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Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells

Autor: T, Prueksaritanont, L M, Gorham, J H, Hochman, L O, Tran, K P, Vyas

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 24(6)

Drug-metabolizing enzymes were studied in subcellular fractions of dog, monkey, and human small intestines, and in the human adenocarcinoma cell line Caco-2, a commonly used in vitro absorption model. Immunoblot analysis indicated the presence of enz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efc1428a2d33c07df26c786eff9040fa
https://pubmed.ncbi.nlm.nih.gov/8781778

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