Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure

Autor: Milton Packer, John J.V. McMurray, Henry Krum, Wolfgang Kiowski, Barry M. Massie, Avi Caspi, Craig M. Pratt, Mark C. Petrie, David DeMets, Isaac Kobrin, Sebastien Roux, Karl Swedberg, Craig Pratt, Barry Massie, John McMurray, Eugene Connally, Mark Petrie, Susan Anderson, Jody Barnet, Robert Cody, Henry Dargie, Gary Francis, Barry Greenberg, Juerg Reichen, J. Karrasch, H. Krum, J. Horowitz, J. Amerena, A. Sindone, P. MacDonald, I. Jeffrey, I. Button, E. DeAngelis, R. Pacher, R. Davies, F. McAlister, P. Tanser, B. Sussex, G. Baumann, E. Fleck, H.-G. Olbrich, K. Werdan, H. Klein, F. Staffeld, A.M. Zeiher, C. Roediger, A. Caspi, A. Marmor, L. Reisin, Z. Vered, E. Klainman, N. Roguin, D. Tzivoni, D. David, B. Lewis, E. Abinader, M. Omary, Y. Rosenman, E. Kaluski, R.W. Breedveld, P.H. van der Burgh, P.H.J.M. Dunselman, H.J. Schaafsma, D.P. Hertzberger, N.J. Holwerda, J.A. Kragten, J. van Wijngaarden, J.L. Posma, S.A.M. Said, L.C. Slegers, R.M. Tjon Joe Gin, F.N. Wempe, J.C.L. Wesdorp, A.R. Willems, A.J.A.M. Withagen, J.M. Cornel, L.H.J. van Kempen, W. Kiowski, O. Bertel, T. Moccetti, J.J.V. McMurray, R.A. Greenbaum, P. Bennett, J. Swan, G. Davies, I. Findlay, B. Gould, S. Ball, P. Hubner, A. Lahiri, J. McLay, R. Northcote, S. Saltissi, I. Squire, J. Stephens, M. Stewart, G. Bridgen, J. Walsh, D.J. Webb, Z. Ansari, S. Baron, R. Bellinger, W. Bennet, D. Benvenuti, D. Dawley, L.C. Egbujiobi, I. Eisenstein, T. Little, A. Hertsberg, M. Greenspan, R.J. Grossman, P. Hanley, M. Jesrani, H. Kashou, R. Levites, R. Malik, B. Marmorstein, M. Schwartz, A. Nisar, R. Perelman, M.L. Schwarz, S. Sedlis, J. Srebro, M. Taveras, R. Weiss, P. Weitzman, G.K. Wetherley, M. El Shahawy, D. Kereiakes, L. Campos, G. Peterson, R.S. Small, W.R. Davis, M.-T. Olivari, W. Meengs, M. Koren, P. Slagona, S. Jennison, R. Hershberger, K.F. Browne, D.J. Farnham, S. Zelenkofske, C. Lawless, M. Nathan, T. Meyer, M. Kukin, H. Parekh, R. Berkowitz, J. Boehmer, S. Brozena, P. Dandona, G.W. Dec, V. DeQuattro, P. Fenster, M. Fowler, S. Ellaham, M. Geller, M. Gheorgiade, J. Ghali, S. Murali, S. Katz, C. Bott-Silverman, B. Singh, U. Thadani, G. Torre, J. Teerlink, T. Chandraratna, M. Kesselbrenner, A. Mukherjee, C. Che-Pin Tsai, K. Abbo, M. Goldberg, T. Smith, R.T. Martin

Publikováno v: JACC: Heart Failure. 5:317-326

Objectives The objective of this clinical trial was to evaluate the long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure. Background Endothelin may play a role i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb048a52ef9808b8c1bc2dbcf796ca66
https://doi.org/10.1016/j.jchf.2017.02.021

Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca 2+ -permeable nonselective cation channel

Autor: I. L. Reisin, Elsa Zotta, Silvia González-Perrett, Marisa Batelli, Keetae Kim, Peter C. Harris, Horacio F. Cantiello, Cristina Ibarra, Alicia E. Damiano, M. Amin Arnaout

Publikováno v: Proceedings of the National Academy of Sciences. 98:1182-1187

Defects in polycystin-2, a ubiquitous transmembrane glycoprotein of unknown function, is a major cause of autosomal dominant polycystic kidney disease (ADPKD), whose manifestation entails the development of fluid-filled cysts in target organs. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e9e50a5931aa43611711b64bf4275bc
https://doi.org/10.1073/pnas.98.3.1182

Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator

Autor: Claudio Grosman, Dennis A. Ausiello, George R. Jackson, I. L. Reisin, Horacio F. Cantiello, Catherine R. O'Riordan, Steven C. Borkan, A. G. Prat, Yihan Wang

Publikováno v: American Journal of Physiology-Cell Physiology. 274:C799-C809

Expression of the cystic fibrosis transmembrane conductance regulator (CFTR), and of at least one other member of the ATP-binding cassette family of transport proteins, P-glycoprotein, is associated with the electrodiffusional movement of the nucleot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1790aafdd726fb467505f8b70db689a
https://doi.org/10.1152/ajpcell.1998.274.3.c799

Cellular ATP release by the cystic fibrosis transmembrane conductance regulator

Autor: A. G. Prat, Dennis A. Ausiello, I L Reisin, Horacio F. Cantiello

Publikováno v: American Journal of Physiology-Cell Physiology. 270:C538-C545

Recent studies from our laboratory indicate that members of the ATP-binding cassette (ABC) family of transporters, including P-glycoprotein and cystic fibrosis transmembrane conductance regulator (CFTR), are ATP-permeable channels. The physiological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06faddacca61b7f62e22892535415ba0
https://doi.org/10.1152/ajpcell.1996.270.2.c538

Plasma fibrinogen levels and their correlates in 6457 coronary heart disease patients. The Bezafibrate Infarction Prevention (BIP) study

Autor: N Roguin, Shlomo Behar, L Reisin, Eran Graff, Avshalom Caspi, Uri Goldbourt, B Pelled, Eddy Barasch, Henrietta Reicher-Reiss, Michal Benderly

Publikováno v: Journal of Clinical Epidemiology. 48:757-765

The association between fibrinogen measured in healthy individuals and subsequent development of ischemic heart disease is well established, but studies reporting fibrinogen levels in coronary heart disease patients are scarce. Plasma fibrinogen was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a019ed11ac1388734e1c71c58309eaaf
https://doi.org/10.1016/0895-4356(94)00191-r