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pro vyhledávání: '"L R, DePass"'
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 17(3)
A battery of mutagenicity tests was performed with nafarelin, an agonist analogue of luteinizing hormone releasing hormone (LHRH) containing tryptophan (Trp) and histidine (His). Included were the Ames assay and the gene conversion assay with yeast s
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 7(4)
To assess the possible effects of ethylene glycol (EG) on reproductive performance and mutagenesis, three-generation reproduction and dominant lethal mutagenesis studies were performed in the Fischer 344 rat. EG was included in the diet at approximat
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 4(4)
The dermal oncogenic potential of ethylenediamine (EDA) was assessed by applying 25 microliter of a 1% solution in deionized water to the skin of 50 male C3H/HeJ mice. This was the highest concentration not producing irritation or weight changes in a
Publikováno v:
Drug and chemical toxicology. 6(1)
In the subchronic study acrylic acid was incorporated in the drinking water of Fischer 344 rats (15 per group) for three months at dosage levels of 0.75, 0.25, 0.083 or 0 g/kg/day. No deaths occurred during the study but several treatment-related eff
Autor:
L R, Depass, M D, Morris
Publikováno v:
Cancer biochemistry biophysics. 5(2)
Dietary feedback control (DFC) of hepatic cholesterol synthesis is absent in hepatomas of trout, mouse, rat and man. DFC has also been shown to be defective in rats fed several liver carcinogens, including 2-acetylaminofluorene (AAF). These studies h
Publikováno v:
Developments in toxicology and environmental science. 10
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 7(2)
The carcinogenic potential of Athabasca tar sands and six experimental liquids derived from crude bitumen was evaluated utilizing the mouse epidermal carcinogenesis model. Tar sands, bitumen, and untreated naphtha produced few, if any, tumors. Three
Autor:
L R, Depass, M D, Morris
Publikováno v:
Cancer biochemistry biophysics. 6(1)
Dietary feedback control (DFC) of hepatic cholesterol synthesis is absent or defective in hepatomas of trout, mouse, rat and man. DFC has also been shown to be defective in rats fed several liver carcinogens including 2-acetylaminofluorene (AAF). The
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 7(4)
These studies were performed to assess the chronic toxicity and oncogenicity of ethylene glycol (EG) in rats and mice. Groups of 130 Fischer 344 rats and 80 CD-1 mice per sex were fed diets yielding approximate dosages of 1.0, 0.2, or 0.04 g/kg/day o
Dermal sensitization study in hairless guinea pigs with dinitrochlorobenzene and ethyl aminobenzoate
Publikováno v:
Journal of Toxicology -- Cutaneous & Ocular Toxicology; 1988, Vol. 7 Issue 4, p273, 0p