Zobrazeno 1 - 10
of 48
pro vyhledávání: '"L S, Forno"'
Publikováno v:
Experimental Neurology. 154:684-690
A specific mutation (A53T) in the encoding region for alpha-synuclein has been identified in a large multigenerational family with an autosomal dominant parkinsonism known as the Contursi kindred. In this study, we used a monoclonal antibody directed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ea76f97c78c4c31f8c62989dea64c9
https://doi.org/10.1006/exnr.1998.6975
https://doi.org/10.1006/exnr.1998.6975
Publikováno v:
Neuroscience Letters. 184:44-47
Eosinophilic neuronal inclusions resembling cortical Lewy bodies have been observed in the amygdala-parahippocampal region of aged 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys. Electron microscopy in six monkeys revealed a co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053f29b78b7178eb10642e508c7ef952
https://doi.org/10.1016/0304-3940(94)11164-e
https://doi.org/10.1016/0304-3940(94)11164-e
Autor:
Richard Mayeux, J. Ellenberg, T. Wilcox, J. W. Langston, Matthew M. Zack, Peter S. Spencer, Gustavo C. Román, J. P. Hubble, J. W. Tetrud, Christopher G. Goetz, I. Irwin, Caroline M. Tanner, William C. Koller, Leonard T. Kurland, A. J. Ruttenber, L. S. Forno, Martyn T. Smith, Lawrence I. Golbe
Publikováno v:
Neurology. 41:8-13
In this review, we attempt to evaluate the evidence that a long pre-symptomatic period occurs in PD. Much of this discussion is speculative, but we hope important in setting the context for the specific works that follow in this monograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbb12d08b4c36b47fcdfd4ffd316ce5a
https://doi.org/10.1212/wnl.41.5_suppl_2.8
https://doi.org/10.1212/wnl.41.5_suppl_2.8
Autor:
J. W. Langston, L. S. Forno
Publikováno v:
Acta Neuropathologica. 81:691-694
A 45-year-old woman with moderately severe parkinsonism underwent adrenal medullary autograft to the brain. The operation was performed in Mexico City. There were multiple post-operative complications, including worsening of the parkinsonism with alm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14c0525d6fe226f2aa0b01211949b41
https://doi.org/10.1007/bf00296383
https://doi.org/10.1007/bf00296383
Autor:
D C, Spencer, L S, Forno
Publikováno v:
Brain Pathol
Acquired (non-Wilsonian) hepatocerebral degeneration (AHCD) is an irreversible neurological condition characterized by dementia, dysarthria, and motor disturbances. It has been described in patients with severe liver disease of many causes, and notab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::997ea2f46339acce910fa126f7abe199
https://pubmed.ncbi.nlm.nih.gov/10764052
https://pubmed.ncbi.nlm.nih.gov/10764052
Publikováno v:
Annals of neurology. 46(4)
This report provides the first detailed neuropathological study of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in humans. All 3 subjects self-administered the drug under the impression it was "synthetic heroin" and subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87cb43a80e9806ff8a4f271e02cf4f88
https://pubmed.ncbi.nlm.nih.gov/10894230
https://pubmed.ncbi.nlm.nih.gov/10894230
Autor:
G M, Murphy, L S, Forno, W G, Ellis, D, Nochlin, E, Levy-Lahad, P, Poorkaj, T D, Bird, Z, Jiang, B, Cordell
Publikováno v:
The American journal of pathology. 149(6)
Mutations in the presenilin (PS)-1 and PS-2 genes have been shown to be linked with the development of Alzheimer's disease (AD). We examined Alzheimer's brain tissue by immunohistochemistry using a set of antibodies raised to sequences shared between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9509b07eefdf2c48e2bc3644c15ddbc0
https://pubmed.ncbi.nlm.nih.gov/8952521
https://pubmed.ncbi.nlm.nih.gov/8952521
Publikováno v:
The American journal of pathology. 149(2)
The presence of beta-amyloid in brain tissue is characteristic of Alzheimer's disease (AD). A naturally occurring derivative of the beta-amyloid peptide, p3, possesses all of the structural determinants required for fibril assembly and neurotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::283b1c7437ca6f0c71f2fc3edf9f9048
https://pubmed.ncbi.nlm.nih.gov/8701997
https://pubmed.ncbi.nlm.nih.gov/8701997
Publikováno v:
Advances in neurology. 69
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2800f8a8e45c021362f048a6a152d63
https://pubmed.ncbi.nlm.nih.gov/8615131
https://pubmed.ncbi.nlm.nih.gov/8615131
Autor:
I, Irwin, L E, DeLanney, T, McNeill, P, Chan, L S, Forno, G M, Murphy, D A, Di Monte, M S, Sandy, J W, Langston
Publikováno v:
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 3(4)
The present study examined neurochemical, morphological and functional markers of the nigrostriatal dopamine system in young, intermediate-aged and old squirrel monkeys. Striking reductions in motoric activity were observed with advancing age. signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cff6a9e0c6e9fb1aaa2898adb97c661
https://pubmed.ncbi.nlm.nih.gov/7531106
https://pubmed.ncbi.nlm.nih.gov/7531106