Zobrazeno 1 - 10
of 165
pro vyhledávání: '"L R Gooding"'
Autor:
W Huang, Ann Nordgren, G Talekar, Britt Gustafsson, David A. Ornelles, L R Gooding, F Gauffin, G Bogdanovic
Publikováno v:
British Journal of Cancer
Epidemiological evidence suggests that childhood acute lymphoblastic leukaemia (ALL) may be initiated by an in infection in utero. Adenovirus DNA was detected in 13 of 49 neonatal blood spots from ALL patients but only in 3 of 47 controls (P=0.012) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef376cd8014c3bb4b1b9af3fefd6493
https://doi.org/10.1038/sj.bjc.6603983
https://doi.org/10.1038/sj.bjc.6603983
Publikováno v:
The Journal of Immunology. 154:1707-1716
The serine protease inhibitor tosyl-argenine methyl ester inhibits TNF-induced apoptosis, suggesting that proteolysis is necessary for this response. To test this hypothesis, we asked whether protein fragmentation occurs during the death of C3HA fibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a84c9dfc76e9a6b7b77363db4821c057
https://doi.org/10.4049/jimmunol.154.4.1707
https://doi.org/10.4049/jimmunol.154.4.1707
Publikováno v:
The Journal of Immunology. 149:2114-2122
SV40 transformation of rodent fibroblasts generally produces cells that are highly sensitive to killing by activated macrophages. The cell line SV-COL-E8 (E8) is typical of SV40-transformed mouse fibroblasts in that it is readily lysed when exposed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e82ecc301738c5306f7fff027378f6c
https://doi.org/10.4049/jimmunol.149.6.2114
https://doi.org/10.4049/jimmunol.149.6.2114
Autor:
Eileen White, Peter Sabbatini, L. R. Gooding, William S. M. Wold, Michael Debbas, D. I. Kusher
Publikováno v:
Scopus-Elsevier
The adenovirus E1A and E1B proteins are required for transformation of primary rodent cells. When expressed in the absence of the 19,000-dalton (19K) E1B protein, however, the E1A proteins are acutely cytotoxic and induce host cell chromosomal DNA fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8345736c99140a9489e99e7016328f4f
https://doi.org/10.1128/mcb.12.6.2570-2580.1992
https://doi.org/10.1128/mcb.12.6.2570-2580.1992
Publikováno v:
The Journal of Immunology. 145:2925-2931
A minority of transformed cell lines are directly susceptible to lysis by TNF, whereas many cells can be made sensitive to TNF by treatment with inhibitors of protein synthesis. Other groups have shown that exposure to TNF induces in many cells a tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb63b2a98c89444a8d8ab2b7f0e1c370
https://doi.org/10.4049/jimmunol.145.9.2925
https://doi.org/10.4049/jimmunol.145.9.2925
Publikováno v:
The Journal of Immunology. 145:3080-3086
We have previously described a 14,700 m.w. protein (14.7K) encoded by the E3 region of adenovirus that prevents TNF-mediated cytolysis of adenovirus-infected C3HA mouse fibroblasts. In the studies described here we have extended our analysis of TNF c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6533aa925daa3a2775a08f6b0aab35ae
https://doi.org/10.4049/jimmunol.145.9.3080
https://doi.org/10.4049/jimmunol.145.9.3080
Autor:
S M Laster, L R Gooding
Publikováno v:
The Journal of Immunology. 144:1438-1443
Our laboratory is investigating the basis for the selective recognition of transformed cells by activated mouse macrophages. As targets we are using a panel of SV40-transformed, C3H.OL fibroblast cell lines (SV-COL) that display widely different leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae1bbd745b6ce9e12c6bb39abad56b5c
https://doi.org/10.4049/jimmunol.144.4.1438
https://doi.org/10.4049/jimmunol.144.4.1438
Autor:
T E, Sparer, L R, Gooding
Publikováno v:
Current topics in microbiology and immunology. 232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::663066770a2543e1e811bc33272c71f1
https://pubmed.ncbi.nlm.nih.gov/9557397
https://pubmed.ncbi.nlm.nih.gov/9557397
Autor:
L R, Gooding
Publikováno v:
Infectious agents and disease. 3(2-3)
Human adenoviruses are among a growing number of human, animal, and even plant viruses that encode gene products that interfere with the defense mechanisms of the host. The host mechanisms most often affected by these viral products are the innate an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::924b40186bc25e748baf50fdeee6f05c
https://pubmed.ncbi.nlm.nih.gov/7812649
https://pubmed.ncbi.nlm.nih.gov/7812649
Publikováno v:
Immunology. 73(3)
The ability of cells to resist the cytolytic actions of tumour necrosis factor (TNF) has been shown to require TNF-induced gene expression. It has been shown in some human cells that the gene encoding manganese superoxide dismutase (MnSOD), a TNF-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b29d33811561a91f4bbc9cf6ea5ed19d
https://pubmed.ncbi.nlm.nih.gov/1652554
https://pubmed.ncbi.nlm.nih.gov/1652554