Zobrazeno 1 - 10
of 194
pro vyhledávání: '"L S Wicker"'
Publikováno v:
The Journal of Immunology. 159:1835-1843
The development of autoimmune diabetes in the nonobese diabetic (NOD) mouse is under the control of multiple insulin-dependent diabetes (Idd) genes. The Idd3 gene, originally defined as a broad peak of linkage on mouse chromosome 3, was subsequently
Autor:
P. Denny, C. J. Lord, N. J. Hill, J. V. Goy, E. R. Levy, P. L. Podolin, L. B. Peterson, L. S. Wicker, J. A. Todd, P. A. Lyons
Publikováno v:
Diabetes. 46:695-700
Autor:
C M Hill, A Liu, K W Marshall, J Mayer, B Jorgensen, B Yuan, R M Cubbon, E A Nichols, L S Wicker, J B Rothbard
Publikováno v:
The Journal of Immunology. 152:2890-2898
The individual amino acid contacts responsible for peptide binding to DRB1*0101 and/or DRB1*0401 were defined using a quantitative binding assay. The differential contribution of each amino acid in two well studied T cell determinants, HA307-319 and
Autor:
L. S. Wicker, E. H. Leiter, J. A. Todd, R. J. Renjilian, E. Peterson, P. A. Fischer, P. L. Podolin, M. Zijlstra, R. Jaenisch, L. B. Peterson
Publikováno v:
Diabetes. 43:500-504
Autor:
P A, Lyons, L S, Wicker
Publikováno v:
Current directions in autoimmunity. 1
Publikováno v:
Diabetes. 50(11)
As many of the linked chromosome regions that predispose to type 1 diabetes in the NOD mouse have been dissected, it has become apparent that the initially observed effect is in fact attributable to several loci. One such cluster of loci on distal ch
Autor:
C, Ma, P E, Whiteley, P M, Cameron, D C, Freed, A, Pressey, S L, Chen, B, Garni-Wagner, C, Fang, D M, Zaller, L S, Wicker, J S, Blum
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(12)
Following antigenic challenge, MHC-restricted T cell responses are directed against a few dominant antigenic epitopes. Here, evidence is provided demonstrating the importance of APC in modulating the hierarchy of MHC class II-restricted T cell respon
Autor:
A B, Jones, J J, Acton, A D, Adams, W, Yuen, E A, Nichols, C D, Schwartz, L S, Wicker, J D, Hermes
Publikováno v:
Bioorganicmedicinal chemistry letters. 9(14)
Tetrapeptide derived major histocompatability (MHC) II ligands have been developed that contain no unadulterated peptide bonds. These are the 'least peptidic' ligands for any MHC protein yet reported.
Autor:
C. J. Lord, S. K. Bohlander, E. A. Hopes, C. T. Montague, N. J. Hill, J. -B. Prins, R. J. Renjilian, L. B. Peterson, L. S. Wicker, J. A. Todd, P. Denny
Publikováno v:
Mammalian genome : official journal of the International Mammalian Genome Society. 6(9)
Development of novel congenic mouse strains has allowed us to better define the location of the diabetogenic locus, Idd3, on Chromosome (Chr) 3. Congenic strains were identified by use of published and newly developed microsatellite markers, their ge
Publikováno v:
Transplantation proceedings. 24(3)