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Akademický článek
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Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 268:R536-R548
This study was designed to characterize the rat serum proteins as biomarkers of the normal aging process. Crossed immunoelectrophoresis or electroimmunodiffusion quantitation of proteins was performed in rats aged 6, 12, 24, and 30 mo. Selection of h
Autor:
Emmanuel A. Nunez, Roger Vranckx, Tréton J, M Rouaze-Romet, L. Savu, Michelle Maya, Irwin L. Flink
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1097:19-22
Thyroxine-binding globulin (TBG), the major carrier of thyroid hormones in human serum, was thought to be absent in most species, including rodents. We demonstrated recently that in fact the rat possesses a TBG gene, virtually non-expressed in young
Publikováno v:
2006 International Semiconductor Conference.
The development of miniaturised devices for genetic diagnosis is of great interest for medicine applications. In this paper, we focus on the design, the experimental technology and characterization of a new silicon micro-bio-chip for rapid testing of
Publikováno v:
The Journal of endocrinology. 142(1)
We have investigated the role of the thyroid compared with the hypophysis in the regulation of the two saturable thyroid hormone carriers of rat serum, thyroxine-binding globulin (TBG) and transthyretin (TTR). We examined, at serum and hepatic mRNA l
Thyroxine-binding globulin (TBG), the major carrier of thyroid hormones in human and murine sera, is in the rat a developmentally regulated protein, showing a large surge during post-natal growth followed by virtual disappearance in adults. Here we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0564de32356abe4105f9d3c6cd47e05
https://europepmc.org/articles/PMC1133027/
https://europepmc.org/articles/PMC1133027/
Publikováno v:
Acta medica Austriaca. 19
Thyroxine-binding globulin (TBG) is in the rat a developmentally regulated protein, actively synthesized in postnatal developing pups and in aging animals, but undetectable in adults. Experimental depletion of thyroid hormones (TH) in adults by thyro
We confirm our finding of a major development-regulated thyroxine-binding globulin (TBG) in the serum of the euthyroid mouse and investigate a number of its binding, structural and regulatory properties. Between 16 days foetal and 60 days postnatal l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d603edc83e3176fc18643348024037ce
https://europepmc.org/articles/PMC1149564/
https://europepmc.org/articles/PMC1149564/
Publikováno v:
Biochemical and biophysical research communications. 167(1)
Using a human thyroxine binding globulin (TBG) cDNA probe, we demonstrate that rat liver contains two TBG mRNA species of different length, consisting of about 1.8 Kb and 2.4 Kb respectively. Slot blot analysis of the hepatic mRNAs from rats of diffe
Akademický článek
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