Zobrazeno 1 - 10
of 45
pro vyhledávání: '"L R, Pohl"'
Publikováno v:
Journal of Biological Chemistry. 266:18415-18418
Antibodies raised against halothane metabolite adducts cross-react with S-(1,1,2,2-tetrafluoroethyl)-L-cysteine (TFEC) and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine metabolite adducts. Using these antibodies in immunohistochemical experiments, met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24123bcef80578ad150aedac119d829
https://doi.org/10.1016/s0021-9258(18)55074-2
https://doi.org/10.1016/s0021-9258(18)55074-2
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(2)
Sulfonamide antimicrobials cause a delayed-onset, hypersensitivity-type syndrome characterized by fever, skin rash and multiorgan toxicity occurring 7 to 14 days after initiation of therapy. The pathogenesis is believed to be immune-mediated. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a35943dc5e52c76a20794ab7ef3f3b01
https://pubmed.ncbi.nlm.nih.gov/9262376
https://pubmed.ncbi.nlm.nih.gov/9262376
Autor:
H R, Amouzadeh, L R, Pohl
Publikováno v:
Hepatology (Baltimore, Md.). 22(3)
In this study we have investigated the mechanism of the processing of trifluoroacetylated liver microsomal protein antigens associated with halothane hepatitis to learn how the immune system might come in contact with these proteins to form antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3682b79d61a31b003a82fa16bbdf218
https://pubmed.ncbi.nlm.nih.gov/7657302
https://pubmed.ncbi.nlm.nih.gov/7657302
Publikováno v:
Arthritis and rheumatism. 37(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9c5be66b457f444ee64d9cc8f9cf9b3
https://pubmed.ncbi.nlm.nih.gov/7945484
https://pubmed.ncbi.nlm.nih.gov/7945484
Autor:
J L, Martin, D A, Dubbink, D J, Plevak, A, Peronne, H F, Taswell, E J, Hay, N R, Pumford, L R, Pohl
Publikováno v:
Anesthesia and analgesia. 74(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68c07c7bb3413d4778fd9875a3b9985e
https://pubmed.ncbi.nlm.nih.gov/1554130
https://pubmed.ncbi.nlm.nih.gov/1554130
Publikováno v:
The Journal of biological chemistry. 266(28)
Antibodies raised against halothane metabolite adducts cross-react with S-(1,1,2,2-tetrafluoroethyl)-L-cysteine (TFEC) and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine metabolite adducts. Using these antibodies in immunohistochemical experiments, met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c1d7cecb9a99062feee5947740c9b95
https://pubmed.ncbi.nlm.nih.gov/1917965
https://pubmed.ncbi.nlm.nih.gov/1917965
Publikováno v:
The Journal of biological chemistry. 266(5)
The reductive debromination of BrCCl3 by ferrous deoxymyoglobin leads to the covalent bonding of the prosthetic heme to the protein. We have previously shown, by the use of peptide mapping and mass spectrometry, that histidine residue 93 is covalentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4eb6763522f093ffa4800a641b85908c
https://pubmed.ncbi.nlm.nih.gov/1993694
https://pubmed.ncbi.nlm.nih.gov/1993694
Autor:
L R, Pohl, D, Thomassen, N R, Pumford, L E, Butler, H, Satoh, V J, Ferrans, A, Perrone, B M, Martin, J L, Martin
Publikováno v:
Advances in experimental medicine and biology. 283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42b6374edfba3c21ff33da620321be66
https://pubmed.ncbi.nlm.nih.gov/2068977
https://pubmed.ncbi.nlm.nih.gov/2068977
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(5)
Previous studies have shown that antibodies in the sera of halothane hepatitis patients recognize trifluoroacetylated liver microsomal proteins (neoantigens) of 100 kDa, 76 kDa, 59 kDa, 57 kDa, and 54 kDa. In the present investigation, factors that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1704c4d2b1da8c61ab264f635251b332
https://pubmed.ncbi.nlm.nih.gov/1981738
https://pubmed.ncbi.nlm.nih.gov/1981738
Autor:
Y, Osawa, B M, Martin, P R, Griffin, J R, Yates, J, Shabanowitz, D F, Hunt, A C, Murphy, L, Chen, R J, Cotter, L R, Pohl
Publikováno v:
The Journal of biological chemistry. 265(18)
The reductive metabolism of BrCCl3 by ferrous myoglobin leads to the alteration of the prosthetic heme to form products that can be dissociated from the protein and to those that are irreversibly bound to the protein. The major dissociable or soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab1c1103bbb7f4a8ce9dca73d782738b
https://pubmed.ncbi.nlm.nih.gov/2355004
https://pubmed.ncbi.nlm.nih.gov/2355004