Zobrazeno 1 - 10
of 28
pro vyhledávání: '"L P, Kasi"'
Autor:
Panayiotis J. Asimacopoulos, L. P. Kasi, David J. Yang, Dimitrios Andreopoulos, William C. Cole, Satish G. Jhingran, E. Edmund Kim
Publikováno v:
Nuclear Medicine and Biology. 29:185-190
We describe a method by which endocytosis-based radiolabeling of WBC is achieved using 99m Tc-liposomes of optimal size and charge, and of a composition that assures both in vitro (whole blood) and intracellular stability of the radiopharmaceutical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452f6afb29d061af8c2020093b0d279a
https://doi.org/10.1016/s0969-8051(01)00299-2
https://doi.org/10.1016/s0969-8051(01)00299-2
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 126:161-167
Purpose: The majority of patients with germ cell tumors are cured by multimodality therapy that consists of cisplatin-based chemotherapy and/or surgical resection. Serum tumor markers and conventional radiographs are utilized to stratify patients int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa68beb43b5c92d8c6dcf80113a41d7
https://doi.org/10.1007/s004320050026
https://doi.org/10.1007/s004320050026
Autor:
Sirisriro R, V. A. Bhadkamkar, L. P. Kasi, Euishin E. Kim, Donald A. Podoloff, Yehuda Z. Patt, R. smith, T. P. Haynie, Steven A. Curley, James L. Murray
Publikováno v:
Nuclear Medicine Communications. 17:568-576
The aims of this study were to evaluate the efficacy of scintigraphy with the 99 Tc m -labelled anti-carcinoembryonic antigen (CEA) monoclonal antibody Fab' fragment (IMMU4) in the diagnosis of recurrent colorectal carcinoma and to investigate its us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa7a3df59c89355f7873679094c7d61
https://doi.org/10.1097/00006231-199607000-00006
https://doi.org/10.1097/00006231-199607000-00006
Autor:
Joan E. Cunningham, James L. Murray, Steven A. Curley, Hannah Brewer, James C. Chan, Michael G. Rosenblum, David C. Hohn, Mark Roh, Donald A. Podoloff, Hua-Zhong Zhang, William E. Fogler, Lora Thompson, Carl M. Pinsky, Viju Bhadkamkar, L. P. Kasi
Publikováno v:
Cancer. 73:850-857
Background. Previous studies in the literature have suggested that radiolabeled F(ab') 2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::950d97defa68262e9299a7d7f58c4739
https://doi.org/10.1002/1097-0142(19940201)73:3+<850::aid-cncr2820731316>3.0.co
https://doi.org/10.1002/1097-0142(19940201)73:3+<850::aid-cncr2820731316>3.0.co
Autor:
V. A. Bhadkamkar, Hua‐Zhong ‐Z Zhang, Joan E. Cunningham, Donald A. Podoloff, L. P. Kasi, Daniel J. Macey, James L. Murray, Paula Trahan Rieger, Michael G. Rosenblum, Jeffrey Schlom
Publikováno v:
Cancer. 73:1057-1066
Background. Radiolabeled CC49, a second generation high affinity monoclonal antibody (MoAb) reactive with tumor-associated glycoprotein 72 (TAG72) has undergone previous Phase I testing in patients with colon cancer. Based on this report, the authors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9f41f1ffac21441e1119fd53641801
https://doi.org/10.1002/1097-0142(19940201)73:3+<1057::aid-cncr2820731345>3.0.co
https://doi.org/10.1002/1097-0142(19940201)73:3+<1057::aid-cncr2820731345>3.0.co
Autor:
James L. Murray, L. P. Kasi, Kalpana Mujoo, Robert S. Benjamin, Herbert A. Fritsche, Alexander Zukiwski, Donald A. Podoloff, Hannah Brewer, Joan E. Cunningham, V. A. Bhadkamkar
Publikováno v:
Journal of Clinical Oncology. 12:184-193
PURPOSE The purpose of this phase I trial was to determine the toxicity and maximum-tolerated dose (MTD) of murine monoclonal antibody (Mab) 14G2a (anti-GD2) in cancer patients. PATIENTS AND METHODS Following tracer doses of iodine-131-labeled 14G2a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1e848b024ebf89ee413714f173b322
https://doi.org/10.1200/jco.1994.12.1.184
https://doi.org/10.1200/jco.1994.12.1.184
Publikováno v:
Radiology. 176:691-694
In an effort to improve hepatic uptake of liposomes for drug delivery, empty vesicles were administered by means of selective arterial infusion. Negatively charged, multilamellar liposomes were labeled with technetium-99m and infused into healthy adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaab6380639e4916fdd5ca6aaace8ad1
https://doi.org/10.1148/radiology.176.3.2389028
https://doi.org/10.1148/radiology.176.3.2389028
Autor:
L P Kasi, D Andreopoulos
Publikováno v:
Journal of microencapsulation. 14(4)
The uniquely structured diphytanoylphosphatidylcholine (DphPC) forms liposomes more stable than conventional straight chain phospholipids. In this study DphPC and pegylated DphPC (DphPC-PEG) liposomes were radiolabelled and evaluated in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7b25eeef5c49e658a3c35d6f10ba0f
https://pubmed.ncbi.nlm.nih.gov/9229342
https://pubmed.ncbi.nlm.nih.gov/9229342
Autor:
J L, Murray, D J, Macey, E J, Grant, M G, Rosenblum, L P, Kasi, H Z, Zhang, R L, Katz, P T, Riger, D, LeBherz, V, Bhadkamkar
Publikováno v:
Cancer research. 55
The IFNs, alpha and gamma, have been shown to enhance the tumor-associated glycoprotein (TAG-72) on adenocarcinoma cells in vitro and in mice with human breast cancer xenografts, resulting in improved targeting of monoclonal antibody CC49. To determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fabd687a832e57baa664b2e84a01ca1
https://pubmed.ncbi.nlm.nih.gov/7493372
https://pubmed.ncbi.nlm.nih.gov/7493372
Autor:
J E, Bayouth, D J, Macey, L P, Kasi, J R, Garlich, K, McMillan, M A, Dimopoulos, R E, Champlin
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 36(5)
In this Phase I clinical trial, six multiple myeloma patients who had not responded to conventional therapy and were scheduled for bone marrow transplantation received a bone-seeking radiopharmaceutical for bone marrow ablation. The pharmacokinetics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2201900e4e4d7706b3c7fac6d749f238
https://pubmed.ncbi.nlm.nih.gov/7738641
https://pubmed.ncbi.nlm.nih.gov/7738641