Zobrazeno 1 - 10
of 25
pro vyhledávání: '"L Michael Thomas"'
Autor:
Xiaotian Zhong, Jennifer Schenk, Paul Sakorafas, John Chamberland, Amy Tam, L. Michael Thomas, Grace Yan, Aaron M. D’ Antona, Laura Lin, Malgorzata Nocula-Lugowska, Yan Zhang, Eric Sousa, Justin Cohen, Ling Gu, Molica Abel, Jacob Donahue, Sean Lim, Caryl Meade, Jing Zhou, Logan Riegel, Alex Birch, Brian J. Fennell, Edward Franklin, Jose M. Gomes, Boriana Tzvetkova, John J. Scarcelli
Publikováno v:
Journal of Biotechnology. 360:79-91
This study has employed mammalian transient expression systems to generate afucosylated antibodies and antibody Fc mutants for rapid candidate screening in discovery and early development. While chemical treatment with the fucose analogue 2-fluoro-pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a3270f0ecbe896963fd255d3531385
https://doi.org/10.1016/j.jbiotec.2022.10.016
https://doi.org/10.1016/j.jbiotec.2022.10.016
Autor:
Gunjan Arora, Geoffrey T Hart, Javier Manzella-Lapeira, Justin YA Doritchamou, David L Narum, L Michael Thomas, Joseph Brzostowski, Sumati Rajagopalan, Ogobara K Doumbo, Boubacar Traore, Louis H Miller, Susan K Pierce, Patrick E Duffy, Peter D Crompton, Sanjay A Desai, Eric O Long
Publikováno v:
eLife, Vol 7 (2018)
Antibodies acquired naturally through repeated exposure to Plasmodium falciparum are essential in the control of blood-stage malaria. Antibody-dependent functions may include neutralization of parasite–host interactions, complement activation, and
Externí odkaz:
https://doaj.org/article/457a8813d81c4843847f41ab69e26c6a
Autor:
Gema Romera-Cárdenas, L Michael Thomas, Sheila Lopez-Cobo, Eva M García-Cuesta, Eric O Long, Hugh T Reyburn
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150998 (2016)
Natural killer cells are cytotoxic lymphocytes important in immune responses to cancer and multiple pathogens. However, chronic activation of NK cells can induce a hyporesponsive state. The molecular basis of the mechanisms underlying the generation
Externí odkaz:
https://doaj.org/article/35c23bda3b1e43f7bf23c6f2a9fa6788
Publikováno v:
ImmunoHorizons. 4:415-419
Dendritic cells (DCs) play a key role in the initiation of an immune response and are known as “professional” APCs because of their ability to activate naive T cells. A widely used method to generate DCs in vitro is to culture bone marrow (BM) ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::019eb93788e61ebc934d947768663e54
https://doi.org/10.4049/immunohorizons.2000011
https://doi.org/10.4049/immunohorizons.2000011
Autor:
Kaveh, Abdi, L Michael, Thomas, Karen, Laky, Mehrnoosh, Abshari, Polly, Matzinger, Eric O, Long
Publikováno v:
Immunohorizons
Dendritic cells (DCs) play a key role in the initiation of an immune response and are known as “professional” antigen-presenting cells because of their ability to activate naïve T cells. A widely used method to generate DCs in vitro is to cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa77b2357dba01afefa33c53dac90244
https://pubmed.ncbi.nlm.nih.gov/32665300
https://pubmed.ncbi.nlm.nih.gov/32665300
Autor:
Geoffrey T. Hart, Javier Manzella-Lapeira, Eric O. Long, L. Michael Thomas, Gunjan Arora, Sumati Rajagopalan, Peter D. Crompton, David L. Narum, Susan K. Pierce, Ogobara K. Doumbo, Justin Doritchamou, Joseph Brzostowski, Sanjay A. Desai, Patrick E. Duffy, Louis H. Miller, Boubacar Traore
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Antibodies acquired naturally through repeated exposure to Plasmodium falciparum are essential in the control of blood-stage malaria. Antibody-dependent functions may include neutralization of parasite–host interactions, complement activation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771cb7f23b6d1acbbf6e6adb6af7e564
https://doi.org/10.7554/elife.36806
https://doi.org/10.7554/elife.36806
Autor:
Javier Manzella-Lapeira, Ogobara K. Doumbo, Justin Ya Doritchamou, Sanjay A. Desai, Boubacar Traore, Gunjan Arora, Susan K. Pierce, Geoffrey T. Hart, Peter D. Crompton, Eric O. Long, Sumati Rajagopalan, Louis H. Miller, David L. Narum, Patrick E. Duffy, L. Michael Thomas, Joseph Brzostowski
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518f24da05dad617d654746413afbea3
https://doi.org/10.7554/elife.36806.017
https://doi.org/10.7554/elife.36806.017
Autor:
Eric O. Long, Ogobara K. Doumbo, Boubacar Traore, Sanjay A. Desai, Peter D. Crompton, Louis H. Miller, Joseph Brzostowski, Geoffrey T. Hart, David L. Narum, Justin Doritchamou, Gunjan Arora, Patrick E. Duffy, Susan K. Pierce, L. Michael Thomas, Javier Manzella-Lapeira, Sumati Rajagopalan
Antibodies acquired naturally through repeated exposure to Plasmodium falciparum are essential in the control of blood-stage malaria. Antibody-dependent functions may include neutralization of parasite–host interactions, complement activation, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60f4b5396206fb362fc8adbd8a76bb5
https://doi.org/10.1101/291336
https://doi.org/10.1101/291336
Autor:
L. Michael Thomas
Publikováno v:
Immunotargets and Therapy
Natural killer (NK) cells are regulated through the coordinated functions of activating and inhibitory receptors. These receptors can act during the initial engagement of an NK cell with a target cell, or in subsequent NK cell engagements to maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f1124108bbdb31989f4a04738871a7
http://europepmc.org/articles/PMC4918248
http://europepmc.org/articles/PMC4918248
Autor:
L. Michael Thomas, Russell D. Salter
Publikováno v:
The Journal of Immunology. 185:3740-3749
ATP-mediated activation of the purinergic receptor P2X7 elicits morphological changes and proinflammatory responses in macrophages. These changes include rapid shedding of microvesicles (MV) and the nonconventional secretion of cytokines, such as IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e069b264e5dad6c0e94042377579af28
https://doi.org/10.4049/jimmunol.1001231
https://doi.org/10.4049/jimmunol.1001231