Breast cancer biobank from a single institutional cohort in an urban setting in india: Tumor characteristics and survival outcomes

Autor: Laleh Busheri, Santosh Dixit, Smeeta Nare, Rashmi Alhat, George Thomas, Mangal Jagtap, Ruth Navgire, Priya Shinde, Rituja Banale, Rohini Unde, Ruhi Reddy, Shahin Shaikh, Aishwarya Konnur, Namrata Namewar, Ashwini Bapat, Ankita Patil, Rateeka Johari, Roli Kushwaha, Wimpy Kumari, Beenu Varghese, Pooja Deshpande, Chetan Deshmukh, Devaki A. Kelkar, L S Shashidhara, Chaitanyanand B Koppiker, Madhura Kulkarni

Publikováno v: Cancer Treatment and Research Communications, Vol 28, Iss , Pp 100409- (2021)

Abstract: 250 words: Background: A breast cancer biobank with retrospectively collected patient data and FFPE tissue samples was established in 2018 at Prashanti Cancer Care Mission, Pune, India. It runs a cancer care clinic with support from a singl

Externí odkaz: https://doaj.org/article/77c935350f064c968d074c4d11a9d97c

Meta-Analysis of Prevalence of Triple-Negative Breast Cancer and Its Clinical Features at Incidence in Indian Patients With Breast Cancer

Autor: Chaitanyanand B. Koppiker, Nidhi Parikh, L. S. Shashidhara, Apurv Kulkarni, Devaki A. Kelkar, Madhura Kulkarni

Publikováno v: JCO Global Oncology

PURPOSE Breast cancer is the most common cancer in women in India, with higher incidence rates of aggressive subtypes, such as triple-negative breast cancer (TNBC). METHODS A systematic review was performed to compute pooled prevalence rates of TNBC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101b0fcd518abe97f647520251f0d90e
https://doi.org/10.1200/go.20.00054

Genome-Wide Screen for Context-Dependent Tumor Suppressors Identified Using in Vivo Models for Neoplasia in Drosophila

Autor: T.S. Sridhar, Rachel Paul, Devaki A. Kelkar, Aditi Khatpe, Pooja M. Vaid, Avantika Ahiya, Casper Groth, Teresa Eichenlaub, Sanket Nagarkar, Nelchi Prashali, Madhumita Chakladar, Héctor Herranz, Diana Andrejeva, Stephen M. Cohen, L. S. Shashidhara

Publikováno v: G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2999-3008 (2020)
Groth, C, Vaid, P, Khatpe, A, Prashali, N, Ahiya, A, Andrejeva, D, Chakladar, M, Nagarkar, S, Paul, R, Kelkar, D, Eichenlaub, T, Herranz, H, Sridhar, T S, Cohen, S M & Shashidhara, L S 2020, ' Genome-wide screen for context-dependent tumor suppressors identified using in vivo models for neoplasia in Drosophila ', G3: Genes, Genomes, Genetics, vol. 10, no. 9, pp. 2999-3008 . https://doi.org/10.1534/g3.120.401545

Genetic approaches in Drosophila have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer in vivo. Here, we report on large-scale RNAi-based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ebf742441edda89f5f55d846b03d20
http://europepmc.org/articles/PMC7467006

A micro-evolutionary change in target binding sites as a key determinant of Ultrabithorax function in Drosophila

Autor: Guillaume Giraud, Saurabh J. Pradhan, L. S. Shashidhara, Bleicher F, Soumen Khan, Rachel Paul, Samir Merabet

Hox genes encode Homeodomain-containing transcription factors, which specify segmental identities along the anterior-posterior axis. Functional changes in Hox genes have been directly implicated in the evolution of body plans across the metazoan line

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6847ffa53bbba29a88a3cae7b55493
https://doi.org/10.1101/2021.08.17.456507

Burden of COVID-19 and Case Fatality Rate in Pune India: An Analysis of First and Second Wave of the Pandemic

Autor: Nikhil Gupte, Aparna Joshi, Sanket Nagarkar, Vidya Mave, Prasad Bogam, L. S. Shashidhara, Joy Merwin Monteiro, Divyashri Jain

BackgroundThe recent second wave in India in April-May 2021 placed an unprecedented burden on the Indian health systems. However, limited data exist on the epidemiology of the COVID-19 pandemic from the first wave through the second wave in India. Wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ee3832c911dda67b715187935f34d46
https://doi.org/10.1101/2021.06.21.21259225