Výsledky vyhledávání

Reduced basal macrovascular and microvascular cerebral blood flow in young adults with metabolic syndrome: potential mechanisms

Autor: Katrina J. Carter, Aaron T. Ward, J. Mikhail Kellawan, John W. Harrell, Garrett L. Peltonen, Grant S. Roberts, Awni Al-Subu, Scott A. Hagen, Ronald C. Serlin, Marlowe Eldridge, Oliver Wieben, William G. Schrage

Publikováno v: Journal of Applied Physiology.

90 million Americans suffer metabolic syndrome (MetSyn), increasing risk of diabetes and poor brain outcomes including neuropathology linked to lower cerebral blood flow (CBF)-predominantly in anterior regions. We tested the hypothesis total and regi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e1528b43ab749406defaa5f3874e67d
https://doi.org/10.1152/japplphysiol.00688.2022

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Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase

Autor: Katrina J. Carter, Jaqueline K. Limberg, Rebecca E. Johansson, John W Harrell, Joshua J. Sebranek, Garrett L. Peltonen, Benjamin J. Walker, Marlowe W. Eldridge, William G. Schrage, J. Mikhail Kellawan

Publikováno v: Am J Physiol Heart Circ Physiol

Central adiposity is associated with greater sympathetic support of blood pressure. β-adrenergic receptors (β-AR) buffer sympathetically mediated vasoconstriction and β-AR-mediated vasodilation is attenuated in preclinical models of obesity. With

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8e09b1715c554d28626853121bf47f
https://doi.org/10.1152/ajpheart.00449.2021

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Akademický článek

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Akademický článek

Concurrent Beet Juice and Carbohydrate Ingestion: Influence on Glucose Tolerance in Obese and Nonobese Adults

Autor: Joseph W. Beals, Scott E. Binns, Janelle L. Davis, Gregory R. Giordano, Anna L. Klochak, Hunter L. Paris, Melani M. Schweder, Garrett L. Peltonen, Rebecca L. Scalzo, Christopher Bell

Publikováno v: Journal of Nutrition and Metabolism, Vol 2017 (2017)

Insulin resistance and obesity are characterized by low nitric oxide (NO) bioavailability. Insulin sensitivity is improved with stimulation of NO generating pathways. Consumption of dietary nitrate (NO3-) increases NO formation, via NO3- reduction to

Externí odkaz: https://doaj.org/article/eebb4b934aba450d9b8428ff347251bf

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Differential contribution of cyclooxygenase to basal cerebral blood flow and hypoxic cerebral vasodilation

Autor: John W. Harrell, Garrett L. Peltonen, Oliver Wieben, J. Mikhail Kellawan, William G. Schrage, Alejandro Roldán-Alzate

Publikováno v: Am J Physiol Regul Integr Comp Physiol

Cyclooxygenase (COX) is proposed to regulate cerebral blood flow (CBF); however, accurate regional contributions of COX are relatively unknown at baseline and particularly during hypoxia. We hypothesized that COX contributes to both basal and hypoxic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c26107805f6a524d9f6ac632597e0c
https://doi.org/10.1152/ajpregu.00132.2019

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Regulators of human white adipose browning: evidence for sympathetic control and sexual dimorphic responses to sprint interval training.

Autor: Rebecca L Scalzo, Garrett L Peltonen, Gregory R Giordano, Scott E Binns, Anna L Klochak, Hunter L R Paris, Melani M Schweder, Steve E Szallar, Lacey M Wood, Dennis G Larson, Gary J Luckasen, Matthew S Hickey, Christopher Bell

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e90696 (2014)

The conversion of white adipose to the highly thermogenic beige adipose tissue has been proposed as a potential strategy to counter the unfavorable consequences of obesity. Three regulators of this conversion have recently emerged but information reg

Externí odkaz: https://doaj.org/article/cb8f97111e11446a8470c00bb7170982

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Akademický článek

Seasonal Affective Disorder and Serotonin-Related Polymorphisms

Autor: C. Johansson, C. Smedh, T. Partonen, P. Pekkarinen, T. Paunio, J. Ekholm, L. Peltonen, D. Lichtermann, J. Palmgren, R. Adolfsson, M. Schalling

Publikováno v: Neurobiology of Disease, Vol 8, Iss 2, Pp 351-357 (2001)

Disturbances in central serotonergic systems have been hypothesized to be involved in seasonal affective disorder (SAD). Association between SAD and the shorter allele of the serotonin transporter promoter repeat length polymorphism (5-HTTLPR) has be

Externí odkaz: https://doaj.org/article/4057a528be704f8d92c6019c8d39a830

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