Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L S, Engel"'
Autor:
C.-T. Wang, B. H. Baek, W. Vizuete, L. S. Engel, J. Xing, J. Green, M. Serre, R. Strott, J. Bowden, J.-H. Woo
Publikováno v:
Earth System Science Data, Vol 15, Pp 5261-5279 (2023)
Styrene, benzene, toluene, ethylbenzene, and xylenes (SBTEX) are established neurotoxicants. SBTEX contains hazardous air pollutants (HAPs) that are released from the petrochemical industry, combustion process, transport emission, and solvent usage s
Externí odkaz:
https://doaj.org/article/9949cf350a6b4d9bb5baea5ca4b02caa
Autor:
Judy M. Moreau, James M. Hill, L S Engel, Michelle C. Callegan, Richard J. O'Callaghan, Timothy J. Foster, L C Green, O M Hartford
Publikováno v:
Infection and Immunity. 65:1571-1578
Staphylococcus aureus corneal infection results in extensive inflammation and tissue damage. Our previous studies of bacterial mutants have demonstrated a role for alpha-toxin in corneal virulence. This study analyzes, by genetic rescue experiments,
Publikováno v:
Infection and Immunity. 62:2478-2482
Staphylococcus aureus produces a variety of proteins, including alpha-toxin and protein A, that could contribute to corneal tissue damage during keratitis. We examined corneal infections produced by intrastromal injection of four S. aureus strains--t
Publisher Summary This chapter describes the rabbit intrastromal injection model of Pseudomonas keratitis. Typical chemotherapy experiments employ Young New Zealand white rabbits, weighing 2–3 kg. For membranectomies, a hand-held electric cauterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a94b7785b258a47a21bd0bb5989c37e
https://doi.org/10.1016/b978-012775390-4/50181-0
https://doi.org/10.1016/b978-012775390-4/50181-0
Publikováno v:
Current eye research. 17(8)
Staphylococcus aureus causes severe corneal infections that often result in corneal scarring and blindness. Presently, therapy often involves the use of a fluoroquinolone antibiotic. This study, employing an experimental rabbit model of Staphylococcu
Publikováno v:
Investigative ophthalmologyvisual science. 39(3)
A Pseudomonas mutant deficient in protease IV has significantly reduced virulence in experimental keratitis. In the present study, the corneal toxicity of purified protease IV and its ability to augment the virulence of protease-IV-deficient bacteria
Publikováno v:
Investigative ophthalmologyvisual science. 38(8)
The role of protease IV in the pathogenesis of Pseudomonas aeruginosa keratitis was investigated by comparing a mutant strain completely deficient in protease IV activity with its protease IV activity-producing parent.A protease IV-deficient Pseudomo
Publikováno v:
Investigative ophthalmologyvisual science. 37(4)
The role of exoproteins in the pathogenesis of Pseudomonas aeruginosa keratitis was investigated in three animal models by assessing the relationship between corneal virulence and the activities of exotoxin A, elastase, alkaline protease, and an unch
Autor:
L C, Green, M C, Callegan, L S, Engel, Y, Shimomura, D W, Jasheway, R J, O'Callaghan, J M, Hill
Publikováno v:
Japanese journal of ophthalmology. 40(1)
Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norf
Publikováno v:
Japanese journal of ophthalmology. 40(2)
Ciprofloxacin is a fluoroquinolone antibiotic with broad spectrum bactericidal activity. A commercially available form of ciprofloxacin contains benzalkonium chloride (BAC) (0.006%) and EDTA (0.05%) as preservatives. Since BAC has been shown to cause