Zobrazeno 1 - 10
of 36
pro vyhledávání: '"L R Bridges"'
Autor:
Jeffrey L. Franklin, Howard C. Crawford, Kevin C. Ray, Connie J. Weaver, Stacy A. Blaine, Anna L. Means, K E Guess, Yan Song, M E Moss, Frank Revetta, L R Bridges, Robert J. Coffey, James N. Higginbotham, Mary Kay Washington
Publikováno v:
Oncogene
Pancreatic cancer remains as one of the most deadly cancers with few treatment options at late stages and little information about how it develops through earlier stages. Activating mutation of the Kras gene has been implicated in, but is not suffici
Autor:
Richard G. Feltbower, Susan Picton, Adam Glaser, Patricia A. McKinney, D. A. Crooks, L. R. Bridges
Publikováno v:
Pediatric Hematology and Oncology. 21:647-660
The authors describe the incidence and survival of 480 patients diagnosed under 30 years with a CNS tumor in Yorkshire, UK, between 1990 and 2001. The effect on survival from deprivation and other prognostic factors was examined. Young adults (aged 1
Publikováno v:
British Journal of Neurosurgery. 13:516-519
Publikováno v:
Acta Neuropathologica. 98:197-202
Widespread damage to axons in the white matter of the brain is a well-recognised consequence of non-missile head injury. This diffuse axonal injury is characterised by a gradual swelling of the axon associated with an accumulation of cellular organel
Publikováno v:
British Journal of Neurosurgery. 13:516-519
Pleomorphic xanthoastrocytomas (PXA) with malignant transformation are reported in two adult men with a long history of seizures, recent onset of neurological symptoms and superficially located, temporal lobe lesions. Although PXA is generally descri
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 81:4484-4487
We present clinical details of a patient with a 20-yr history of amennorhea, a pituitary tumor, elevated PRL levels, and initially undetectable GH. Bromocriptine failed to fully suppress PRL, and there was no tumor shrinkage. Within 7 months of start
Publikováno v:
Neuropathology and Applied Neurobiology. 22:311-316
Forty-eight astrocytic tumours were stained immunohistochemically with antibodies to the cell cycle-regulating protein, cyclin D1, and to the proliferation marker MIB1 (Ki-67) using formalin fixed paraffin embedded tissue and a microwave antigen retr
Autor:
S. Al-Sarraj, L. R. Bridges
Publikováno v:
British Journal of Neurosurgery. 10:215-220
A distinctive glial tumour in an 8-month-old child characterized by superficial location, attachment to the dura, desmoplasia and histological malignancy is described. The tumour differed from "desmoplastic cerebral astrocytoma of infancy" and "desmo
Publikováno v:
British Journal of Neurosurgery. 9:57-66
A 58-year-old male who had been diagnosed as having polymyositis was found to have a mass in the fourth ventricle. This mass showed features of an inflammatory pseudotumour. This lesion has been described in many parts of the body including the centr
Autor:
L. R. Bridges, S. Al-Sarraj
Publikováno v:
British Journal of Neurosurgery. 9:143-150
p53 is a putative tumour suppressor gene implicated in a wide range of human malignancies. Mutation of p53 gene results in a more stable product and increased quantities of p53 protein in the cell. Thus, unlike the normal situation, mutated p53 is de