Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L R, Fodero"'
Autor:
L R, Fodero, S S, Mok, D, Losic, L L, Martin, M I, Aguilar, C J, Barrow, B G, Livett, D H, Small
Publikováno v:
Journal of neurochemistry. 88(5)
The beta-amyloid protein (Abeta) is the major protein component of amyloid plaques found in the Alzheimer brain. Although there is a loss of acetylcholinesterase (AChE) from both cholinergic and non-cholinergic neurones in the brain of Alzheimer pati
Autor:
J, Sáez-Valero, L R, Fodero, M, Sjögren, N, Andreasen, S, Amici, V, Gallai, H, Vanderstichele, E, Vanmechelen, L, Parnetti, K, Blennow, D H, Small
Publikováno v:
Journal of neuroscience research. 72(4)
The identification of biochemical markers of Alzheimer's disease (AD) may help in the diagnosis of the disease. Previous studies have shown that Abeta(1-42) is decreased, and tau and phospho-tau are increased in AD cerebrospinal fluid (CSF). Our own
Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid
Publikováno v:
Journal of neurochemistry. 79(5)
A number of biomarkers (e.g. Abeta, tau) has been identified in Alzheimer's disease CSF. However, none fulfils the criteria of sensitivity and specificity (80%) needed for the development of an accurate diagnostic test. The lack of a suitable marker