Zobrazeno 1 - 10
of 22
pro vyhledávání: '"L O, Whiteley"'
Autor:
Matthew Z. Dieter, Lois D. Lehman-McKeeman, L. O. Whiteley, Jeffrey D. Vassallo, Sarah M. Hicks, Andrew S. Fix, Cindy L. Lewis
Publikováno v:
Toxicology. 187:217-228
Immunohistochemical methods have been widely used to determine the histogenesis of spontaneous and chemically-induced mouse lung tumors. Typically, antigens for either alveolar Type II cells or bronchiolar epithelial Clara cells are studied. In the p
Publikováno v:
Digestive Diseases and Sciences. 46:1367-1380
The effects of fiber on colon cancer are controversial. Twenty 5-week old C57BL/6J Apc Min/+ mice were fed for 60 days with a commercial mouse diet (Teklad LM-485) and eight semidefined diets containing 5-10% various fibers and 20% soybean oil. Ten a
Autor:
David M. Klurfeld, L. O. Whiteley
Publikováno v:
Nutrition and Cancer. 36:131-149
Alterations in cell proliferation of the colon have been observed as a result of changes in amount and type of dietary fiber and in relation to risk of developing colon cancer. Although some human observational and intervention studies contribute to
Autor:
Fred M. Tatum, Robert E. Briggs, Shih-Ling Hsuan, Samuel K. Maheswaran, Srinand Sreevatsan, Emile S Zehr, L. O. Whiteley, Trevor R. Ames
Publikováno v:
Microbial Pathogenesis. 24:37-46
Allelic replacement was used to generate two isogenic lktA deletion mutants of Pasteurella haemolytica serotype 1 that were incapable of synthesizing leukotoxin (Lkt). Southern blot data confirmed that lktA sequences were absent in the two P. haemoly
Publikováno v:
Digestive Diseases and Sciences. 41:1458-1467
The dose-response relationship among dietary fiber, colonic fermentation, fecal weight, and mucosal growth were evaluated in this study. The morphometric parameter of total mucosal volume was used to assess diet-induced differences in colonic mucosal
Publikováno v:
Toxicologic Pathology. 24:305-314
The colonic mucosa can adapt its growth to alterations in diet. Metabolites from colonic microflora are frequently implicated as the primary factor in mediating the colonic mucosal response to diet; however, there is also evidence indicating that die
Autor:
Shyamala Maheswaran, Han Sang Yoo, E.L. Townsend, B W Lee, Mathur S. Kannan, Douglas J. Weiss, L. O. Whiteley, K.R. Reddy
Publikováno v:
Infection and Immunity. 61:2618-2625
In this study, we used an in vitro coculture system to determine which virulence factor from Pasteurella haemolytica A1 was responsible for augmenting bovine polymorphonuclear neutrophil (PMN)-mediated killing of bovine pulmonary artery endothelial c
Publikováno v:
Journal of Veterinary Internal Medicine. 6:11-22
The severe fibrinonecrotic pneumonia associated with pneumonic pasteurellosis usually results from colonization of the lower respiratory tract by Pasteurella haemolytica biotype A, serotype 1(A1). Despite recent research efforts, the authors lack a d
Publikováno v:
Veterinary Pathology. 28:275-285
Eighteen male Holstein calves were divided into groups of three and inoculated intratracheally with 5 x 109 logarithmic phase or ultraviolet light-killed Pasteurella haemolytica biotype A serotype 1. Serial coagulation profiles were done on one calf
Publikováno v:
Journal of Comparative Pathology. 104:23-32
Endotoxin or leucotoxin derived from Pasteurella haemolytica biotype A serotype 1 or saline was deposited by fibreoptic bronchoscopy into the caudal segment of the right anterior lung lobe of calves, and the lesions were characterized by light and tr