Zobrazeno 1 - 9
of 9
pro vyhledávání: '"L R Paborsky"'
Autor:
V. S. Law, C. T. Mao, Anant K. Jain, Steven Coutre, S. Y. Mejza, L. R. Paborsky, Kyla E. Dunn, Lawrence L.K. Leung, Craig S. Gibbs, S. Y. Matsumura, W. X. Li, Manuel Tsiang
Publikováno v:
Nature. 378:413-416
AT sites of vascular injury, thrombin interacts with multiple procoagulant substrates1–6 to mediate both fibrin clotting and platelet aggregation. But upon binding to thrombomodulin on the vascular endothelium, thrombin instead activates protein C,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19accbbd2a6fdd763c5ef9182f04e211
https://doi.org/10.1038/378413a0
https://doi.org/10.1038/378413a0
Publikováno v:
Journal of Biological Chemistry. 268:20808-20811
A new class of thrombin inhibitors based on sequence-specific single-stranded DNA oligonucleotides (thrombin aptamer) has recently been identified. The aptamer-binding site on thrombin was examined by a solid-phase plate binding assay and by chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc882e9eb788a176a7ab592612de3c9d
https://doi.org/10.1016/s0021-9258(19)36856-5
https://doi.org/10.1016/s0021-9258(19)36856-5
Publikováno v:
Journal of Biological Chemistry. 266:4665-4668
The possible self-association of tissue factor molecules was investigated by treating cells expressing tissue factor with bifunctional cross-linking agents. The two reagents chosen were 3,3'-dithiobis(sulfosuccinimidylpropionate) and sulfosuccinimidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::573917553c56615c7c2732a30a13280d
https://doi.org/10.1016/s0021-9258(19)67699-4
https://doi.org/10.1016/s0021-9258(19)67699-4
Publikováno v:
The Journal of biological chemistry. 268(28)
A new class of thrombin inhibitors based on sequence-specific single-stranded DNA oligonucleotides (thrombin aptamer) has recently been identified. The aptamer-binding site on thrombin was examined by a solid-phase plate binding assay and by chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cbcaa1646933be603eccac0e68cfb906
https://pubmed.ncbi.nlm.nih.gov/8407909
https://pubmed.ncbi.nlm.nih.gov/8407909
Publikováno v:
The Journal of biological chemistry. 266(32)
Full-length tissue factor (263 rTF) and three truncated forms have been expressed in human kidney 293 cells; 1) 243 rTF, which lacks the cytoplasmic tail, is fully functional in the chromogenic assay and has a specific activity comparable with that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d26d4b72f870476c0bf9032ccfbee6e9
https://pubmed.ncbi.nlm.nih.gov/1834663
https://pubmed.ncbi.nlm.nih.gov/1834663
Publikováno v:
The Journal of biological chemistry. 266(8)
The possible self-association of tissue factor molecules was investigated by treating cells expressing tissue factor with bifunctional cross-linking agents. The two reagents chosen were 3,3'-dithiobis(sulfosuccinimidylpropionate) and sulfosuccinimidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6857e197e361eb3023b42dc5213998d2
https://pubmed.ncbi.nlm.nih.gov/2002014
https://pubmed.ncbi.nlm.nih.gov/2002014
Autor:
L R, Paborsky, K M, Tate, R J, Harris, D G, Yansura, L, Band, G, McCray, C M, Gorman, D P, O'Brien, J Y, Chang, J R, Swartz
Publikováno v:
Biochemistry. 28:8072-8077
Tissue factor (TF) is a 263 amino acid membrane-bound procoagulant protein that serves as a cofactor for the serine protease factor VII (fVII). Recombinant human TF (rTF) produced in both human kidney 293 cells and Escherichia coli has been immunoaff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de3e251f66931b64cacfd19d0a1c289
https://doi.org/10.1021/bi00446a016
https://doi.org/10.1021/bi00446a016
Publikováno v:
Journal of Biological Chemistry. 261:7958-7968
We describe the polypeptide structure and some of the catalytic properties of a DNA polymerase alpha.DNA primase complex that can be prepared from KB cells by immunoaffinity purification. The procedure is based on monoclonal antibodies that were rais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::664fdfe2751754ee3410ec7e88bd7a74
https://doi.org/10.1016/s0021-9258(19)57496-8
https://doi.org/10.1016/s0021-9258(19)57496-8
Publikováno v:
The Journal of biological chemistry. 261(17)
We describe the polypeptide structure and some of the catalytic properties of a DNA polymerase alpha.DNA primase complex that can be prepared from KB cells by immunoaffinity purification. The procedure is based on monoclonal antibodies that were rais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1995c591bc794088612d74d7c4be2c1e
https://pubmed.ncbi.nlm.nih.gov/2423527
https://pubmed.ncbi.nlm.nih.gov/2423527