Zobrazeno 1 - 10
of 92
pro vyhledávání: '"L Owen-Schaub"'
Publikováno v:
APOPTOSIS. 8:315-325
Apoptosis plays a critical role in the development and progression of ultraviolet-induced skin cancers. In particular, Fas and Fas ligand (FasL) interactions are known to control the development of “sunburn cells” or apoptotic keratinocytes in th
Publikováno v:
The Journal of Immunology. 154:5114-5120
The carcinogenic potential of UV radiation (the primary cause of nonmelanoma skin cancer) is associated with its ability to suppress cell-mediated immune responses. Previous studies have shown that this UV-induced immune suppression is caused by the
Publikováno v:
Apoptosis : an international journal on programmed cell death. 8(4)
Apoptosis plays a critical role in the development and progression of ultraviolet-induced skin cancers. In particular, Fas and Fas ligand (FasL) interactions are known to control the development of "sunburn cells" or apoptotic keratinocytes in the UV
Autor:
L, Owen-Schaub
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
Publikováno v:
International journal of oncology. 17(1)
Apoptosis has been implicated in tumor development and progression. Fas (CD95) and Fas ligand (FasL) are an interacting receptor ligand pair that elicits apoptosis in many cell types. Although originally described as proteins regulating peripheral im
Autor:
M. F. Okcu, Elizabeth A. Grimm, Antonio C. Buzaid, M. I. Colome-Grimmer, L. Owen-Schaub, Suhendan Ekmekcioglu
Publikováno v:
Melanoma research. 9(3)
Fas ligand (FasL), a cell surface molecule belonging to the tumour necrosis factor family, binds to its receptor Fas and thus induces apoptosis of Fas-bearing cells such as activated lymphocytes. In this paper, we report the expression of FasL on mel
Publikováno v:
Hematology and cell therapy. 39(2)
CD95(FAS/Apo-1) belongs to the family of TNF receptor related molecules and is expressed on many benign and malignant types of cells. CD95 triggering is involved in the apoptotic death of lymphoid cells and may also be important in myelopoiesis. Myel
Publikováno v:
Leukemia. 10(9)
Soluble receptors have been identified for most members of the TNF-receptor/NGF receptor superfamily. CD95 (Fas/Apo-1) is of particular importance, since its triggering may induce apoptosis in sensitive cells. Recently, a soluble form of the CD95 mol
Publikováno v:
Lymphokine and cytokine research. 13(1)
Tumor necrosis factor (TNF) induces dose-dependent, but incomplete cytotoxicity in ME-180 cervical carcinoma cells resulting in a significant reduction in cell viability. In this cell line there exists a characteristic residual tumor cell population
Autor:
B B, Aggarwal, P K, Gadhia, V L, Hopwood, B J, Dave, S, Risin, L, Owen-Schaub, R, Pandita, S, Pathak
Publikováno v:
Lymphokine and cytokine research. 12(1)
We have previously reported the isolation of the cytotoxic factors, tumor necrosis factor-alpha (TNF-alpha), from monocytes and lymphotoxin or TNF-beta, from an established human B lymphoblastoid cell line. In the current study, we examined the produ