Zobrazeno 1 - 10
of 23
pro vyhledávání: '"L S, Van Winkle"'
Autor:
D. M. Hyde, L. A. Miller, E. S. Schelegle, M. V. Fanucchi, L. S. Van Winkle, N. K. Tyler, M. V. Avdalovic, M. J. Evans, R. Kajekar, A. R. Buckpitt, K. E. Pinkerton, J. P. Joad, L. J. Gershwin, R. Wu, C. G. Plopper
Publikováno v:
European Respiratory Review, Vol 15, Iss 101, Pp 122-135 (2006)
Asthma is a worldwide health problem that affects 300 million people, as estimated by the World Health Organization. A key question in light of this statistic is: "what is the most appropriate laboratory animal model for human asthma?" The present au
Externí odkaz:
https://doaj.org/article/2f3c593e59aa4693bff89c6dcf3e10b1
Publikováno v:
A50. MOLECULAR MECHANISMS OF ENVIRONMENTAL AND OCCUPATIONAL LUNG DISEASES.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6e783c8cad4a99cce35255face0ba0
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1840
https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a1840
Naphthalene (NA) is a ubiquitous pollutant to which humans are widely exposed. 1,2-Dihydro-1,2-dihydroxynaphthalene (NA-dihydrodiol) is a major metabolite of NA generated by microsomal epoxide hydrolase (mEH). To investigate the role of the NA-dihydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2744098f59db7a826001e13029ac832e
https://escholarship.org/uc/item/7061n1kg
https://escholarship.org/uc/item/7061n1kg
Autor:
Ali Oender Yildirim, Heinz Fehrenbach, P. Kilb, Bernd Müller, Martina Veith, T. Rausch, L. S. Van Winkle
Publikováno v:
European Respiratory Journal. 32:694-704
Airway epithelial cells are exposed to environmental toxicants that result in airway injury. Naphthalene (NA) causes site-selective damage to Clara cells in mouse distal airways. N-terminally truncated recombinant human keratinocyte growth factor (De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4768dc251f0c1fe390bd30ac422e9044
https://doi.org/10.1183/09031936.00155107
https://doi.org/10.1183/09031936.00155107
Autor:
Mark V Avdalovic, Reen Wu, Nancy K. Tyler, C. G. Plopper, Laurel J. Gershwin, Edward S. Schelegle, Kent E. Pinkerton, D. M. Hyde, Michelle V. Fanucchi, Lisa A. Miller, Michael J. Evans, Radhika Kajekar, Alan R. Buckpitt, Jesse P. Joad, L. S. Van Winkle
Publikováno v:
European Respiratory Review. 15:122-135
Asthma is a worldwide health problem that affects 300 million people, as estimated by the World Health Organization. A key question in light of this statistic is: “what is the most appropriate laboratory animal model for human asthma?” The presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f15c8cd39314a0fdf346922e390046
https://doi.org/10.1183/09059180.00010103
https://doi.org/10.1183/09059180.00010103
Autor:
L. S. Van Winkle, Lisa A. Miller, Michael J. Evans, Laurel J. Gershwin, Susan J. Nishio, Edward S. Schelegle, Charles G. Plopper, Gregory L. Baker, Michelle V. Fanucchi, Lorraine M. Pantle, D. M. Hyde
Publikováno v:
Clinical Experimental Allergy. 34:1131-1136
Summary Background In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides farinae) caused thickening of the basement membrane zone (BMZ) and (2) HDMA+ozone (O3) caused depletion of BMZ perlecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f44c0b7c59eeb2d9b6bf93af092062
https://doi.org/10.1111/j.1365-2222.2004.02004.x
https://doi.org/10.1111/j.1365-2222.2004.02004.x
Autor:
Lisa A. Miller, Charles G. Plopper, Michael J. Evans, Nancy K. Tyler, Dallas M. Hyde, Laurel J. Gershwin, Emily M. Pieczarka, Edward S. Schelegle, L. S. Van Winkle, Joan E. Gerriets
Publikováno v:
Clinical & Experimental Allergy. 33:1686-1694
Summary Background The effect of chronic environmental aeroallergen exposure on the immune system and airways has not been experimentally defined in very young children. Objective The purpose of this study was to determine the immunophenotype of peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9a68affb7781cf9f015dac56dd6ff81
https://doi.org/10.1111/j.1365-2222.2003.01812.x
https://doi.org/10.1111/j.1365-2222.2003.01812.x
Autor:
L. S. Van Winkle, Dexter Morin, R. Baldwin, Michelle V. Fanucchi, Michael A. Shultz, Bridget C. Boland, A. Karlsson, A. Taff, K. Chan, Jay A. A. West, Alan R. Buckpitt, Charles G. Plopper, Ching-Yu Lin, Margaret A. Isbell
Publikováno v:
Drug Metabolism Reviews. 34:791-820
The lung, which is in intimate contact with the external environment, is exposed to a number of toxicants both by virtue of its large surface area and because it receives 100% of the cardiac output. Lung diseases are a major disease entity in the U.S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbca19d90ea9ba3902e64ebe940dc28e
https://doi.org/10.1081/dmr-120015694
https://doi.org/10.1081/dmr-120015694
Autor:
Alan R. Buckpitt, Susan J. Nishio, Brian K. Tarkington, Nancy K. Tyler, Laurel J. Gershwin, Michelle V. Fanucchi, W. L. Lasley, L. S. Van Winkle, Edward S. Schelegle, Mark V Avdalovic, Charles G. Plopper, Reen Wu, Kent E. Pinkerton, Jesse P. Joad, Lisa A. Miller, Michael J. Evans, Sarah M. Davis, Dallas M. Hyde
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 42(7)
The risks for infants and young children receiving inhaled corticosteroid (ICS) therapy are largely unknown. Recent clinical studies indicate that ICS therapy in pre-school children with symptoms of asthma result in decreased symptoms without influen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71d79aabc6bd908fb86547b3e3ff4f76
https://pubmed.ncbi.nlm.nih.gov/22702509
https://pubmed.ncbi.nlm.nih.gov/22702509
Exposure to air pollution has been linked to pulmonary diseases. Naphthalene (NA), an abundant polycyclic aromatic hydrocarbon in tobacco smoke and urban air, is a model toxicant for air pollution effects in the lung. Repeated exposures to NA in male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524c57bd905aca0243c77618d19b183
https://europepmc.org/articles/PMC3349371/
https://europepmc.org/articles/PMC3349371/