Výsledky vyhledávání - "L N, Porokhovnik"

Akademický článek

Allelic Variants of NRF2 and TLR9 Genes in Critical Illness

Autor: A. G. Chumachenko, A. E. Myazin, A. N. Kuzovlev, A. M. Gaponov, A. V. Tutelyan, L. N. Porokhovnik, A. M. Golubev, V. M. Pisarev

Publikováno v: Общая реаниматология, Vol 12, Iss 4, Pp 8-23 (2016)

Aim of the study. To elucidate the association of allelic variants of single nucleotide polymorphism in NRF2 (rs6726395, 177238501A>G) and TLR9 (rs352162, 52218953T>C) genes, each gene separately and in their combination, with peculiarities of the co

Externí odkaz: https://doaj.org/article/46930b109e95467c878d8577f0374c5f

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Dosage effects of human ribosomal genes (rDNA) in health and disease

Autor: N A Lyapunova, L N Porokhovnik

Publikováno v: Chromosome Research. 27:5-17

Human ribosomal RNA genes encoding a pre-transcript of the three major ribosomal RNA (18S, 5.8S, and 28S rRNA) are tandemly repeated in human genome. Their total copy number varies from 250 to 670 per diploid genome with a mean of approximately 420 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dfd5a1d17ae929e5ab03f02c642357
https://doi.org/10.1007/s10577-018-9587-y

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Association of polymorphisms in NFE2L2 gene encoding transcription factor Nrf2 with multifactorial diseases

Autor: L. N. Porokhovnik, V. M. Pisarev

Publikováno v: Russian Journal of Genetics. 53:851-864

Protein transcription factor Nrf2 is a master regulator of cytoprotection. Nrf2 launches the expression of more than 100 genes of antioxidant protection and xenobiotic detoxification under oxidative stress conditions. The effect of Nrf2 induction is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9a04935443eafc48497dca1883b2977
https://doi.org/10.1134/s1022795417080051

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[Oxidative stress, rRNA genes, and antioxidant enzymes in pathogenesis of schizophrenia and autism: modeling and clinical advices]

Autor: L N, Porokhovnik, V P, Pasekov, N A, Egolina, T G, Tsvetkova, N V, Kosiakova, N L, Gorbachevskaia, N K, Sukhotina, G V, Kozlovskaia, A B, Sorokin, N Iu, Korovina, N A, Liapunova

Publikováno v: Zhurnal obshchei biologii. 74(5)

Ribosomal genes (RG), or genes for rRNA, are represented by multiple tandem repeats in eukaryotic genomes, and just a part of them is transcriptionally active. The quantity of active copies is a stable genome feature which determines the cell's capab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e41b257c73587debb04f6e24993f37b
https://pubmed.ncbi.nlm.nih.gov/25438566

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[Cluster size polymorphism of active human ribosomal genes and simulation of the conditions of its stability through generations]

Autor: L N, Porokhovnik, V V, Viktorov, N A, Egolina, T G, Tsvetkova, N A, Lipunova

Publikováno v: Genetika. 47(12)

Based on selective silver nitrate staining of active ribosomal gene (AcRG) clusters in nucleolus organizer regions (NORs) of human metaphase chromosomes, a technique was developed earlier to estimate the AcRG dosage in individual genomes as a sum of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60ee7d7cfa168883ff61e4981e51815d
https://pubmed.ncbi.nlm.nih.gov/22384695

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Akademický článek

Self‐Propelled Proteomotors with Active Cell‐Free mtDNA Clearance for Enhanced Therapy of Sepsis‐Associated Acute Lung Injury.

Autor: Huang, Weichang^1,2 (AUTHOR), Wen, Lihong³ (AUTHOR), Tian, Hao² (AUTHOR), Jiang, Jiamiao² (AUTHOR), Liu, Meihuan² (AUTHOR), Ye, Yicheng² (AUTHOR), Gao, Junbin² (AUTHOR), Zhang, Ruotian² (AUTHOR), Wang, Fei² (AUTHOR), Li, Huaan² (AUTHOR), Shen, Lihan¹ (AUTHOR) shenlihan@hotmail.com, Peng, Fei⁴ (AUTHOR) pengf26@mail.sysu.edu.cn, Tu, Yingfeng² (AUTHOR) tuyingfeng1@smu.edu.cn

Publikováno v: Advanced Science. Sep2023, Vol. 10 Issue 27, p1-16. 16p.

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