Zobrazeno 1 - 10
of 1 151
pro vyhledávání: '"L McGee"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract As an adoptive cellular therapy, Chimeric Antigen Receptor T cell (CAR T cell) therapy has shown remarkable success in hematological malignancies but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors prese
Externí odkaz:
https://doaj.org/article/47d1c925ddb04fb0acd9007d081551c9
Autor:
Jason E. Glenn, Kristina M. Bridges, Kakra Boye-Doe, LesLee Taylor, Jill N. Peltzer, Shawn Leigh Alexander, Danielle Binion, Matthew Schuette, Carrie L. Francis, Jerrihlyn L. McGee
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background A challenge facing many Academic Health Centers (AHCs) attempting to revise health professions education to include the impact of racism as a social and structural determinant of health (SSDoH) is a lack of broad faculty expertise
Externí odkaz:
https://doaj.org/article/90965377e9054a64b5b06b85f1607611
Autor:
Liam G. Hall, Juliane K. Czeczor, Timothy Connor, Javier Botella, Kirstie A. De Jong, Mark C. Renton, Amanda J. Genders, Kylie Venardos, Sheree D. Martin, Simon T. Bond, Kathryn Aston-Mourney, Kirsten F. Howlett, James A. Campbell, Greg R. Collier, Ken R. Walder, Matthew McKenzie, Mark Ziemann, Sean L. McGee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer’s disease. The role of amyloid beta 42 (Aβ42) in these diverse chronic diseases is obscure. Here we show that adipose tissue
Externí odkaz:
https://doaj.org/article/ade282758ba44938be3e4d25c0c6bdc1
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Autor:
Sheree D. Martin, Timothy Connor, Andrew Sanigorski, Kevin A. McEwen, Darren C. Henstridge, Brunda Nijagal, David De Souza, Dedreia L. Tull, Peter J. Meikle, Greg M. Kowalski, Clinton R. Bruce, Paul Gregorevic, Mark A. Febbraio, Fiona M. Collier, Ken R. Walder, Sean L. McGee
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Lipotoxicity, the accumulation of lipids in non-adipose tissues, alters the metabolic transcriptome and mitochondrial metabolism in skeletal muscle. The mechanisms involved remain poorly understood. Here we show that lipotoxicity increased h
Externí odkaz:
https://doaj.org/article/cb089318d6ca4cdc83eb1a778a2e7a37
Autor:
M. Nicholl, S. Srivastav, M. D. Fulton, S. Gomez, M. E. Huber, S. R. Oates, P. Ramsden, L. Rhodes, S. J. Smartt, K. W. Smith, A. Aamer, J. P. Anderson, F. E. Bauer, E. Berger, T. de Boer, K. C. Chambers, P. Charalampopoulos, T.-W. Chen, R. P. Fender, M. Fraser, H. Gao, D. A. Green, L. Galbany, B. P. Gompertz, M. Gromadzki, C. P. Gutiérrez, D. A. Howell, C. Inserra, P. G. Jonker, M. Kopsacheili, T. B. Lowe, E. A. Magnier, C. McCully, S. L. McGee, T. Moore, T. E. Müller-Bravo, M. Newsome, E. Padilla Gonzalez, C. Pellegrino, T. Pessi, M. Pursiainen, A. Rest, E. J. Ridley, B. J. Shappee, X. Sheng, G. P. Smith, G. Terreran, M. A. Tucker, J. Vinkó, R. J. Wainscoat, P. Wiseman, D. R. Young
Publikováno v:
The Astrophysical Journal Letters, Vol 954, Iss 1, p L28 (2023)
We present the discovery and extensive follow-up of a remarkable fast-evolving optical transient, AT 2022aedm, detected by the Asteroid Terrestrial impact Last Alert Survey (ATLAS). In the ATLAS o band, AT 2022aedm exhibited a rise time of 9 ± 1 day
Externí odkaz:
https://doaj.org/article/9e536d8b3d6e4799b622d317b29c44e2
Autor:
J. Blair Price, Clarissa G. Yates, Brooke A. Morath, Sam K. Van De Wakker, Nathanael J. Yates, Kim Butters, Mark A. Frye, Sean L. McGee, Susannah J. Tye
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Lithium, a mood stabilizer and common adjunctive treatment for refractory depression, shares overlapping mechanisms of action with ketamine and enhances the duration of ketamine’s antidepressant actions in rodent models at sub-therapeutic
Externí odkaz:
https://doaj.org/article/752ab944d2c949039ac5e787a45d034a
Autor:
Kirstie A De Jong, Filip Berisha, Negar Naderpoor, Alan Appelbe, Mark A Kotowicz, Kimberly Cukier, Sean L McGee, Viacheslav O Nikolaev
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263312 (2022)
BackgroundIt remains unclear as to whether polycystic ovary syndrome (PCOS) is an additional risk factor in the development of left ventricular (LV) hypertrophy in obese women. In the current study, we provide clarity on this issue by rigorously anal
Externí odkaz:
https://doaj.org/article/44230b75c9934246b8916185b4922a38
Publikováno v:
Life, Vol 13, Iss 3, p 730 (2023)
Development of OA (OA) is multifactorial and is strongly associated with risk factors such as aging, trauma, metabolic disorders, and obesity. Metabolic Syndrome (MetS)-associated OA, collectively coined MetS-OA, is an increasingly recognized entity
Externí odkaz:
https://doaj.org/article/bf76ce29bb8e4423b1eafcea0bb06213
Autor:
Marco Gullieuszik, Eric Giunchi, Bianca M. Poggianti, Alessia Moretti, Claudia Scarlata, Daniela Calzetti, Ariel Werle, Anita Zanella, Mario Radovich, Callum Bellhouse, Daniela Bettoni, Andrea Franchetto, Jacopo Fritz, Yara L. Jaffé, Sean L. McGee, Matilde Mingozzi, Alessandro Omizzolo, Stephanie Tonnesen, Marc Verheijen, Benedetta Vulcani
Publikováno v:
The Astrophysical Journal, Vol 945, Iss 1, p 54 (2023)
Star-forming, H α -emitting clumps are found embedded in the gaseous tails of galaxies undergoing intense ram pressure stripping in galaxy clusters, so-called jellyfish galaxies. These clumps offer a unique opportunity to study star formation under
Externí odkaz:
https://doaj.org/article/0a5b12b037f64f6eb163a9f117113746
Autor:
Pamela L. McGee
Publikováno v:
Journal of Professional Nursing. 47:73-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43ffdf7db9fe1eb47c9c0f4e297b5735
https://doi.org/10.1016/j.profnurs.2023.04.006
https://doi.org/10.1016/j.profnurs.2023.04.006