Zobrazeno 1 - 10
of 359
pro vyhledávání: '"L Payen"'
Autor:
Viridiane Gratpain, Axelle Loriot, Pauline Bottemanne, Ludovic d’Auria, Romano Terrasi, Valéry L. Payen, Vincent van Pesch, Giulio G. Muccioli, Anne des Rieux
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27025- (2024)
Neuro-inflammation occurs in numerous disorders such as multiple sclerosis, Alzheimer's disease and Parkinson's disease. However, anti-inflammatory drugs for the central nervous system have failed to show significant improvement when compared to a pl
Externí odkaz:
https://doaj.org/article/6e81f85a5fa34f1895470616e09b52da
Publikováno v:
Molecular Metabolism, Vol 33, Iss , Pp 48-66 (2020)
Background: Tumors are highly plastic metabolic entities composed of cancer and host cells that can adopt different metabolic phenotypes. For energy production, cancer cells may use 4 main fuels that are shuttled in 5 different metabolic pathways. Gl
Externí odkaz:
https://doaj.org/article/af34ec82d1024457a88b84628c5e446e
Autor:
Valéry L. Payen, Arnaud Lavergne, Niki Alevra Sarika, Megan Colonval, Latifa Karim, Manon Deckers, Mustapha Najimi, Wouter Coppieters, Benoît Charloteaux, Etienne M. Sokal, Adil El Taghdouini
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100278- (2021)
Background & Aims: The multiple vital functions of the human liver are performed by highly specialised parenchymal and non-parenchymal cells organised in complex collaborative sinusoidal units. Although crucial for homeostasis, the cellular make-up o
Externí odkaz:
https://doaj.org/article/dba9693007174f0d8a6f05b5c1adca53
Autor:
Sabrina Contino, Nuria Suelves, Céline Vrancx, Devkee M. Vadukul, Valery L. Payen, Serena Stanga, Luc Bertrand, Pascal Kienlen-Campard
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Presenilin 1 (PS1) and Presenilin 2 (PS2) are predominantly known as the catalytic subunits of the γ-secretase complex that generates the amyloid-β (Aβ) peptide, the major constituent of the senile plaques found in the brain of Alzheimer's disease
Externí odkaz:
https://doaj.org/article/b607f326c9de489090109092167bf221
Autor:
Pierre Sonveaux, Paolo E. Porporato, Caroline Bouzin, Thibaut Vazeille, Elisabeth Wyart, Kristin S. Rädecke, Myriam Y. Hsu, Valéry L. Payen
Supplementary Figures provide additional evidence that MCT1 silencing decreases SiHa cell migration (Fig. S1), MCT1 silencing induces intracellular acidification in SiHa cancer cells (Fig. S2), Pharmacological MCT1 inhibition decreases lactic acid ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210c3d2f7d5cf261fadcbe5b8d65bed4
https://doi.org/10.1158/0008-5472.22414281.v1
https://doi.org/10.1158/0008-5472.22414281.v1
Autor:
Pierre Sonveaux, Paolo E. Porporato, Caroline Bouzin, Thibaut Vazeille, Elisabeth Wyart, Kristin S. Rädecke, Myriam Y. Hsu, Valéry L. Payen
Extracellular acidosis resulting from intense metabolic activities in tumors promotes cancer cell migration, invasion, and metastasis. Although host cells die at low extracellular pH, cancer cells resist, as they are well equipped with transporters a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3067ea57ab01fa65dfec2fce447f731
https://doi.org/10.1158/0008-5472.c.6508932.v1
https://doi.org/10.1158/0008-5472.c.6508932.v1
Akademický článek
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Autor:
Niki Alevra Sarika, Valéry L. Payen, Maximilien Fléron, Joachim Ravau, Davide Brusa, Mustapha Najimi, Edwin De Pauw, Gauthier Eppe, Gabriel Mazzucchelli, Etienne M. Sokal, Anne des Rieux, Adil El Taghdouini
Publikováno v:
Cells, Vol 9, Iss 6, p 1357 (2020)
The lack of robust methods to preserve, purify and in vitro maintain the phenotype of the human liver’s highly specialized parenchymal and non-parenchymal cell types importantly hampers their exploitation for the development of research and clinica
Externí odkaz:
https://doaj.org/article/f090be8d1fc34fab9b13f13685419d5c
(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice
Autor:
Valéry L. Payen, Paolo E. Porporato, Pierre Danhier, Thibaut Vazeille, Marine C. N. M. Blackman, Bronislav H. May, Paul Niebes, Pierre Sonveaux
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Metastasis is of dismal prognosis for cancer patients, but recent evidence in mouse models of cancer shows that metastasis prevention is a reachable clinical objective. These experiments indicate that altered mitochondrial activities are associated w
Externí odkaz:
https://doaj.org/article/95937ccc660d4c6ea0b21d3801978ffd
Autor:
Paolo E. Porporato, Valéry L. Payen, Jhudit Pérez-Escuredo, Christophe J. De Saedeleer, Pierre Danhier, Tamara Copetti, Suveera Dhup, Morgane Tardy, Thibaut Vazeille, Caroline Bouzin, Olivier Feron, Carine Michiels, Bernard Gallez, Pierre Sonveaux
Publikováno v:
Cell Reports, Vol 8, Iss 3, Pp 754-766 (2014)
Metastatic progression of cancer is associated with poor outcome, and here we examine metabolic changes underlying this process. Although aerobic glycolysis is known to promote metastasis, we have now identified a different switch primarily affecting
Externí odkaz:
https://doaj.org/article/6374a044c672496fbe49b5ef7133ff74