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Akademický článek

A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development

Autor: S. Canosa, N. Licheri, L. Bergandi, G. Gennarelli, C. Paschero, M. Beccuti, D. Cimadomo, G. Coticchio, L. Rienzi, C. Benedetto, F. Cordero, A. Revelli

Publikováno v: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-11 (2024)

Abstract Background Artificial Intelligence entails the application of computer algorithms to the huge and heterogeneous amount of morphodynamic data produced by Time-Lapse Technology. In this context, Machine Learning (ML) methods were developed in

Externí odkaz: https://doaj.org/article/15441f78ac0b41e8aaa4b13095ba94a0

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Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses

Publikováno v: Human Reproduction. 38:762-775

STUDY QUESTION Can chromosomal abnormalities beyond copy-number aneuploidies (i.e. ploidy level and microdeletions (MDs)) be detected using a preimplantation genetic testing (PGT) platform? SUMMARY ANSWER The proposed integrated approach accurately a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22f2ec413b1993e24dbc4a6868d7870b
https://doi.org/10.1093/humrep/dead033

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The role of thyroid function in female and male infertility: a narrative review

Autor: R. Mazzilli, S. Medenica, A. M. Di Tommaso, G. Fabozzi, V. Zamponi, D. Cimadomo, L. Rienzi, F. M. Ubaldi, M. Watanabe, A. Faggiano, S. La Vignera, G. Defeudis

Publikováno v: Journal of Endocrinological Investigation. 46:15-26

Purpose We herein aimed to review the new insights into the impact of impaired thyroid function on male and female fertility, spacing from spontaneous pregnancy to ART, with the objective of providing an updated narrative revision of the literature.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e78e3d85f756d2d23cbdd5f53b70b7d2
https://doi.org/10.1007/s40618-022-01883-7

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Akademický článek

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Akademický článek

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O-101 Elucidation of blastocyst collapse and its consequences: a comprehensive artificial intelligence-powered analysis of 1943 embryos from 643 couples

Autor: D Cimadomo, A Marconetto, F Innocenti, S Trio, V Chiappetta, D Soscia, L Albricci, L Dovere, A Giancani, R Maggiulli, I Erlich, A Ben-Meir, I Har-Vardi, F.M Ubaldi, L Rienzi

Publikováno v: Human Reproduction. 37

Study question What are the causes and consequences of blastocyst collapse? Summary answer ∼50% of blastocysts collapsed, especially if they are aneuploid and/or morphologically-poor. Yet, no impact on the live-birth-rate (LBR) per vitrified-warmed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40fad6dc56c6fe0e4212ad54f6ce4224
https://doi.org/10.1093/humrep/deac105.124

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P-189 Association between iDAScore v1.0, senior embryologists’ grading and euploidy in 546 blastocysts obtained during 189 PGT-A cycles

Autor: V Casciani, D Cimadomo, S Trio, V Chiappetta, F Innocenti, B Iussig, E Alviggi, S Canosa, N Barnocchi, R Maggiulli, J Berntsen, M.F Kragh, M Larman, F.M Ubaldi, L Rienzi

Publikováno v: Human Reproduction. 37

Study question Is (intelligent data analysis) iDAScore v1.0 associated with euploidy at the blastocyst stage? Summary answer iDAScore v1.0 significantly correlated with euploidy (maternal age-adjusted OR:1.3 and AUC:0.72). Euploid blastocysts were ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::978e7a1922cee1a1ed98433ac9d7256b
https://doi.org/10.1093/humrep/deac107.182

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P-442 A new option to thaw slow-frozen human ovarian tissue in cancer patients: efficacy and safety of the combination of different cryopreservation kits

Autor: S Canosa, L Parmegiani, F Evangelista, S Durando, F Salvagno, M Sestero, D Cimadomo, A Vaiarelli, L Rienzi, F.M Ubaldi, F Bongioanni, A Revelli, G Gennarelli

Publikováno v: Human Reproduction. 37

Study question Is follicular viability of slow-frozen human ovarian tissue preserved if rapid thawing is performed using a solution containing extracellular cryoprotectant only? Summary answer Follicular viability is preserved even using thawing solu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c9619a503971f4c87e08277a913586f
https://doi.org/10.1093/humrep/deac107.417

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P-389 Elevated BMI in oocyte donors or recipients is associated with a higher risk of miscarriage after blastocyst transfer: a multicenter analysis of 1544 procedures

Autor: G Fabozzi, D Cimadomo, R Maggiulli, V Badajoz, M Aura Masip, F Bongioanni, F Benini, A Degl'Innocenti, L Buffo, M Hebles Duvison, F Sànchez Martìn, P Sànchez Martìn, L Rienzi, F.M Ubaldi, J Llàcer

Publikováno v: Human Reproduction. 37

Study question Is an elevated BMI in either oocyte donors or recipients associated with a higher risk of miscarriage after blastocyst transfer? Summary answer Overweight in oocyte donors and/or obesity in recipients are associated with a 2X-higher ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c5549964093dbc6cb4b34876a7f9479
https://doi.org/10.1093/humrep/deac107.366

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