification of cellular proliferation in human infants to address unanswered questions about tissue renewal and regeneration. The approach consists of oral 15N-thymidine administ
Externí odkaz:
https://doaj.org/article/fa25fa000f8e469180c21b9ff6df5486
Autor:
Yang Zhang, Christelle Guillermier, Thomas De Raedt, Andrew G. Cox, Ophelia Maertens, Dean Yimlamai, Mingyue Lun, Adam Whitney, Richard L. Maas, Wolfram Goessling, Karen Cichowski, Matthew L. Steinhauser
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101355- (2020)
Summary: Malignant tumors exhibit high degrees of genomic heterogeneity at the cellular level, leading to the view that subpopulations of tumor cells drive growth and treatment resistance. To examine the degree to which tumors also exhibit metabolic
Externí odkaz:
https://doaj.org/article/65c606e11867455bb254d8409165dc47
Autor:
Ana Vujic, Carolin Lerchenmüller, Ting-Di Wu, Christelle Guillermier, Charles P. Rabolli, Emilia Gonzalez, Samuel E. Senyo, Xiaojun Liu, Jean-Luc Guerquin-Kern, Matthew L. Steinhauser, Richard T. Lee, Anthony Rosenzweig
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The adult mammalian heart has a limited cardiomyogenic capacity. Here the authors show that intensive exercise leads to a 4.6-fold increase in murine cardiomyocyte proliferation requiring the expression of miR-222, and that exercise induces an extend
Externí odkaz:
https://doaj.org/article/2df138bce0e446388382bb5c88daeae8
Autor:
Junjie Lu, Anna Baccei, Edroaldo Lummertz da Rocha, Christelle Guillermier, Sean McManus, Lydia A. Finney, Cheng Zhang, Matthew L. Steinhauser, Hu Li, Paul H. Lerou
Publikováno v:
Stem Cell Research, Vol 28, Iss , Pp 48-55 (2018)
Differentiation of human pluripotent stem cells towards definitive endoderm (DE) is the critical first step for generating cells comprising organs such as the gut, liver, pancreas and lung. This in-vitro differentiation process generates a heterogene
Externí odkaz:
https://doaj.org/article/e8297ed74daf4461b1d8abd072ac4c1b
Autor:
Carolin Lerchenmüller, Ana Vujic, Sonja Mittag, Annie Wang, Charles P. Rabolli, Chiara Heß, Fynn Betge, Ashraf Y. Rangrez, Malay Chaklader, Christelle Guillermier, Frank Gyngard, Jason D. Roh, Haobo Li, Matthew L. Steinhauser, Norbert Frey, Beverly Rothermel, Christoph Dieterich, Anthony Rosenzweig, Richard T. Lee
Publikováno v:
Circulation. 146:412-426
Background: The human heart has limited capacity to generate new cardiomyocytes and this capacity declines with age. Because loss of cardiomyocytes may contribute to heart failure, it is crucial to explore stimuli of endogenous cardiac regeneration t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ffaccaf2c8bd5497481031a1bf9fd0
https://doi.org/10.1161/circulationaha.121.057276
https://doi.org/10.1161/circulationaha.121.057276
Autor:
Bokai Zhu, Silvia Liu, Natalie L. David, William Dion, Nandini K Doshi, Lauren B. Siegel, Tânia Amorim, Rosemary E. Andrews, GV Naveen Kumar, Saad Irfan, Tristan Pesaresi, Ankit X. Sharma, Michelle Sun, Pouneh K. Fazeli, Matthew L. Steinhauser
Publikováno v:
bioRxiv
While circadian rhythms are entrained to the once daily light-dark cycle of the sun, many marine organisms exhibit ~12h ultradian rhythms corresponding to the twice daily movement of the tides. Although human ancestors emerged from circatidal environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0fe27a922a365ff5b17338e53e8acf
https://doi.org/10.1101/2023.05.02.539021
https://doi.org/10.1101/2023.05.02.539021
Autor:
Bradley M. Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane V.R. Hütter, William M. Oldham, Jörg Menche, Matthew L. Steinhauser, Bradley A. Maron
Publikováno v:
JCI Insight. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792d06d361bddc3eb4a74d372375567a
https://doi.org/10.1172/jci.insight.163932
https://doi.org/10.1172/jci.insight.163932