Zobrazeno 1 - 2
of 2
pro vyhledávání: '"L S, Richter"'
Autor:
E K, Bradley, J M, Kerr, L S, Richter, G M, Figliozzi, D A, Goff, R N, Zuckermann, D C, Spellmeyer, J M, Blaney
Publikováno v:
Molecular diversity. 3(1)
Synthesis and screening of combinatorial libraries for pharmaceutical lead discovery is a rapidly expanding field. Oligo-N-substituted glycines (NSGs) were one of the earliest sources of molecular diversity in combinatorial libraries. In one of the f
Autor:
J A, Gibbons, A A, Hancock, C R, Vitt, S, Knepper, S A, Buckner, M E, Brune, I, Milicic, J F, Kerwin, L S, Richter, E W, Taylor, K L, Spear, R N, Zuckermann, D C, Spellmeyer, R A, Braeckman, W H, Moos
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(2)
We characterize the in vitro and in vivo pharmacology of CHIR 2279, an N-substituted glycine peptoid previously identified from a combinatorial library as a novel ligand to alpha 1-adrenoceptors. Competitive receptor-binding assays with [3H]prazosin