Výsledky vyhledávání

Oxidative activation of CaMKII mediates arrhythmias and contractile dysfunction in an obstructive sleep apnea mouse model

Autor: P Hegner, M Gugg, S Lebek, L S Maier, M Arzt, S Wagner

Publikováno v: European Heart Journal. 43

Background/Introduction Atrial arrhythmias frequently occur in patients with obstructive sleep apnea (OSA), but the underlying mechanisms remain insufficiently understood. We recently demonstrated that CaMKII-dependent pro-arrhythmic activity is incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dea66fc0aba97af2171e135162950143
https://doi.org/10.1093/eurheartj/ehac544.2971

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Impact of sleep-disordered breathing on premature ventricular complexes after cardiac surgery

Autor: L Schäffer, A Hofmann, M Creutzenberg, B Flörchinger, D Camboni, C Schmid, L S Maier, S Wagner, M Arzt, M Tafelmeier

Publikováno v: 04.02 - Clinical and epidemiological respiratory sleep medicine.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b316db63af2e146774a4c17aec7dc883
https://doi.org/10.1183/13993003.congress-2022.2843

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Proarrhythmische Nebenwirkungen von Nicht-Antiarrhythmika

Autor: C G Jungbauer, L S Maier

Publikováno v: Herzschrittmachertherapie + Elektrophysiologie. 30:262-267

Eine erworbene QT-Verlangerung wird fast ausschlieslich durch eine Hemmung des Kaliumkanals Ikr verursacht. Insbesondere Patienten im Krankenhaus sind einem erhohten Risiko fur Torsade-de-pointes-Tachykardien (TdP) ausgesetzt. Bei jeder Verordnung vo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76e77500185f0f410b46557d5d3532f8
https://doi.org/10.1007/s00399-019-00635-0

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CaMKII

Autor: K G, Kreitmeier, D, Tarnowski, M S, Nanadikar, M J, Baier, S, Wagner, D M, Katschinski, L S, Maier, C M, Sag

Publikováno v: American journal of physiology. Heart and circulatory physiology. 320(3)

CaMKII is needed for the recovery of Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bd2e3dde04b86ed88c2e82eed902d836
https://pubmed.ncbi.nlm.nih.gov/33449853

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[Proarrhythmic adverse effects of nonarrhythmic drugs]

Autor: C G, Jungbauer, L S, Maier

Publikováno v: HerzschrittmachertherapieElektrophysiologie. 30(3)

Acquired QT prolongation is almost exclusively the result of inhibition of the potassium channel Ikr. Especially hospitalized patients have a high risk to suffer from Torsade de points (TdP). Therefore, any prescription of drugs with the potential fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aaefbbebc788b426fcf8057ffb9a90cf
https://pubmed.ncbi.nlm.nih.gov/31444571

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Enhanced Ca2+ influx through cardiac L-type Ca2+ channels maintains the systolic Ca2+ transient in early cardiac atrophy induced by mechanical unloading

Autor: A. P. Schwoerer, S. Neef, I. Broichhausen, J. Jacubeit, M. Tiburcy, M. Wagner, D. Biermann, M. Didié, C. Vettel, L. S. Maier, W. H. Zimmermann, L. Carrier, T. Eschenhagen, T. Volk, A. El-Armouche, H. Ehmke

Publikováno v: Pflugers Archiv

Cardiac atrophy as a consequence of mechanical unloading develops following exposure to microgravity or prolonged bed rest. It also plays a central role in the reverse remodelling induced by left ventricular unloading in patients with heart failure.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6584a80d165167974f6139b37d1d7a15
http://europepmc.org/articles/PMC3898408

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[Extracorporeal pulmonary support procedures in intensive care medicine 2014]

Autor: T, Müller, M, Lubnow, A, Philipp, M, Pfeifer, L S, Maier

Publikováno v: Der Internist. 55(11)

In recent years a rapid expansion of extracorporeal devices for support of severe lung failure has been witnessed. Systems for veno-venous extracorporeal membrane oxygenation (VV-ECMO) or for extracorporeal carbon dioxide elimination are distinguishe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::939f865aea9ec427f04a488a9960778f
https://pubmed.ncbi.nlm.nih.gov/25260398

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Influence of stimulation frequency on [Na+]i and contractile function in Langendorff-perfused rat heart

Autor: Burkert Pieske, L. S. Maier, D. G. Allen

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 273:H1246-H1254

To study the relationship between stimulation frequency and intracellular Na+ concentration ([Na+]i), Langendorff-perfused rat hearts were loaded with the Na(+)-sensitive dye sodium-binding benzofuran isophthalate (SBFI). An intracellular calibration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6528ea7012e5d6f4c2145d3716e786
https://doi.org/10.1152/ajpheart.1997.273.3.h1246

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[Pathophysiology of chronic myocardial ischemia]

Autor: C, Jacobshagen, L S, Maier

Publikováno v: Herz. 38(4)

Myocardial ischemia is caused by a mismatch between myocardial oxygen supply and myocardial oxygen requirements. Obstructive coronary artery disease (CAD) is the most common cause for myocardial ischemia. Although coronary bypass graft (CABG) surgery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93e5313ee9c97a90dfb727314b06178f
https://pubmed.ncbi.nlm.nih.gov/23604109

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