Zobrazeno 1 - 10
of 92
pro vyhledávání: '"L Manzino"'
Autor:
G H Johnston, Eugene John Trybulski, John C. L. Erve, Brian W. Strassle, A. Adedoyin, Jeffrey D. Kennedy, James E. Harrison, Claudine Pulicicchio, Michael J. Piesla, Peimin Lu, Kathryn E. Rogers, Puwen Zhang, Brian J. Platt, Terri Cummons, Garth T. Whiteside, Liza Leventhal, Chad E. Beyer, Zoë A. Hughes, Darlene C. Deecher, L Manzino, Lilly Mark, Jason M. Dwyer
Publikováno v:
British Journal of Pharmacology. 160:1105-1118
Background and purpose: Antidepressants, which raise the CNS concentrations of 5-HT and noradrenaline, are frequently used in the treatment of chronic pain; however, it is not known if increasing CNS noradrenaline levels alone is sufficient for effic
Publikováno v:
Acta Horticulturae. :41-48
Publikováno v:
Journal of neurochemistry. 79(1)
The neurotoxic actions of methamphetamine (METH) may be mediated in part by reactive oxygen species (ROS). Methamphetamine administration leads to increases in ROS formation and lipid peroxidation in rodent brain; however, the extent to which protein
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(3)
Disturbance in phosphorylation/dephosphorylation can trigger apoptosis. Little is known as to its effects on mesencephalic dopamine neurons, the major neurons lost in Parkinson's disease. In this study, okadaic acid (OKA), a phosphatase 1 and 2A inhi
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; September 2001, Vol. 298 Issue: 3 p925-33, 9p
Publikováno v:
Research communications in chemical pathology and pharmacology. 34(3)
Ascorbic acid was a potent inhibitor of the binding of both dopamine agonists (3H-dopamine and 3H-ADTN) and also of dopamine antagonists (3H-spiroperidol and 3H-domperidone) to neostriatal membrane preparations. Against dopamine agonists, ascorbic ac
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 217(3)
Mazindol and two homologs of mazindol were tested for their effects as uptake inhibitors in rat tissue slices for [3H]dopamine in the neostriatum, for [3H]norepinephrine in occipital cortex and for [3H]serotonin in whole brain. All three drugs were p
Publikováno v:
Substance and alcohol actions/misuse. 2(2)
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 247(1)
In rats with a unilateral lesion of the nigrostriatal dopaminergic pathway, the ipsilateral rotation produced by the enhanced actions of endogenous dopamine (DA) on the nonlesioned side, induced by either the DA-releasing drug amphetamine or the DA u
Publikováno v:
Research communications in chemical pathology and pharmacology. 47(3)
The rates of decomposition of 3H-dopamine (3H-DA), 3H-apomorphine and 3H-ADTN were determined in Tris buffer at pH 7.4 and in a Tris buffer containing a neostriatal membrane preparation representative of that used in binding experiments. In both the