Zobrazeno 1 - 10
of 43
pro vyhledávání: '"L P, Balant"'
Publikováno v:
Clinical Pharmacokinetics. 25:217-236
Psychosis is a generic term covering (for the purposes of the present article)) schizophrenia, brief reactive psychoses and manic episodes. Traditionally, research has focused on the effect of antipsychotic agents on positive or productive symptoms s
Publikováno v:
Therapeutic Drug Monitoring. 14:119-124
The purpose of the present study was to investigate whether the metabolism of clomipramine is altered by chronic alcohol drinking. Eleven recently detoxified alcoholic patients were included (experimental group EG) and compared to a reference group o
Autor:
L. P. Balant
Publikováno v:
European Journal of Clinical Pharmacology. 40:123-126
After evaluation of the present definitions in a set of particular cases, it was agreed that there was no need for “more precise” definitions and that the current ones were adequate in the majority of cases. However, it was felt that the present
Autor:
M. Gex-fabry, L. P. Balant
Publikováno v:
Xenobiotica. 20:1241-1257
1. The different types of models are described, with emphasis on the clearance-based one-compartment model, and on full physiological models which distinguish between a number of anatomical compartments interconnected through the body fluid system. 2
Publikováno v:
Therapie. 51(4)
The present study investigates the potential of therapeutic drug monitoring databases to document co-medication as a possible risk factor for subtherapeutic or excessively high concentrations of psychotropic drugs. Exposure was defined with respect t
Publikováno v:
Therapie. 51(4)
Pharmacokinetic/pharmacodynamic population approaches aim at establishing relationships between dose, drug concentration of active principles and clinical response, accounting for factors responsible for inter-individual variability. Additional diffi
Publikováno v:
Pharmacopsychiatry. 29(1)
An 83-year-old patient suffering from a depressive episode was treated with a combination of clomipramine and fluoxetine. As no marked improvement was observed and cardiac side-effects were observed, a blood sample was taken for therapeutic drug moni
Publikováno v:
Pharmaceutical research. 12(11)
Gentamicin eye drop solutions have a short precorneal residence time. The present study investigates the effect of gentamicin using a new long acting delivery Bioadhesive Ophthalmic Insert (BODI) in healthy dogs and rabbits and compares the results w
Autor:
A, Marzo, L P, Balant
Publikováno v:
Arzneimittel-Forschung. 45(2)
This paper reviews study procedures for bioequivalence trials, mainly addressed to the New Drug Application (NDA) of generic drugs, strictly referring to EU and USA guidelines on this matter. Specific attention is devoted to the most appropriate expe
Publikováno v:
Bollettino chimico farmaceutico. 133(9)