Zobrazeno 1 - 10
of 1 172
pro vyhledávání: '"L McMahon"'
Autor:
Alen Senanian, Sridhar Prabhu, Vladimir Kremenetski, Saswata Roy, Yingkang Cao, Jeremy Kline, Tatsuhiro Onodera, Logan G. Wright, Xiaodi Wu, Valla Fatemi, Peter L. McMahon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Quantum reservoir computing (QRC) has been proposed as a paradigm for performing machine learning with quantum processors where the training takes place in the classical domain, avoiding the issue of barren plateaus in parameterized-circuit
Externí odkaz:
https://doaj.org/article/1f9ad954968f4210b6b235dca912ea81
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract GABAergic transmission is influenced by post-translational modifications, like phosphorylation, impacting channel conductance, allosteric modulator sensitivity, and membrane trafficking. O-GlcNAcylation is a post-translational modification i
Externí odkaz:
https://doaj.org/article/6d10e83a3dbe49aa970d984711869502
Autor:
Caesar M. Hernandez, Macy A. McCuiston, Kristian Davis, Yolanda Halls, Juan Pablo Carcamo Dal Zotto, Nateka L. Jackson, Lynn E. Dobrunz, Peter H. King, Lori L. McMahon
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 39, Iss , Pp 100798- (2024)
In addition to extracellular amyloid plaques, intracellular neurofibrillary tau tangles, and inflammation, cognitive and emotional affect perturbations are characteristic of Alzheimer's disease (AD). The cognitive and emotional domains impaired by AD
Externí odkaz:
https://doaj.org/article/504715aab0ea482fa47c628f92a6648d
Autor:
Kh Tohidul Islam, Shenjun Zhong, Parisa Zakavi, Zhifeng Chen, Helen Kavnoudias, Shawna Farquharson, Gail Durbridge, Markus Barth, Katie L. McMahon, Paul M. Parizel, Andrew Dwyer, Gary F. Egan, Meng Law, Zhaolin Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Low-field portable magnetic resonance imaging (MRI) scanners are more accessible, cost-effective, sustainable with lower carbon emissions than superconducting high-field MRI scanners. However, the images produced have relatively poor image q
Externí odkaz:
https://doaj.org/article/937d604cfa09437591ccf58d2157a56f
Autor:
Nadeeka Dissanayaka, Dana Pourzinal, Gerard J. Byrne, Jihyun Yang, Katie L. McMahon, Gregory M. Pontone, John D. O’Sullivan, Robert Adam, Roberta Littleford, Mark Chatfield, Alexander Lehn, Zoltan Mari, Arnold Bakker
Publikováno v:
Pilot and Feasibility Studies, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Background Mild memory impairment, termed amnestic mild cognitive impairment (aMCI), is associated with rapid progression towards dementia in Parkinson’s disease (PD). Studies have shown hyperactivation of hippocampal DG/CA3 subfields duri
Externí odkaz:
https://doaj.org/article/da02d8fc97b74e9f8b6de68ff3a52ecc
Autor:
Dana Pourzinal, Jihyun Yang, Katie L. McMahon, David A. Copland, Leander Mitchell, John D. O'Sullivan, Gerard J. Byrne, Nadeeka N. Dissanayaka
Publikováno v:
Brain and Behavior, Vol 14, Iss 3, Pp n/a-n/a (2024)
Abstract Aim Frontal and posterior‐cortical cognitive subtypes in Parkinson's disease (PD) present with executive/attention and memory/visuospatial deficits, respectively. As the posterior‐cortical subtype is predicted to progress rapidly toward
Externí odkaz:
https://doaj.org/article/215dd28463444da5bb389fa7dc69ed60
Autor:
Rosaria J. Rae, Lori L. McMahon
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 96-96 (2024)
OBJECTIVES/GOALS: Women are twice as susceptible to ailments like anxiety, PTSD, and Alzheimer’s disease compared to men. The locus coeruleus (LC), the primary source of noradrenaline for the brain is implicated in these disorders, however physiolo
Externí odkaz:
https://doaj.org/article/3b24c7eaf7a94a5ca06e223a21e60e6b
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Autor:
Lachlan T. Strike, Narelle K. Hansell, Kai-Hsiang Chuang, Jessica L. Miller, Greig I. de Zubicaray, Paul M. Thompson, Katie L. McMahon, Margaret J. Wright
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-18 (2023)
Abstract We describe the Queensland Twin Adolescent Brain (QTAB) dataset and provide a detailed methodology and technical validation to facilitate data usage. The QTAB dataset comprises multimodal neuroimaging, as well as cognitive and mental health
Externí odkaz:
https://doaj.org/article/d806e85a702e457885fffcd61be643a4
Autor:
Dana Pourzinal, Jihyun Yang, Kumareshan Sivakumaran, Katie L. McMahon, Leander Mitchell, John D. O'Sullivan, Gerard J. Byrne, Nadeeka N. Dissanayaka
Publikováno v:
Brain and Behavior, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Aim The dual syndrome hypothesis proposes that there are two cognitive subtypes in Parkinson's disease (PD): a frontal subtype with executive/attention impairment and gradual cognitive decline, and a posterior‐cortical subtype with memory/
Externí odkaz:
https://doaj.org/article/04d1ca89dca54f8cb2fe2da1c52ab29e