A Photocrosslinking Probe to Capture the Substrates of Caseinolytic Protease P.

Autor: Gronauer TF; TUM School of Natural Sciences, Department of Biosciences, Chair of Organic Chemistry II, Center for Functional Protein Assemblies (CPA), Technical University of Munich (TUM), Ernst-Otto-Fischer-Str. 8, 85748, Garching, Germany.; Current affiliation: Metabolomics and Proteomics Core (MPC), Helmholtz Zentrum München German Research Center for Environmental Health, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany., Eck LK; TUM School of Natural Sciences, Department of Biosciences, Chair of Organic Chemistry II, Center for Functional Protein Assemblies (CPA), Technical University of Munich (TUM), Ernst-Otto-Fischer-Str. 8, 85748, Garching, Germany., Ludwig C; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), TUM School of Life Sciences, Technical University of Munich (TUM), Gregor-Mendel-Str. 4, 85354, Freising, Germany., Sieber SA; TUM School of Natural Sciences, Department of Biosciences, Chair of Organic Chemistry II, Center for Functional Protein Assemblies (CPA), Technical University of Munich (TUM), Ernst-Otto-Fischer-Str. 8, 85748, Garching, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Nov 11; Vol. 63 (46), pp. e202409220. Date of Electronic Publication: 2024 Oct 07.

Corneal virulence of Staphylococcus aureus: roles of alpha-toxin and protein A in pathogenesis

Autor: L S Engel, Michelle C. Callegan, James M. Hill, Richard J. O'Callaghan

Publikováno v: Infection and Immunity. 62:2478-2482

Staphylococcus aureus produces a variety of proteins, including alpha-toxin and protein A, that could contribute to corneal tissue damage during keratitis. We examined corneal infections produced by intrastromal injection of four S. aureus strains--t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acdf1bb3b1def52fa42b134e0d636d3
https://doi.org/10.1128/iai.62.6.2478-2482.1994

Effectiveness of ciprofloxacin-polystyrene sulfonate (PSS), ciprofloxacin and ofloxacin in a Staphylococcus keratitis model

Autor: J M, Moreau, L C, Green, L S, Engel, J M, Hill, R J, O'Callaghan

Publikováno v: Current eye research. 17(8)

Staphylococcus aureus causes severe corneal infections that often result in corneal scarring and blindness. Presently, therapy often involves the use of a fluoroquinolone antibiotic. This study, employing an experimental rabbit model of Staphylococcu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37ee2d5509c868008c831319129fe726
https://pubmed.ncbi.nlm.nih.gov/9723996

Pseudomonas deficient in protease IV has significantly reduced corneal virulence

Autor: L S, Engel, J A, Hobden, J M, Moreau, M C, Callegan, J M, Hill, R J, O'Callaghan

Publikováno v: Investigative ophthalmologyvisual science. 38(8)

The role of protease IV in the pathogenesis of Pseudomonas aeruginosa keratitis was investigated by comparing a mutant strain completely deficient in protease IV activity with its protease IV activity-producing parent.A protease IV-deficient Pseudomo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fec64ba460c57ef117e877d2f89ea710
https://pubmed.ncbi.nlm.nih.gov/9224281

Pharmacokinetics of topically applied ciprofloxacin in rabbit tears

Autor: L C, Green, M C, Callegan, L S, Engel, Y, Shimomura, D W, Jasheway, R J, O'Callaghan, J M, Hill

Publikováno v: Japanese journal of ophthalmology. 40(1)

Fluoroquinolones provide an important single antibiotic therapy for bacterial keratitis caused by Staphylococcus aureus and numerous gram-negative bacteria, including Pseudomonas aeruginosa. The pharmacokinetics of three ocular fluoroquinolones, norf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2a1aadd05062d039ad4ebb04eb78016c
https://pubmed.ncbi.nlm.nih.gov/8739510