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pro vyhledávání: '"L S, DeBruin"'
Publikováno v:
Chemical research in toxicology. 14(11)
An increased risk of breast cancer has been observed in women who consume "very well-done" meats. Heterocyclic amines are mutagenic and carcinogenic pyrolysis products formed during high temperature cooking of meats. In the present study, human milk
Publikováno v:
Chemical research in toxicology. 12(1)
Environmental chemicals may play a role in the etiology of human breast cancer. Aromatic amines, industrial chemicals found as environmental pollutants, have been identified as rat mammary carcinogens. We have detected the monocyclic aromatic amines,
Autor:
P D, Josephy, L S, DeBruin, H L, Lord, J N, Oak, D H, Evans, Z, Guo, M S, Dong, F P, Guengerich
Publikováno v:
Cancer research. 55(4)
The most widely used bioassay in genetic toxicology is the Ames test, which combines a bacterial mutagenicity assay (reversion of Salmonella typhimurium histidine-auxotrophic tester strains) with an exogenous bioactivation system (hepatic postmitocho