Zobrazeno 1 - 10
of 10
pro vyhledávání: '"L R Covey"'
Autor:
M J Yellin, J Sinning, L R Covey, W Sherman, J J Lee, E Glickman-Nir, K C Sippel, J Rogers, A M Cleary, M Parker
Publikováno v:
The Journal of Immunology. 153:666-674
Activation-induced cell surface molecules are involved in mediating bidirectional T-B lymphocyte signaling that is important in the induction of T or B lymphocyte effector functions. In this regard, T-BAM/CD40-L is an activation-induced CD4+ T cell s
Autor:
A, Bhushan, L R, Covey
Publikováno v:
European journal of immunology. 31(2)
To understand the underlying basis for the strong IL-4- and CD154-mediated Igamma1 promoter activity in Ramos 2G6 B cells, we carried out transient transfection assays with luciferase-based constructs containing approximately 2.2 kb and 500 bp of the
Publikováno v:
Immunology. 99(1)
We report the characterization of a naturally occurring polymorphism in CD40 ligand (CD40L, CD154) expressed by activated T cells from a young female patient. This polymorphism encodes a nonconservative Gly --Arg substitution in amino acid 219 in the
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(7)
The CD154 protein (CD40 ligand), which is critical to the regulation of both humoral and cellular immune responses, is expressed transiently on the surface of activated CD4+ T cells. To determine whether control of mRNA stability contributes to the h
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(2)
The CD40:CD40 ligand (CD40L) interaction plays a critical role in T cell-dependent isotype switching. To elucidate the role of CD40 signaling in the activation of gamma germline transcription and as an extension, in targeting Cgamma regions for isoty
Autor:
S, Lederman, M J, Yellin, A M, Cleary, A, Pernis, G, Inghirami, L E, Cohn, L R, Covey, J J, Lee, P, Rothman, L, Chess
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(5)
An important component of T cell help for B lymphocyte differentiation is the contact-dependent signaling mediated by the T cell-B cell activating molecule (T-BAM/CD40-L), an activation-induced surface membrane protein on CD4+ T helper cells in lymph
Autor:
M J, Yellin, K, Sippel, G, Inghirami, L R, Covey, J J, Lee, J, Sinning, E A, Clark, L, Chess, S, Lederman
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(2)
The T-BAM/CD40-L molecule on CD4+ T cells interacts with B cell CD40 molecules to deliver contact-dependent signals that drive B cell activation and Ig secretion. Cell surface T-BAM/CD40-L expression is transient and may be closely regulated in order
Autor:
S Lederman, M J Yellin, A M Cleary, A Pernis, G Inghirami, L E Cohn, L R Covey, J J Lee, P Rothman, L Chess
An important component of T cell help for B lymphocyte differentiation is the contact-dependent signaling mediated by the T cell-B cell activating molecule (T-BAM/CD40-L), an activation-induced surface membrane protein on CD4+ T helper cells in lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0e5f003f9ca8069077e743d9bdda11
http://hdl.handle.net/2318/121846
http://hdl.handle.net/2318/121846
Autor:
T K, Blackwell, P, Ferrier, B A, Malynn, R R, Pollock, L R, Covey, H Y, Suh, L B, Heinke, G M, Fulop, R A, Phillips, G D, Yancopoulos
Publikováno v:
Current topics in microbiology and immunology. 152
Most Abelson murine leukemia virus (A-MuLV)-transformed cell lines derived from scid (severe combined immune deficient) mice actively rearrange their endogenous immunoglobulin (Ig) heavy (H), but not light (L) chain variable region genes. Such cell l
Publikováno v:
Journal of cellular physiology. 105(1)
PG19 mouse melanoma cells arrest growth when they become confluent in medium containing low concentrations of serum. Under these conditions, insulin does not stimulate DNA synthesis in the mouse melanoma cells, whereas it does in mouse embryo fibrobl