Zobrazeno 1 - 10
of 618
pro vyhledávání: '"L Odom"'
Autor:
Marcelo dos Santos Voltani Lorena, Estela Kato dos Santos, Renato Ferretti, G. A. Nagana Gowda, Guy L. Odom, Jeffrey S. Chamberlain, Cintia Yuri Matsumura
Publikováno v:
Skeletal Muscle, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Background Duchenne muscular dystrophy (DMD) is a severe form of muscular dystrophy without an effective treatment, caused by mutations in the DMD gene, leading to the absence of dystrophin. DMD results in muscle weakness, loss of ambulation
Externí odkaz:
https://doaj.org/article/bee194a80f0f4dbb94252899775bccf4
Autor:
Arden B. Piepho, Jeovanna Lowe, Laurel R. Cumby, Lisa E. Dorn, Dana M. Lake, Neha Rastogi, Megan D. Gertzen, Sarah L. Sturgill, Guy L. Odom, Mark T. Ziolo, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 344-354 (2023)
Micro-dystrophin gene replacement therapies for Duchenne muscular dystrophy (DMD) are currently in clinical trials, but have not been thoroughly investigated for their efficacy on cardiomyopathy progression to heart failure. We previously validated F
Externí odkaz:
https://doaj.org/article/112376132c914e0588ee19091b2c6a91
Autor:
Kady Lyons, Christine N. Bedore, Aaron B. Carlisle, Lauren Moniz, Timothy L. Odom, Rokeya Ahmed, Stephen E. Greiman, Ryan M. Freedman
Publikováno v:
Fishes, Vol 9, Iss 1, p 34 (2024)
Comparing co-occurring species may provide insights into how aspects of ecology may play a role in influencing their microbial communities. During the 2019 commercial shrimp trawl season off coastal Georgia, swabs of skin, gills, cloaca, and gut were
Externí odkaz:
https://doaj.org/article/c32f007023f8434789775f0afbe2c0eb
Publikováno v:
Frontiers in Education, Vol 7 (2022)
This multiple case study investigated a peer-based intervention and instruction (PBII) for social play, Play Time/Social Time (PT/ST), in four inclusive Swedish preschools. PT/ST contains 28 learning activities where children playfully practice six s
Externí odkaz:
https://doaj.org/article/b4fe483f85cf44cc817fe151b8e3724b
Identifying factors related to poverty that affect infants, toddlers, and their families, this book describes promising early child care and intervention practices specifically tailored to these children and families'needs. Leading authorities from m
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100344- (2022)
Catalyst optimization has been greatly aided over the years by methods of characterizing donor and steric properties of ligands. Here, we investigated a vanadium model system, NV(NH2)2L, to determine if the enthalpic barriers associated with amide ro
Externí odkaz:
https://doaj.org/article/a8da9510df164a888859976633edbe31
Autor:
Stephen C. Kolwicz, Jr., PhD, John K. Hall, PhD, Farid Moussavi-Harami, MD, Xiolan Chen, PhD, Stephen D. Hauschka, PhD, Jeffrey S. Chamberlain, PhD, Michael Regnier, PhD, Guy L. Odom, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 778-791 (2019)
Summary: Mutations in the gene encoding for dystrophin leads to structural and functional deterioration of cardiomyocytes and is a hallmark of cardiomyopathy in Duchenne muscular dystrophy (DMD) patients. Administration of recombinant adeno-associate
Externí odkaz:
https://doaj.org/article/4212bb9493db490e828183607656df25
Autor:
Zachary M. Howard, Lisa E. Dorn, Jeovanna Lowe, Megan D. Gertzen, Pierce Ciccone, Neha Rastogi, Guy L. Odom, Federica Accornero, Jeffrey S. Chamberlain, Jill A. Rafael-Fortney
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Gene replacement for Duchenne muscular dystrophy (DMD) with micro-dystrophins has entered clinical trials, but efficacy in preventing heart failure is unknown. Although most patients with DMD die from heart failure, cardiomyopathy is undetectable unt
Externí odkaz:
https://doaj.org/article/edf8afa3bfcf4133a3ecce62112683f8
Autor:
Rashmi Jena, Florian Benner, Francis Delano, Daniel Holmes, John McCracken, Selvan Demir, Aaron L. Odom
Publikováno v:
Chemical Science. 14:4257-4264
A room temperature stable Y(ii)bis(amide) has been prepared and fully characterized. The complex reacts with tert-butylisocyanide to make a rare example of a transition metal isocyanide, CN–Y(NHAr*)2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::896ba039aaefa10365381ed59df90c27
https://doi.org/10.1039/d3sc00171g
https://doi.org/10.1039/d3sc00171g
Autor:
Zhilin Hou, Lizbeth Lockwood, Di Zhang, Christopher J. Occhiuto, Linqing Mo, Kelly E. Aldrich, Hayden E. Stoub, Kathleen A. Gallo, Karen T. Liby, Aaron L. Odom
Publikováno v:
RSC Medicinal Chemistry. 14:74-84
SAR on NRF2 inhibitor MSU38225 has led to a compound that inhibits expression of NRF2 target genes, reduces proliferation of lung cancer cells through G2/M arrest, and lowers cell migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d2c7ef46dbd6bb13d4a8a841fe4508a
https://doi.org/10.1039/d2md00211f
https://doi.org/10.1039/d2md00211f