Zobrazeno 1 - 10
of 30
pro vyhledávání: '"L S Perry"'
Autor:
Robert G. Tsushima, X. Gao, M. P. Gaidhu, Robert L. S. Perry, Rolando B. Ceddia, R. Gonzalez, Suraj Unniappan
Publikováno v:
Endocrinology. 152:3628-3637
Nesfatin-1 is a recently discovered anorexigen, and we first reported nesfatin-like immunoreactivity in the pancreatic β-cells. The aim of this study was to characterize the effects of nesfatin-1 on whole-body energy homeostasis, insulin secretion,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a0db3cd4ce56fdf0adfcc55a398093
https://doi.org/10.1210/en.2010-1471
https://doi.org/10.1210/en.2010-1471
Publikováno v:
Molecular Endocrinology. 24:1434-1440
The aim of this study was to investigate the molecular mechanisms by which AMP-kinase (AMPK) activation inhibits basal and insulin-stimulated glucose uptake in primary adipocytes. Rat epididymal adipocytes were exposed to 5-aminoimidazole-4-carboxami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed384bc87f52d602f0a963eff3310a0
https://doi.org/10.1210/me.2009-0502
https://doi.org/10.1210/me.2009-0502
Autor:
C. Yang, Joseph W. Gordon, Joseph Chan, H. Ilyas, John C. McDermott, Jahan Salma, L. Naghibi, M. Marback, N. Soora, R. L. S. Perry
Publikováno v:
Molecular and Cellular Biology. 29:3355-3366
The myocyte enhancer factor 2 (MEF2) transcription factors play important roles in neuronal, cardiac, and skeletal muscle tissues. MEF2 serves as a nuclear sensor, integrating signals from several signaling cascades through protein-protein interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2061aee6824c91645378517932a780d
https://doi.org/10.1128/mcb.00227-08
https://doi.org/10.1128/mcb.00227-08
Autor:
John C. McDermott, Arif Aziz, Jianzhong Zhao, Nathaniel B. Nowacki, K. W. Michael Siu, Robert L. S. Perry, Min Du, Joseph Chan, Jahan Salma, Joseph W. Gordon
Publikováno v:
Molecular and Cellular Biology. 28:2952-2970
Activation of protein kinase A (PKA) by elevation of the intracellular cyclic AMP (cAMP) level inhibits skeletal myogenesis. Previously, an indirect modulation of the myogenic regulatory factors (MRFs) was implicated as the mechanism. Because myocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2812f6e6bd6b061fde71da955d7bee
https://doi.org/10.1128/mcb.00248-08
https://doi.org/10.1128/mcb.00248-08
Publikováno v:
Molecular and Cellular Biology. 26:6248-6260
Transforming growth factor beta1 (TGF-beta1) and myostatin signaling, mediated by the same Smad downstream effectors, potently repress skeletal muscle cell differentiation. Smad7 inhibits these cytokine signaling pathways. The role of Smad7 during sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2be2ae4bca7eb775b1d9a89785de6d
https://doi.org/10.1128/mcb.00384-06
https://doi.org/10.1128/mcb.00384-06
Autor:
Michael A. Rudnicki, Maura H Parker, Charlotte A. Berkes, Robert L. S. Perry, Mélanie C Fauteux
Publikováno v:
Molecular and Cellular Biology. 26:5771-5783
The MyoD family of basic helix-loop-helix transcription factors function as heterodimers with members of the E-protein family to induce myogenic gene activation. The E-protein HEB is alternatively spliced to generate alpha and beta isoforms. While th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f817bcbfcaad9d4b1811d1e06af690
https://doi.org/10.1128/mcb.02404-05
https://doi.org/10.1128/mcb.02404-05
Publikováno v:
The Journal of Cell Biology
MyoD and Myf5 are basic helix-loop-helix transcription factors that play key but redundant roles in specifying myogenic progenitors during embryogenesis. However, there are functional differences between the two transcription factors that impact myob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaec31eab8a1c1f2c28d0eb0bce2a66
https://doi.org/10.1083/jcb.200502101
https://doi.org/10.1083/jcb.200502101
Autor:
Robert L. S. Perry, Ronald C. Kahn, Richard Butler, Frank L. Graham, Eran R. Andrechek, William R. Hardy, William J. Muller, Michael A. Rudnicki, Adele Girgis-Gabardo
Publikováno v:
Molecular and Cellular Biology. 22:4714-4722
Signaling mediated by ErbB2 is thought to play a critical role in numerous developmental processes. However, due to the embryonic lethality associated with the germ line inactivation of erbB2, its role in adult tissues remains largely obscure. Given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181b95b4668f3e0b827fdf4b5624e8a4
https://doi.org/10.1128/mcb.22.13.4714-4722.2002
https://doi.org/10.1128/mcb.22.13.4714-4722.2002
Autor:
Michael A. Rudnicki, Andrew D. Strand, Stephen J. Tapscott, Robert L. S. Perry, Donald A. Bergstrom, Bennett H. Penn
Publikováno v:
Molecular Cell. 9(3):587-600
We used expression arrays and chromatin immunoprecipitation assays to demonstrate that myogenesis consists of discrete subprograms of gene expression regulated by MyoD. Approximately 5% of assayed genes alter expression in a specific temporal sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e152c418544bcdd3534c7c498dd8e50
Autor:
Lynn A. Megeney, Robert L. S. Perry, Boris Kablar, Michael A. Rudnicki, Chuyan Ying, Linda May
Publikováno v:
Proceedings of the National Academy of Sciences. 96:220-225
The mdx mouse, a mouse model of Duchenne muscular dystrophy, carries a loss-of-function mutation in dystrophin, a component of the membrane-associated dystrophin–glycoprotein complex. Unlike humans, mdx mice rarely display cardiac abnormalities and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04730087dcf60c219b9c08b3f94472c
https://doi.org/10.1073/pnas.96.1.220
https://doi.org/10.1073/pnas.96.1.220