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pro vyhledávání: '"L R, Finger"'
Publikováno v:
Leukemia. 7(8)
In B-precursor acute lymphoblastic leukemia (ALL), the nucleotide sequence of the complementarity determining region III (CDRIII) in the rearranged immunoglobulin heavy chain gene (IgH) has been used as a molecular fingerprint to identify the leukemi
Publikováno v:
Blood. 79(1)
The presence of multiple VHDJH joinings in upwards of 30% of acute lymphoblastic leukemias (ALL) suggests a relative instability of the rearranged immunoglobulin heavy chain (IgH) gene, but the mechanisms involved are not completely understood. An in
Autor:
Z A, Arlin, E J, Feldman, L R, Finger, T, Ahmed, A, Mittelman, P, Cook, C, Puccio, P, Baskind, P, Arnold, E D, Razis
Publikováno v:
Leukemia. 5(8)
Mitoxantrone is effective in the treatment of acute myelogenous leukemia and, in combination with either vincristine-prednisone or cytarabine (HiDAc), it is also effective in acute lymphoblastic leukemia (ALL). As mitoxantrone exhibits a steep dose-r
Publikováno v:
Cancer research. 50(17)
Early relapse and minimal residual disease during clinical remission was examined in two patients having acute T-cell leukemia/lymphoma with the t(10;14)(q24;q11) chromosomal translocation. Molecular probes which can detect T-cell receptor alpha/delt
Publikováno v:
Proceedings of the National Academy of Sciences. 85:3052-3056
We have cloned the translocation-associated and homologous normal MYC alleles from SKW-3, a leukemia T-cell line with the t(8;14)(q24;q11) translocation, and determined the sequence of the MYC oncogene first exon and flanking 5' putative regulatory r
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 86(11)
The T-cell receptor (TCR) alpha/delta chain locus on chromosome 14q11 is nonrandomly involved in translocations and inversions in human T-cell neoplasms. We have analyzed three acute T-lymphoblastic leukemia samples carrying a t(10;14)(q24;q11) chrom